2AIX
X-ray structure of the GLUR2 ligand-binding core (S1S2J) in complex with (s)-thio-atpa at 2.2 a resolution.
Summary for 2AIX
Entry DOI | 10.2210/pdb2aix/pdb |
Descriptor | Glutamate receptor 2, (S)-2-AMINO-3-(3-HYDROXY-5-TERT-BUTYLISOTHIAZOL-4-YL) PROPRIONIC ACID (3 entities in total) |
Functional Keywords | ionotropic glutamate receptor glur2, ligand-binding core, agonist complex., membrane protein |
Biological source | Rattus norvegicus (Norway rat) More |
Cellular location | Cell membrane; Multi-pass membrane protein: P19491 |
Total number of polymer chains | 1 |
Total formula weight | 29465.99 |
Authors | Kastrup, J.S. (deposition date: 2005-08-01, release date: 2005-08-09, Last modification date: 2024-10-09) |
Primary citation | Holm, M.M.,Lunn, M.L.,Traynelis, S.F.,Kastrup, J.S.,Egebjerg, J. Distinct kinetics of ionotropic glutamate receptor 2 splice variants characterized by fast agonist application and crystallization of a receptor-ligand complex. To be Published, |
Experimental method | X-RAY DIFFRACTION (2.17 Å) |
Structure validation
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