6AP0

Crystal structure of human FLASH N-terminal domain C54S/C83A (Crystal form 2)

Summary for 6AP0

• Entry DOI: 10.2210/pdb6ap0/pdb
• Descriptor: CASP8-associated protein 2 (2 entities in total)
• Functional Keywords: coiled-coil, gene regulation
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm: Q9UKL3
• Total number of polymer chains: 2
• Total formula weight: 22667.54

Authors

Aik, W.S.,Tong, L. (deposition date: 2017-08-16, release date: 2017-11-15, Last modification date: 2023-10-04)

• Primary citation: Aik, W.S.,Lin, M.H.,Tan, D.,Tripathy, A.,Marzluff, W.F.,Dominski, Z.,Chou, C.Y.,Tong, L.; The N-terminal domains of FLASH and Lsm11 form a 2:1 heterotrimer for histone pre-mRNA 3'-end processing.; PLoS ONE, 12:e0186034-e0186034, 2017; PubMed: 29020104; DOI: 10.1371/journal.pone.0186034

Experimental method

X-RAY DIFFRACTION (2.581 Å)