7V49
 
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2AIX
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7V48
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7D7L
 | | The crystal structure of SARS-CoV-2 papain-like protease in complex with YM155 | | Descriptor: | 1-(2-methoxyethyl)-2-methyl-3-(pyrazin-2-ylmethyl)benzo[f]benzimidazol-3-ium-4,9-dione, CAFFEINE, GLYCEROL, ... | | Authors: | Zhao, Y, Sun, L, Yang, H.T, Rao, Z.H. | | Deposit date: | 2020-10-04 | | Release date: | 2021-04-21 | | Last modified: | 2021-11-17 | | Method: | X-RAY DIFFRACTION (2.11 Å) | | Cite: | High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors.
Protein Cell, 12, 2021
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7D7K
 | | The crystal structure of SARS-CoV-2 papain-like protease in apo form | | Descriptor: | 1,2-ETHANEDIOL, CAFFEINE, Non-structural protein 3, ... | | Authors: | Zhao, Y, Sun, L, Yang, H.T, Rao, Z.H. | | Deposit date: | 2020-10-04 | | Release date: | 2021-04-21 | | Last modified: | 2021-11-17 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors.
Protein Cell, 12, 2021
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7VUN
 | | Design, modification, evaluation and cocrystal studies of novel phthalimides regulating PD-1/PD-L1 interaction | | Descriptor: | (2~{S},3~{S})-2-[[6-[(3-cyanophenyl)methoxy]-2-(2-methyl-3-phenyl-phenyl)-1,3-bis(oxidanylidene)isoindol-5-yl]methylamino]-3-oxidanyl-butanoic acid, Programmed cell death 1 ligand 1 | | Authors: | Cheng, Y, Sun, C.L, Chen, M.R, Yang, P, Xiao, Y.B. | | Deposit date: | 2021-11-03 | | Release date: | 2022-09-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.701 Å) | | Cite: | Novel phthalimides regulating PD-1/PD-L1 interaction as potential immunotherapy agents.
Acta Pharm Sin B, 12, 2022
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7WL8
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5H19
 | | EED in complex with PRC2 allosteric inhibitor EED162 | | Descriptor: | 5-(furan-2-ylmethylamino)-9-(phenylmethyl)-8,10-dihydro-7H-[1,2,4]triazolo[3,4-a][2,7]naphthyridine-6-carbonitrile, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED | | Authors: | Zhao, K, Zhao, M, Luo, X, Zhang, H. | | Deposit date: | 2016-10-08 | | Release date: | 2017-01-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED
PLoS ONE, 12, 2017
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7WL9
 | | Mouse Pendrin in chloride and bicarbonate in asymmetric state | | Descriptor: | CHLORIDE ION, Pendrin | | Authors: | Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G. | | Deposit date: | 2022-01-12 | | Release date: | 2023-04-12 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (3.78 Å) | | Cite: | Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
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7WK1
 | | Mouse Pendrin bound chloride in inward state | | Descriptor: | CHLORIDE ION, Pendrin | | Authors: | Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G. | | Deposit date: | 2022-01-08 | | Release date: | 2023-04-12 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
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7WL7
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7WLA
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7WLE
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7WL2
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7WK7
 | | Mouse Pendrin bound bicarbonate in inward state | | Descriptor: | BICARBONATE ION, Pendrin | | Authors: | Liu, Q.Y, Zhang, X, Sun, L, Chen, Z.G. | | Deposit date: | 2022-01-08 | | Release date: | 2023-05-17 | | Last modified: | 2023-08-16 | | Method: | ELECTRON MICROSCOPY (3.49 Å) | | Cite: | Asymmetric pendrin homodimer reveals its molecular mechanism as anion exchanger.
Nat Commun, 14, 2023
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7WLB
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7XO2
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7XO1
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7XO3
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7XO0
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3W2D
 | | Crystal Structure of Staphylococcal Eenterotoxin B in complex with a novel neutralization monoclonal antibody Fab fragment | | Descriptor: | Enterotoxin type B, Monoclonal Antibody 3E2 Fab figment heavy chain, Monoclonal Antibody 3E2 Fab figment light chain, ... | | Authors: | Liang, S.Y, Hu, S, Dai, J.X, Guo, Y.J, Lou, Z.Y. | | Deposit date: | 2012-11-28 | | Release date: | 2013-12-25 | | Last modified: | 2014-04-16 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis for the neutralization and specificity of Staphylococcal enterotoxin B against its MHC Class II binding site.
MAbs, 6, 2014
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7XDQ
 | | Crystal structure of a glucosylglycerol phosphorylase mutant from Marinobacter adhaerens | | Descriptor: | Glucosylglycerol phosphorylase, LITHIUM ION, beta-D-glucopyranose | | Authors: | Wei, H.L, Li, Q, Yang, J.G, Liu, W.D, Sun, Y.X. | | Deposit date: | 2022-03-28 | | Release date: | 2023-02-08 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.83 Å) | | Cite: | Protein Engineering of Glucosylglycerol Phosphorylase Facilitating Efficient and Highly Regio- and Stereoselective Glycosylation of Polyols in a Synthetic System.
Acs Catalysis, 2022
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7XDR
 | | Crystal structure of a glucosylglycerol phosphorylase from Marinobacter adhaerens | | Descriptor: | Glucosylglycerol phosphorylase | | Authors: | Wei, H.L, Li, Q, Yang, J.G, Liu, W.D, Sun, Y.X. | | Deposit date: | 2022-03-28 | | Release date: | 2023-02-08 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Protein Engineering of Glucosylglycerol Phosphorylase Facilitating Efficient and Highly Regio- and Stereoselective Glycosylation of Polyols in a Synthetic System.
Acs Catalysis, 2022
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1IYJ
 | | STRUCTURE OF A BRCA2-DSS1 COMPLEX | | Descriptor: | Deleted in split hand/split foot protein 1, breast cancer susceptibility | | Authors: | Pavletich, N.P, Jeffrey, P.D, Yang, H.J. | | Deposit date: | 2002-08-28 | | Release date: | 2002-10-02 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure.
Science, 297, 2002
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5U18
 | | Crystal structure of a methyltransferase involved in the biosynthesis of gentamicin in complex with the Geneticin | | Descriptor: | GENETICIN, N-3'' methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | | Authors: | Bury, P, Huang, F, Leadlay, P, Dias, M.V.B. | | Deposit date: | 2016-11-28 | | Release date: | 2017-11-01 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.195 Å) | | Cite: | Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis.
ACS Chem. Biol., 12, 2017
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