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7R63
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BU of 7r63 by Molmil
Nb82, a nanobody against voltage gated sodium channels Nav1.4 and Nav1.5
Descriptor: 2-(2-METHOXYETHOXY)ETHANOL, CHLORIDE ION, Nanobody Nb82, ...
Authors:Srinivasan, L, Gabelli, S.B.
Deposit date:2021-06-22
Release date:2022-05-04
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Development of high-affinity nanobodies specific for Na V 1.4 and Na V 1.5 voltage-gated sodium channel isoforms.
J.Biol.Chem., 298, 2022
8STL
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BU of 8stl by Molmil
Crystal Structure of Nanobody PIK3_Nb16 against wild-type PI3Kalpha
Descriptor: Nanobody PIK3_Nb16, SULFATE ION
Authors:Nwafor, J.N, Srinivasan, L, Chen, Z, Gabelli, S.B, Iheanacho, A, Alzogaray, V, Klinke, S.
Deposit date:2023-05-10
Release date:2024-05-22
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Development of isoform specific nanobodies for Class I PI3Ks
To be published
6MC9
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BU of 6mc9 by Molmil
Crystal Structure of Human Nav1.4 C-Terminal (1599-1754) domain in complex with calcium-bound calmodulin
Descriptor: CALCIUM ION, Calmodulin-1, Sodium channel protein type 4 subunit alpha
Authors:Yoder, J.B, Gabelli, S.B, Amzel, L.M.
Deposit date:2018-08-30
Release date:2019-04-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif.
Nat Commun, 10, 2019
6MBA
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BU of 6mba by Molmil
Crystal Structure of Human Nav1.4 CTerminal Domain in Complex with apo Calmodulin
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CARBONATE ION, ...
Authors:Yoder, J, Gabelli, S.B, Amzel, L.M.
Deposit date:2018-08-29
Release date:2019-04-10
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif.
Nat Commun, 10, 2019
5W59
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BU of 5w59 by Molmil
Crystal structure of a monomeric human FGF9 in complex with the ectodomain of human FGFR1c
Descriptor: Fibroblast growth factor 9, Fibroblast growth factor receptor 1, SULFATE ION
Authors:Mohammadi, M, Ma, J, Liu, Y.
Deposit date:2017-06-14
Release date:2017-08-16
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.498 Å)
Cite:Regulation of Receptor Binding Specificity of FGF9 by an Autoinhibitory Homodimerization.
Structure, 25, 2017

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