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2AIX

X-ray structure of the GLUR2 ligand-binding core (S1S2J) in complex with (s)-thio-atpa at 2.2 a resolution.

Summary for 2AIX
Entry DOI10.2210/pdb2aix/pdb
DescriptorGlutamate receptor 2, (S)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOTHIAZOL-4-YL) PROPRIONIC ACID (3 entities in total)
Functional Keywordsionotropic glutamate receptor glur2, ligand-binding core, agonist complex., membrane protein
Biological sourceRattus norvegicus (Norway rat)
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Cellular locationCell membrane; Multi-pass membrane protein: P19491
Total number of polymer chains1
Total formula weight29465.99
Authors
Kastrup, J.S. (deposition date: 2005-08-01, release date: 2005-08-09, Last modification date: 2024-10-09)
Primary citationHolm, M.M.,Lunn, M.L.,Traynelis, S.F.,Kastrup, J.S.,Egebjerg, J.
Distinct kinetics of ionotropic glutamate receptor 2 splice variants characterized by fast agonist application and crystallization of a receptor-ligand complex.
To be Published,
Experimental method
X-RAY DIFFRACTION (2.17 Å)
Structure validation

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