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7LB8
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BU of 7lb8 by Molmil
Structure of a ferrichrome importer FhuCDB from E. coli
Descriptor: Iron(3+)-hydroxamate import ATP-binding protein FhuC, Iron(3+)-hydroxamate import system permease protein FhuB, Iron(3+)-hydroxamate-binding protein FhuD
Authors:Hu, W, Zheng, H.
Deposit date:2021-01-07
Release date:2021-11-24
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM reveals unique structural features of the FhuCDB Escherichia coli ferrichrome importer.
Commun Biol, 4, 2021
4LRV
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BU of 4lrv by Molmil
Crystal structure of DndE from Escherichia coli B7A involved in DNA phosphorothioation modification
Descriptor: DNA sulfur modification protein DndE
Authors:Hu, W, Wang, C.K, Liang, J.D, Zhang, T.L, Yang, M, Hu, Z.P, Wang, Z.J, Lan, W.X, Wu, H.M, Ding, J.P, Wu, G, Deng, Z.X, Cao, C.
Deposit date:2013-07-21
Release date:2013-08-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural insights into DndE from Escherichia coli B7A involved in DNA phosphorothioation modification
Cell Res., 22, 2012
6URT
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BU of 6urt by Molmil
Extended Sensor Paddles with Bound Lipids Revealed in Mechanosensitive Channel YnaI
Descriptor: Low conductance mechanosensitive channel YnaI, O-{(R)-hydroxy[(2R)-3-(icosyloxy)-2-(tetradecanoyloxy)propoxy]phosphoryl}-L-serine
Authors:Hu, W, Wang, Z, Zheng, H.
Deposit date:2019-10-24
Release date:2020-10-28
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Extended Sensor Paddles with Bound Lipids Revealed in Mechanosensitive Channel YnaI
To Be Published
8DWI
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BU of 8dwi by Molmil
Molecular Mechanism of Sialic Acid Transport Mediated by Sialin
Descriptor: Sialin
Authors:Hu, W, Zheng, H.
Deposit date:2022-08-01
Release date:2023-01-25
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:The molecular mechanism of sialic acid transport mediated by Sialin.
Sci Adv, 9, 2023
8TNW
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BU of 8tnw by Molmil
Substrate Binding Plasticity Revealed by Cryo-EM Structures of SLC26A2
Descriptor: CHLORIDE ION, Sulfate transporter
Authors:Hu, W, Song, A.
Deposit date:2023-08-02
Release date:2024-05-22
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Substrate binding plasticity revealed by Cryo-EM structures of SLC26A2.
Nat Commun, 15, 2024
8TNX
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BU of 8tnx by Molmil
Substrate Binding Plasticity Revealed by Cryo-EM Structures of SLC26A2
Descriptor: OXALATE ION, Sulfate transporter
Authors:Hu, W, Song, A.
Deposit date:2023-08-02
Release date:2024-05-22
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:Substrate binding plasticity revealed by Cryo-EM structures of SLC26A2.
Nat Commun, 15, 2024
8TNY
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BU of 8tny by Molmil
Substrate Binding Plasticity Revealed by Cryo-EM Structures of SLC26A2
Descriptor: SULFATE ION, Sulfate transporter
Authors:Hu, W, Song, A.
Deposit date:2023-08-02
Release date:2024-05-22
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Substrate binding plasticity revealed by Cryo-EM structures of SLC26A2.
Nat Commun, 15, 2024
8VSI
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BU of 8vsi by Molmil
Mechanistic Insights Revealed by YbtPQ in the Occluded State
Descriptor: ABC transporter ATP-binding protein, ADP ORTHOVANADATE, MAGNESIUM ION, ...
Authors:Hu, W, Parkinson, C, Zheng, H.
Deposit date:2024-01-24
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanistic Insights Revealed by YbtPQ in the Occluded State.
Biomolecules, 14, 2024
7CT1
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BU of 7ct1 by Molmil
Crystal structure of Snx27 FERM domain in complex with a DLF motif
Descriptor: Fusion protein Sorting nexin-27 and DLF motif, GLYCEROL
Authors:Hu, W, Da, J, Sun, Q.
Deposit date:2020-08-17
Release date:2021-08-25
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.947 Å)
Cite:Crystal structure of Snx27 FERM domain in complex with a DLF motif
To Be Published
8H0L
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BU of 8h0l by Molmil
Sulfur binding domain of Hga complexed with phosphorothioated DNA
Descriptor: DNA (5'-D(*CP*GP*AP*GP*(PST)P*TP*CP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*GP*AP*AP*CP*TP*CP*G)-3'), MAGNESIUM ION, ...
Authors:Liu, G, He, X, Hu, W, Yang, B, Xiao, Q.
Deposit date:2022-09-29
Release date:2023-09-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Characterization of a promiscuous DNA sulfur binding domain and application in site-directed RNA base editing.
Nucleic Acids Res., 51, 2023
484D
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BU of 484d by Molmil
SOLUTION STRUCTURE OF HIV-1 REV PEPTIDE-RNA APTAMER COMPLEX
Descriptor: BASIC REV PEPTIDE, RNA APTAMER
Authors:Ye, X, Gorin, A.A, Frederick, R, Hu, W, Majumdar, A, Xu, W, Mclendon, G, Ellington, A, Patel, D.J.
Deposit date:1999-08-02
Release date:1999-10-14
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:RNA architecture dictates the conformations of a bound peptide.
Chem.Biol., 6, 1999
1NEM
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BU of 1nem by Molmil
Saccharide-RNA recognition in the neomycin B / RNA aptamer complex
Descriptor: 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranose, 2,6-diamino-2,6-dideoxy-beta-L-idopyranose-(1-3)-beta-D-ribofuranose, 2-DEOXY-D-STREPTAMINE, ...
Authors:Jiang, L, Majumdar, A, Hu, W, Jaishree, T.J, Xu, W, Patel, D.J.
Deposit date:1999-03-15
Release date:1999-08-31
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Saccharide-RNA recognition in a complex formed between neomycin B and an RNA aptamer
Structure Fold.Des., 7, 1999
1EXY
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BU of 1exy by Molmil
SOLUTION STRUCTURE OF HTLV-1 PEPTIDE BOUND TO ITS RNA APTAMER TARGET
Descriptor: HTLV-1 REX PEPTIDE, RNA APTAMER, 33-MER
Authors:Jiang, F, Gorin, A, Hu, W, Majumdar, A, Baskerville, S, Xu, W, Ellington, A, Patel, D.J.
Deposit date:2000-05-05
Release date:2000-05-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Anchoring an extended HTLV-1 Rex peptide within an RNA major groove containing junctional base triples.
Structure Fold.Des., 7, 1999
1G70
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BU of 1g70 by Molmil
COMPLEX OF HIV-1 RRE-IIB RNA WITH RSG-1.2 PEPTIDE
Descriptor: HIV-1 RRE-IIB 32 NUCLEOTIDE RNA, RSG-1.2 PEPTIDE
Authors:Gosser, Y, Hermann, T, Majumdar, A, Hu, W, Frederick, R, Jiang, F, Xu, W, Patel, D.J.
Deposit date:2000-11-08
Release date:2001-02-07
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Peptide-triggered conformational switch in HIV-1 RRE RNA complexes.
Nat.Struct.Biol., 8, 2001
8YUU
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BU of 8yuu by Molmil
Cryo-EM structure of the histamine-bound H3R-Gi complex
Descriptor: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y.
Deposit date:2024-03-27
Release date:2024-06-05
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024
8YUV
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BU of 8yuv by Molmil
Cryo-EM structure of the immepip-bound H3R-Gi complex
Descriptor: 4-(1H-imidazol-5-ylmethyl)piperidine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y.
Deposit date:2024-03-27
Release date:2024-06-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024
8YUT
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BU of 8yut by Molmil
Cryo-EM structure of the amthamine-bound H2R-Gs complex
Descriptor: 5-(2-azanylethyl)-4-methyl-1,3-thiazol-2-amine, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Shen, Q, Tang, X, Wen, X, Cheng, S, Xiao, P, Zang, S, Shen, D, Jiang, L, Zheng, Y, Zhang, H, Xu, H, Mao, C, Zhang, M, Hu, W, Sun, J, Chen, Z, Zhang, Y.
Deposit date:2024-03-27
Release date:2024-06-05
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Molecular Determinant Underlying Selective Coupling of Primary G-Protein by Class A GPCRs.
Adv Sci, 11, 2024
8JR9
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BU of 8jr9 by Molmil
Small molecule agonist (PCO371) bound to human parathyroid hormone receptor type 1 (PTH1R)
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha-1, ...
Authors:Zhao, L, He, Q, Yuan, Q, Gu, Y, He, X, Shan, H, Li, J, Wang, K, Li, Y, Hu, W, Wu, K, Shen, J, Xu, H.E.
Deposit date:2023-06-16
Release date:2023-08-02
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (2.57 Å)
Cite:Conserved class B GPCR activation by a biased intracellular agonist.
Nature, 621, 2023
6P6J
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BU of 6p6j by Molmil
Structure of YbtPQ importer with substrate Ybt-Fe bound
Descriptor: ABC transporter protein, FE (III) ION, inner membrane ABC-transporter, ...
Authors:Wang, Z, Hu, W, Zheng, H.
Deposit date:2019-06-04
Release date:2020-03-04
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Pathogenic siderophore ABC importer YbtPQ adopts a surprising fold of exporter.
Sci Adv, 6, 2020
6P6I
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BU of 6p6i by Molmil
Structure of YbtPQ importer
Descriptor: ABC transporter protein, inner membrane ABC-transporter
Authors:Wang, Z, Hu, W, Zheng, H.
Deposit date:2019-06-04
Release date:2020-03-04
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Pathogenic siderophore ABC importer YbtPQ adopts a surprising fold of exporter.
Sci Adv, 6, 2020
2BPR
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BU of 2bpr by Molmil
NMR STRUCTURE OF THE SUBSTRATE BINDING DOMAIN OF DNAK, 25 STRUCTURES
Descriptor: DNAK
Authors:Wang, H, Kurochkin, A.V, Pang, Y, Hu, W, Flynn, G.C, Zuiderweg, E.R.P.
Deposit date:1998-08-11
Release date:1999-03-02
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:NMR solution structure of the 21 kDa chaperone protein DnaK substrate binding domain: a preview of chaperone-protein interaction.
Biochemistry, 37, 1998
1L4S
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BU of 1l4s by Molmil
Solution structure of ribosome associated factor Y
Descriptor: Protein yfiA
Authors:Ye, K, Serganov, A, Hu, W, Patel, D.J.
Deposit date:2002-03-05
Release date:2002-12-04
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Ribosome-associated factor Y adopts a fold resembling a double-stranded RNA binding domain scaffold.
Eur.J.Biochem., 269, 2002
2ASQ
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BU of 2asq by Molmil
Solution Structure of SUMO-1 in Complex with a SUMO-binding Motif (SBM)
Descriptor: Protein inhibitor of activated STAT2, Small ubiquitin-related modifier 1
Authors:Song, J, Zhang, Z, Hu, W, Chen, Y.
Deposit date:2005-08-23
Release date:2005-10-11
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Small Ubiquitin-like Modifier (SUMO) Recognition of a SUMO Binding Motif: A reversal of the bound orientation
J.Biol.Chem., 280, 2005
1CKR
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BU of 1ckr by Molmil
HIGH RESOLUTION SOLUTION STRUCTURE OF THE HEAT SHOCK COGNATE-70 KD SUBSTRATE BINDING DOMAIN OBTAINED BY MULTIDIMENSIONAL NMR TECHNIQUES
Descriptor: HEAT SHOCK SUBSTRATE BINDING DOMAIN OF HSC-70
Authors:Morshauser, R.C, Hu, W, Wang, H, Pang, Y, Flynn, G.C, Zuiderweg, E.R.P.
Deposit date:1999-04-22
Release date:1999-04-30
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:High-resolution solution structure of the 18 kDa substrate-binding domain of the mammalian chaperone protein Hsc70.
J.Mol.Biol., 289, 1999
1RW2
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BU of 1rw2 by Molmil
Three-dimensional structure of Ku80 CTD
Descriptor: ATP-dependent DNA helicase II, 80 kDa subunit
Authors:Zhang, Z, Hu, W, Cano, L, Lee, T.D, Chen, D.J, Chen, Y.
Deposit date:2003-12-15
Release date:2003-12-30
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the C-terminal domain of Ku80 suggests important sites for protein-protein interactions.
STRUCTURE, 12, 2004

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