2F66
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![BU of 2f66 by Molmil](/molmil-images/mine/2f66) | Structure of the ESCRT-I endosomal trafficking complex | Descriptor: | Protein SRN2, SULFATE ION, Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease, ... | Authors: | Kostelansky, M.S, Lee, S, Kim, J, Hurley, J.H. | Deposit date: | 2005-11-28 | Release date: | 2006-04-18 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural and functional organization of the ESCRT-I trafficking complex. Cell(Cambridge,Mass.), 125, 2006
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5Y0D
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![BU of 5y0d by Molmil](/molmil-images/mine/5y0d) | Crystal Structure of the human nucleosome containing the H2B E76K mutant | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | Authors: | Kurumizaka, H, Arimura, Y, Fujita, R, Noda, M. | Deposit date: | 2017-07-16 | Release date: | 2018-07-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome. Nucleic Acids Res., 46, 2018
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5ZUU
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![BU of 5zuu by Molmil](/molmil-images/mine/5zuu) | Crystal structure of AtCPSF30 YTH domain in complex with 10mer m6A-modified RNA | Descriptor: | 30-kDa cleavage and polyadenylation specificity factor 30, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | Authors: | Wu, B, Nie, H, Li, S, Patel, D.J. | Deposit date: | 2018-05-08 | Release date: | 2019-05-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | CPSF30-L-mediated recognition of mRNA m6A modification controls alternative polyadenylation of nitrate signaling-related gene transcripts in Arabidopsis. Mol Plant, 2021
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5Y0C
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![BU of 5y0c by Molmil](/molmil-images/mine/5y0c) | Crystal Structure of the human nucleosome at 2.09 angstrom resolution | Descriptor: | CHLORIDE ION, DNA (146-MER), Histone H2A type 1-B/E, ... | Authors: | Kurumizaka, H, Arimura, Y, Fujita, R, Noda, M. | Deposit date: | 2017-07-16 | Release date: | 2018-07-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.087 Å) | Cite: | Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome. Nucleic Acids Res., 46, 2018
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8TWQ
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![BU of 8twq by Molmil](/molmil-images/mine/8twq) | Structure of bacteriophage lambda RexA protein | Descriptor: | CADMIUM ION, Protein rexA, SULFATE ION | Authors: | Adams, M.C, Chappie, J.S, Schiltz, C.J. | Deposit date: | 2023-08-21 | Release date: | 2024-04-17 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The crystal structure of bacteriophage lambda RexA provides novel insights into the DNA binding properties of Rex-like phage exclusion proteins. Nucleic Acids Res., 52, 2024
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7WWF
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![BU of 7wwf by Molmil](/molmil-images/mine/7wwf) | Crystal structure of BioH3 from Mycolicibacterium smegmatis | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Esterase | Authors: | Yang, J, Xu, Y.C, Gan, J.H, Feng, Y.J. | Deposit date: | 2022-02-12 | Release date: | 2022-07-06 | Last modified: | 2023-01-18 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Three enigmatic BioH isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-TB drug target. Plos Pathog., 18, 2022
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8XK5
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![BU of 8xk5 by Molmil](/molmil-images/mine/8xk5) | SNB1G11 Fab bound to SFTSV glycoprotein Gn | Descriptor: | Envelopment polyprotein, mAb SNB1G11 Fab heavy chain, mAb SNB1G11 Fab light chain | Authors: | Deng, Z. | Deposit date: | 2023-12-22 | Release date: | 2024-07-10 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | A broadly protective antibody targeting the glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection. To Be Published
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8XK8
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![BU of 8xk8 by Molmil](/molmil-images/mine/8xk8) | N1D10 Fab bound to SFTSV glycoprotein-Gn | Descriptor: | Envelopment polyprotein, mAb N1D10 Fab heavy chain, mAb N1D10 Fab light chain | Authors: | Zhao, H, Deng, Z. | Deposit date: | 2023-12-22 | Release date: | 2024-07-10 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (3.53 Å) | Cite: | A broadly protective antibody targeting the glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection. To Be Published
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8XK6
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![BU of 8xk6 by Molmil](/molmil-images/mine/8xk6) | S2A5 Fab bound to SFTSV glycoprotein Gn | Descriptor: | Envelopment polyprotein, mAb S2A5 Fab heavy chain, mAb S2A5 Fab light chain | Authors: | Deng, Z. | Deposit date: | 2023-12-22 | Release date: | 2024-07-10 | Last modified: | 2024-07-24 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | A broadly protective antibody targeting the glycoprotein Gn inhibits severe fever with thrombocytopenia syndrome virus infection. To Be Published
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1L2I
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![BU of 1l2i by Molmil](/molmil-images/mine/1l2i) | Human Estrogen Receptor alpha Ligand-binding Domain in Complex with (R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol and a Glucocorticoid Receptor Interacting Protein 1 NR box II Peptide | Descriptor: | (R,R)-5,11-CIS-DIETHYL-5,6,11,12-TETRAHYDROCHRYSENE-2,8-DIOL, CHLORIDE ION, ESTROGEN RECEPTOR, ... | Authors: | Shiau, A.K, Barstad, D, Radek, J.T, Meyers, M.J, Nettles, K.W, Katzenellenbogen, B.S, Katzenellenbogen, J.A, Agard, D.A, Greene, G.L. | Deposit date: | 2002-02-21 | Release date: | 2002-05-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism. Nat.Struct.Biol., 9, 2002
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6JKV
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![BU of 6jkv by Molmil](/molmil-images/mine/6jkv) | PppA, a key regulatory component of T6SS in Pseudomonas aeruginosa | Descriptor: | MANGANESE (II) ION, PppA | Authors: | Wang, T, Liu, L, Wu, Y, Li, D. | Deposit date: | 2019-03-02 | Release date: | 2019-06-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of PppA from Pseudomonas aeruginosa, a key regulatory component of type VI secretion systems. Biochem.Biophys.Res.Commun., 516, 2019
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6M4C
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![BU of 6m4c by Molmil](/molmil-images/mine/6m4c) | C. albicans actin interacting protein Aip5 | Descriptor: | C. albicans actin interacting protein Aip5 | Authors: | Loh, Z.Y, Gao, Y.G, Xie, Y, Miao, Y. | Deposit date: | 2020-03-06 | Release date: | 2020-08-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Orchestrated actin nucleation by the Candida albicans polarisome complex enables filamentous growth. J.Biol.Chem., 295, 2020
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6LPI
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![BU of 6lpi by Molmil](/molmil-images/mine/6lpi) | Crystal Structure of AHAS holo-enzyme | Descriptor: | Acetolactate synthase isozyme 1 large subunit, Acetolactate synthase isozyme 1 small subunit, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Zhang, Y, Yang, X, Xi, Z, Shen, Y. | Deposit date: | 2020-01-10 | Release date: | 2020-11-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.849 Å) | Cite: | Molecular architecture of the acetohydroxyacid synthase holoenzyme. Biochem.J., 477, 2020
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2FV5
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![BU of 2fv5 by Molmil](/molmil-images/mine/2fv5) | Crystal structure of TACE in complex with IK682 | Descriptor: | (2R)-N-HYDROXY-2-[(3S)-3-METHYL-3-{4-[(2-METHYLQUINOLIN-4-YL)METHOXY]PHENYL}-2-OXOPYRROLIDIN-1-YL]PROPANAMIDE, ADAM 17, ZINC ION | Authors: | Orth, P, Niu, X. | Deposit date: | 2006-01-30 | Release date: | 2006-07-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | IK682, a tight binding inhibitor of TACE. Arch.Biochem.Biophys., 451, 2006
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7XTQ
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![BU of 7xtq by Molmil](/molmil-images/mine/7xtq) | Cryo-EM structure of the R399-bound GPBAR-Gs complex | Descriptor: | G-protein coupled bile acid receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Ma, L, Yang, F, Wu, X, Mao, C, Sun, J, Yu, X, Zhang, Y, Zhang, P. | Deposit date: | 2022-05-17 | Release date: | 2022-07-06 | Last modified: | 2022-08-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis and molecular mechanism of biased GPBAR signaling in regulating NSCLC cell growth via YAP activity. Proc.Natl.Acad.Sci.USA, 119, 2022
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8INB
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![BU of 8inb by Molmil](/molmil-images/mine/8inb) | Cryo-EM structure of Cas12j-SF05-crRNA-dsDNA complex | Descriptor: | Cas12j-SF05, NTS-DNA, TS-DNA, ... | Authors: | Zhang, X, Duan, Z.Q, Zhu, J.K. | Deposit date: | 2023-03-09 | Release date: | 2024-03-13 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular basis for DNA cleavage by the hypercompact Cas12j-SF05. Cell Discov, 9, 2023
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8JF4
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![BU of 8jf4 by Molmil](/molmil-images/mine/8jf4) | The crystal structure of human AURKA kinase domain in complex with AURKA-compound 9 | Descriptor: | 2-[4-[4-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]carbonylpiperazin-1-yl]-6-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-N-prop-2-ynyl-pyrimidine-4-carboxamide, Aurora kinase A | Authors: | Zhu, C.J. | Deposit date: | 2023-05-17 | Release date: | 2024-02-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.89288354 Å) | Cite: | Global Reactivity Profiling of the Catalytic Lysine in Human Kinome for Covalent Inhibitor Development. Angew.Chem.Int.Ed.Engl., 63, 2024
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8JF3
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![BU of 8jf3 by Molmil](/molmil-images/mine/8jf3) | C-Src in complex with compound 9 | Descriptor: | 2-[4-[4-[bis(oxidanylidene)-$l^5-sulfanyl]oxyphenyl]carbonylpiperazin-1-yl]-6-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-N-prop-2-ynyl-pyrimidine-4-carboxamide, Proto-oncogene tyrosine-protein kinase Src | Authors: | Zhang, Z.M, Huang, H.S. | Deposit date: | 2023-05-17 | Release date: | 2024-02-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.84647632 Å) | Cite: | Global Reactivity Profiling of the Catalytic Lysine in Human Kinome for Covalent Inhibitor Development. Angew.Chem.Int.Ed.Engl., 63, 2024
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8JG8
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![BU of 8jg8 by Molmil](/molmil-images/mine/8jg8) | |
7V52
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![BU of 7v52 by Molmil](/molmil-images/mine/7v52) | Structure of AdaV | Descriptor: | AdaV, FE (III) ION | Authors: | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | Deposit date: | 2021-08-16 | Release date: | 2022-08-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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7V57
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![BU of 7v57 by Molmil](/molmil-images/mine/7v57) | Structure of AdaV | Descriptor: | 2-OXOGLUTARIC ACID, AdaV, CHLORIDE ION, ... | Authors: | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | Deposit date: | 2021-08-16 | Release date: | 2022-08-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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7V54
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![BU of 7v54 by Molmil](/molmil-images/mine/7v54) | Structure of AdaV | Descriptor: | AdaV, FE (III) ION | Authors: | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | Deposit date: | 2021-08-16 | Release date: | 2022-08-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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7V56
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![BU of 7v56 by Molmil](/molmil-images/mine/7v56) | Structure of AdaV | Descriptor: | AdaV, FE (III) ION | Authors: | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | Deposit date: | 2021-08-16 | Release date: | 2022-08-24 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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7VM8
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![BU of 7vm8 by Molmil](/molmil-images/mine/7vm8) | Crystal structure of the MtDMI1 gating ring | Descriptor: | Ion channel DMI1 | Authors: | Huang, X, Zhang, P. | Deposit date: | 2021-10-08 | Release date: | 2022-08-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.034 Å) | Cite: | Constitutive activation of a nuclear-localized calcium channel complex in Medicago truncatula. Proc.Natl.Acad.Sci.USA, 119, 2022
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7V7X
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![BU of 7v7x by Molmil](/molmil-images/mine/7v7x) | Structure of H194A AdaV | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, AdaV | Authors: | Zhang, Z.Y, Chen, W.Q, Zhai, G.Q, Zhang, M. | Deposit date: | 2021-08-22 | Release date: | 2022-08-31 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural Insight into the Catalytic Mechanism of Non-Heme Iron Halogenase AdaV in 2'-Chloropentostatin Biosynthesis Acs Catalysis, 12, 2022
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