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2RAQ
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BU of 2raq by Molmil
Crystal structure of the MTH889 protein from Methanothermobacter thermautotrophicus. Northeast Structural Genomics Consortium target TT205
Descriptor: CALCIUM ION, Conserved protein MTH889
Authors:Forouhar, F, Su, M, Xu, X, Seetharaman, J, Mao, L, Xiao, R, Ma, L.-C, Conover, K, Baran, M.C, Acton, T.B, Montelione, G.T, Arrowsmith, C.H, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-09-17
Release date:2007-10-16
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.11 Å)
Cite:Crystal structure of the MTH889 protein from Methanothermobacter thermautotrophicus.
To be Published
1GZ3
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BU of 1gz3 by Molmil
Molecular mechanism for the regulation of human mitochondrial NAD(P)+-dependent malic enzyme by ATP and fumarate
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, FUMARIC ACID, MANGANESE (II) ION, ...
Authors:Yang, Z, Lanks, C.W, Tong, L.
Deposit date:2002-05-14
Release date:2003-05-22
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Mechanism for the Regulation of Human Mitochondrial Nad(P)+-Dependent Malic Enzyme by ATP and Fumarate
Structure, 10, 2002
1JQ6
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BU of 1jq6 by Molmil
HUMAN CYTOMEGALOVIRUS PROTEASE DIMER-INTERFACE MUTANT, S225Y
Descriptor: ASSEMBLIN
Authors:Batra, R, Khayat, R, Tong, L.
Deposit date:2001-08-03
Release date:2001-09-12
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular mechanism for dimerization to regulate the catalytic activity of human cytomegalovirus protease.
Nat.Struct.Biol., 8, 2001
3TC7
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BU of 3tc7 by Molmil
Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR62.
Descriptor: ACETIC ACID, Indole-3-glycerol phosphate synthase, PHOSPHATE ION
Authors:Vorobiev, S, Su, M, Bjelic, S, Kipnis, Y, Wang, L, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-08-08
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design.
J.Mol.Biol., 426, 2014
1I45
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BU of 1i45 by Molmil
YEAST TRIOSEPHOSPHATE ISOMERASE (MUTANT)
Descriptor: TRIOSEPHOSPHATE ISOMERASE
Authors:Rozovsky, S, Jogl, G, Tong, L, McDermott, A.E.
Deposit date:2001-02-19
Release date:2001-06-30
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Solution-state NMR investigations of triosephosphate isomerase active site loop motion: ligand release in relation to active site loop dynamics.
J.Mol.Biol., 310, 2001
2QGS
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BU of 2qgs by Molmil
Crystal structure of SE1688 protein from Staphylococcus epidermidis. Northeast Structural Genomics Consortium target SeR89
Descriptor: Protein SE1688, ZINC ION
Authors:Forouhar, F, Su, M, Benach, J, Seetharaman, J, Chen, C.X, Fang, Y, Cunningham, K, Owen, L, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-06-29
Release date:2007-07-17
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of SE1688 protein from Staphylococcus epidermidis.
To be Published
2QZU
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BU of 2qzu by Molmil
Crystal structure of the putative sulfatase yidJ from Bacteroides fragilis. Northeast Structural Genomics Consortium target BfR123
Descriptor: Putative sulfatase yidJ
Authors:Vorobiev, S.M, Abashidze, M, Seetharaman, J, Wang, D, Cunningham, K, Maglaqui, M, Owens, L, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2007-08-17
Release date:2007-09-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:X-ray crystal structure of the putative sulfatase yidJ from Bacteroides fragilis.
To be Published
3TC6
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BU of 3tc6 by Molmil
Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium Target OR63.
Descriptor: DI(HYDROXYETHYL)ETHER, Indole-3-glycerol phosphate synthase, PHOSPHATE ION
Authors:Vorobiev, S, Su, M, Bjelic, S, Kipnis, Y, Wang, L, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Baker, D, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-08-08
Release date:2011-08-24
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design.
J.Mol.Biol., 426, 2014
2AXP
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BU of 2axp by Molmil
X-Ray Crystal Structure of Protein BSU20280 from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR256.
Descriptor: hypothetical protein BSU20280
Authors:Forouhar, F, Abashidze, M, Friedman, D, Vorobiev, S.M, Kuzin, A.P, Ciao, M, Conover, K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-09-05
Release date:2005-09-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of the Hypothetical Protein BSU20280 from Bacillus subtilis, NESG target SR256
To be Published
1DO8
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BU of 1do8 by Molmil
CRYSTAL STRUCTURE OF A CLOSED FORM OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME
Descriptor: MALIC ENZYME, MANGANESE (II) ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Yang, Z, Floyd, D.L, Loeber, G, Tong, L.
Deposit date:1999-12-19
Release date:2000-03-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a closed form of human malic enzyme and implications for catalytic mechanism.
Nat.Struct.Biol., 7, 2000
1EFK
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BU of 1efk by Molmil
STRUCTURE OF HUMAN MALIC ENZYME IN COMPLEX WITH KETOMALONATE
Descriptor: ALPHA-KETOMALONIC ACID, MAGNESIUM ION, MALIC ENZYME, ...
Authors:Yang, Z, Floyd, D.L, Loeber, G, Tong, L.
Deposit date:2000-02-09
Release date:2000-03-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of a closed form of human malic enzyme and implications for catalytic mechanism.
Nat.Struct.Biol., 7, 2000
2BDQ
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BU of 2bdq by Molmil
Crystal Structure of the Putative Copper Homeostasis Protein CutC from Streptococcus agalactiae, Northeast Strucural Genomics Target SaR15.
Descriptor: copper homeostasis protein CutC
Authors:Forouhar, F, Abashidze, M, Jayaraman, S, Ho, C.K, Cooper, B, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-10-20
Release date:2005-11-01
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of the Putative Copper Homeostasis Protein CutC from Streptococcus agalactiae, Northeast Strucural Genomics Target SaR15.
To be Published
2BDV
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BU of 2bdv by Molmil
X-Ray Crystal Structure of Phage-related Protein BB2244 from Bordetella bronchiseptica. Northeast Structural Genomics Consortium Target BoR24.
Descriptor: phage-related conserved hypothetical protein, BB2244
Authors:Forouhar, F, Abashidze, M, Benach, J, Jayaraman, S, Janjua, H, Cooper, B, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-10-20
Release date:2005-11-01
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of the phage-related conserved hypothetical protein BB2244 from Bordetella bronchiseptica, Northeast Structural Genomics Target BoR24
To be Published
1CA4
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BU of 1ca4 by Molmil
STRUCTURE OF TNF RECEPTOR ASSOCIATED FACTOR 2 (TRAF2)
Descriptor: PROTEIN (TNF RECEPTOR ASSOCIATED FACTOR 2)
Authors:Park, Y.C, Burkitt, V, Villa, A.R, Tong, L, Wu, H.
Deposit date:1999-02-23
Release date:1999-04-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for self-association and receptor recognition of human TRAF2.
Nature, 398, 1999
6AIX
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BU of 6aix by Molmil
Crystal structure of DXO in complex with adenosine 3', 5' bisphosphate and two magnesium ions
Descriptor: ADENOSINE-3'-5'-DIPHOSPHATE, Decapping and exoribonuclease protein, MAGNESIUM ION
Authors:Chang, J.H, Tong, L.
Deposit date:2018-08-25
Release date:2018-10-17
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular mechanism for the inhibition of DXO by adenosine 3',5'-bisphosphate.
Biochem. Biophys. Res. Commun., 504, 2018
6AIY
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BU of 6aiy by Molmil
Crystal structure of DXO (E234A mutant) in complex with adenosine 3', 5' bisphosphate and two magnesium ions
Descriptor: ADENOSINE-3'-5'-DIPHOSPHATE, Decapping and exoribonuclease protein, MAGNESIUM ION
Authors:Chang, J.H, Tong, L.
Deposit date:2018-08-25
Release date:2018-10-17
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:Molecular mechanism for the inhibition of DXO by adenosine 3',5'-bisphosphate.
Biochem. Biophys. Res. Commun., 504, 2018
6AOZ
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BU of 6aoz by Molmil
Crystal structure of human FLASH N-terminal domain C54S/C83A (Crystal form 1)
Descriptor: 1,2-ETHANEDIOL, CASP8-associated protein 2
Authors:Aik, W.S, Tong, L.
Deposit date:2017-08-16
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3'-end processing.
PLoS ONE, 12, 2017
2BDE
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BU of 2bde by Molmil
Crystal Structure of the cytosolic IMP-GMP specific 5'-nucleotidase (lpg0095) from Legionella pneumophila, Northeast Structural Genomics Target LgR1
Descriptor: SULFATE ION, cytosolic IMP-GMP specific 5'-nucleotidase
Authors:Forouhar, F, Abashidze, M, Ho, C.K, Conover, K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-10-20
Release date:2005-12-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structure of the cytosolic IMP-GMP specific 5'-nucleotidase (lpg0095) from Legionella pneumophila, Northeast Structural Genomics Target LgR1
To be Published
1SBK
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BU of 1sbk by Molmil
X-RAY STRUCTURE OF YDII_ECOLI NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER29.
Descriptor: Hypothetical protein ydiI, SULFATE ION
Authors:Kuzin, A.P, Edstrom, W, Vorobiev, S.M, Lee, I, Forouhar, F, Ma, L, Chiang, Y, Rong, X, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2004-02-10
Release date:2004-02-24
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray Structure of YDII_ECOLI Northeast Structural Genomics Consortium Target ER29
To be Published
6AP0
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BU of 6ap0 by Molmil
Crystal structure of human FLASH N-terminal domain C54S/C83A (Crystal form 2)
Descriptor: CASP8-associated protein 2
Authors:Aik, W.S, Tong, L.
Deposit date:2017-08-16
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.581 Å)
Cite:The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3'-end processing.
PLoS ONE, 12, 2017
2DLB
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BU of 2dlb by Molmil
X-ray Crystal Structure of Protein yopT from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR412
Descriptor: yopT
Authors:Kuzin, A.P, Chen, Y, Seetharaman, J, Ho, C.-K, Cunningham, K, Janjua, H, Conover, K, Ma, L.-C, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2006-04-18
Release date:2006-04-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:X-ray structure of hypothetical protein from Bacillus subtilis O34498 at the resolution of 1.2A. NESG target SR412
To be published
2BDT
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BU of 2bdt by Molmil
Crystal Structure of the Putative Gluconate Kinase from Bacillus halodurans, Northeast Structural Genomics Target BhR61
Descriptor: BH3686, SULFATE ION
Authors:Forouhar, F, Abashidze, M, Jayaraman, S, Janjua, H, Cooper, B, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-10-20
Release date:2005-11-01
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal Structure of the Putative Gluconate Kinase from Bacillus halodurans, Northeast Structural Genomics Target BhR61
To be Published
6ANO
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BU of 6ano by Molmil
Crystal structure of human FLASH N-terminal domain
Descriptor: CASP8-associated protein 2
Authors:Aik, W.S, Tong, L.
Deposit date:2017-08-14
Release date:2017-11-15
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3'-end processing.
PLoS ONE, 12, 2017
2BDR
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BU of 2bdr by Molmil
Crystal Structure of the Putative Ureidoglycolate hydrolase PP4288 from Pseudomonas putida, Northeast Structural Genomics Target PpR49
Descriptor: SODIUM ION, Ureidoglycolate hydrolase
Authors:Forouhar, F, Abashidze, M, Jayaraman, S, Ho, C.K, Conover, K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-10-20
Release date:2005-11-15
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of the Putative Ureidoglycolate hydrolase PP4288 from Pseudomonas putida, Northeast Structural Genomics Target PpR49
To be Published
2B6E
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BU of 2b6e by Molmil
X-Ray Crystal Structure of Protein HI1161 from Haemophilus influenzae. Northeast Structural Genomics Consortium Target IR63.
Descriptor: ACETIC ACID, Hypothetical UPF0152 protein HI1161
Authors:Kuzin, A.P, Benach, J, Chen, Y, Acton, T, Xiao, R, Conover, K, Ma, L.-C, Kellie, R, Cunningham, K.E, Montelione, G, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2005-10-01
Release date:2005-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-Ray structure of the different crystal form of the hypothetical UPF0152 protein HI1161: NESG target IR63
TO BE PUBLISHED

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