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1EER
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BU of 1eer by Molmil
CRYSTAL STRUCTURE OF HUMAN ERYTHROPOIETIN COMPLEXED TO ITS RECEPTOR AT 1.9 ANGSTROMS
Descriptor: ERYTHROPOIETIN, ERYTHROPOIETIN RECEPTOR
Authors:Syed, R.S, Li, C.
Deposit date:1998-07-24
Release date:1999-10-01
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Efficiency of signalling through cytokine receptors depends critically on receptor orientation.
Nature, 395, 1998
2G19
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BU of 2g19 by Molmil
Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2)
Descriptor: Egl nine homolog 1, FE (II) ION, N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE
Authors:Syed, R.S, Li, V.
Deposit date:2006-02-14
Release date:2006-06-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2).
Proc.Natl.Acad.Sci.Usa, 103, 2006
1BUY
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BU of 1buy by Molmil
HUMAN ERYTHROPOIETIN, NMR MINIMIZED AVERAGE STRUCTURE
Descriptor: PROTEIN (ERYTHROPOIETIN)
Authors:Cheetham, J.C, Smith, D.M, Aoki, K.H, Stevenson, J.L, Hoeffel, T.J, Syed, R.S, Egrie, J, Harvey, T.S.
Deposit date:1998-09-08
Release date:1999-09-10
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:NMR structure of human erythropoietin and a comparison with its receptor bound conformation.
Nat.Struct.Biol., 5, 1998
1CN4
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BU of 1cn4 by Molmil
ERYTHROPOIETIN COMPLEXED WITH EXTRACELLULAR DOMAINS OF ERYTHROPOIETIN RECEPTOR
Descriptor: PROTEIN (ERYTHROPOIETIN RECEPTOR), PROTEIN (ERYTHROPOIETIN)
Authors:Stroud, R.M, Reid, S.W.
Deposit date:1999-05-25
Release date:1999-08-11
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Efficiency of signalling through cytokine receptors depends critically on receptor orientation.
Nature, 395, 1998
1SCF
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BU of 1scf by Molmil
HUMAN RECOMBINANT STEM CELL FACTOR
Descriptor: CALCIUM ION, PENTAETHYLENE GLYCOL, STEM CELL FACTOR
Authors:Jiang, X, Gurel, O, Langley, K.E, Hendrickson, W.A.
Deposit date:1998-06-04
Release date:2000-07-07
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the active core of human stem cell factor and analysis of binding to its receptor kit.
EMBO J., 19, 2000
2G1M
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BU of 2g1m by Molmil
Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2)
Descriptor: Egl nine homolog 1, FE (II) ION, N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE
Authors:Mcdonough, M.A, Schofield, C.J.
Deposit date:2006-02-14
Release date:2006-06-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2).
Proc.Natl.Acad.Sci.Usa, 103, 2006
2Y34
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BU of 2y34 by Molmil
S-nitrosylated PHD2 (NO exposed) in complex with Fe(II) and UN9
Descriptor: EGL NINE HOMOLOG 1, FE (II) ION, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE
Authors:Chowdhury, R, McDonough, M.A, Schofield, C.J.
Deposit date:2010-12-18
Release date:2010-12-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Studies on the reaction of nitric oxide with the hypoxia-inducible factor prolyl hydroxylase domain 2 (EGLN1).
J. Mol. Biol., 410, 2011
2Y33
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BU of 2y33 by Molmil
S-nitrosylated PHD2 (GSNO soaked) in complex with Zn(II) and UN9
Descriptor: EGL NINE HOMOLOG 1, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE, ZINC ION
Authors:Chowdhury, R, Clifton, I.J, Schofield, C.J.
Deposit date:2010-12-18
Release date:2010-12-29
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Studies on the Reaction of Nitric Oxide with the Hypoxia-Inducible Factor Prolyl Hydroxylase Domain 2 (Egln1)
J.Mol.Biol., 410, 2011
3HQR
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BU of 3hqr by Molmil
PHD2:Mn:NOG:HIF1-alpha substrate complex
Descriptor: Egl nine homolog 1, Hypoxia-inducible factor 1 alpha, MANGANESE (II) ION, ...
Authors:Chowdhury, R, McDonough, M.A, Schofield, C.J.
Deposit date:2009-06-08
Release date:2009-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases
Structure, 17, 2009
3HQU
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BU of 3hqu by Molmil
PHD2:Fe:UN9:partial HIF1-alpha substrate complex
Descriptor: Egl nine homolog 1, FE (II) ION, Hypoxia-inducible factor 1 alpha, ...
Authors:Chowdhury, R, McDonough, M.A, Schofield, C.J.
Deposit date:2009-06-08
Release date:2009-07-28
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases
Structure, 17, 2009

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