6II4
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![BU of 6ii4 by Molmil](/molmil-images/mine/6ii4) | Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L4A-14 | Descriptor: | Heavy chain of L4A-14 Fab, Hemagglutinin, Light chain of L4A-14 Fab | Authors: | Jiang, H.H, Shi, Y, Qi, J, Gao, G.F. | Deposit date: | 2018-10-03 | Release date: | 2018-10-24 | Last modified: | 2019-02-06 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans. Nat Microbiol, 4, 2019
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7YCK
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![BU of 7yck by Molmil](/molmil-images/mine/7yck) | Crystal structure of SARS-CoV-2 Spike RBD in complex with FP-12A Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, FP-12A Fab heavy chain, FP-12A Fab light chain, ... | Authors: | Nguyen, V.H.T, Chen, X. | Deposit date: | 2022-07-01 | Release date: | 2023-02-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2. Nat Commun, 14, 2023
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7YCL
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![BU of 7ycl by Molmil](/molmil-images/mine/7ycl) | Crystal structure of SARS-CoV-2 Spike RBD in complex with IS-9A Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, IS-9A Fab heavy chain, IS-9A Fab light chain, ... | Authors: | Mohapatra, A, Chen, X. | Deposit date: | 2022-07-01 | Release date: | 2023-02-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2. Nat Commun, 14, 2023
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7YCN
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7DXI
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![BU of 7dxi by Molmil](/molmil-images/mine/7dxi) | |
7LYI
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![BU of 7lyi by Molmil](/molmil-images/mine/7lyi) | Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAWJ9-36-3 | Descriptor: | 3C-like proteinase, GLYCEROL, SODIUM ION, ... | Authors: | Sacco, M, Wang, J, Chen, Y. | Deposit date: | 2021-03-07 | Release date: | 2021-03-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Rational Design of Hybrid SARS-CoV-2 Main Protease Inhibitors Guided by the Superimposed Cocrystal Structures with the Peptidomimetic Inhibitors GC-376, Telaprevir, and Boceprevir. Acs Pharmacol Transl Sci, 4, 2021
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7LYH
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![BU of 7lyh by Molmil](/molmil-images/mine/7lyh) | Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAWJ9-36-1 | Descriptor: | 3C-like proteinase, GLYCEROL, benzyl (1S,3aR,6aS)-1-({(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}carbamoyl)hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate | Authors: | Sacco, M, Wang, J, Chen, Y. | Deposit date: | 2021-03-07 | Release date: | 2021-03-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Rational Design of Hybrid SARS-CoV-2 Main Protease Inhibitors Guided by the Superimposed Cocrystal Structures with the Peptidomimetic Inhibitors GC-376, Telaprevir, and Boceprevir. Acs Pharmacol Transl Sci, 4, 2021
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6Y3X
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7NG2
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![BU of 7ng2 by Molmil](/molmil-images/mine/7ng2) | Crystal structure of Toxoplasma CPSF4-YTH domain in apo form | Descriptor: | ISOPROPYL ALCOHOL, Zinc finger (CCCH type) motif-containing protein | Authors: | Swale, C, Bowler, M.W. | Deposit date: | 2021-02-08 | Release date: | 2021-07-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.23 Å) | Cite: | A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma . Elife, 10, 2021
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7NJC
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7NH2
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![BU of 7nh2 by Molmil](/molmil-images/mine/7nh2) | Crystal structure of Toxoplasma CPSF4-YTH domain bound to m6A | Descriptor: | TETRAETHYLENE GLYCOL, Zinc finger (CCCH type) motif-containing protein, ~{N},9-dimethylpurin-6-amine | Authors: | Swale, C, Bowler, M.W. | Deposit date: | 2021-02-09 | Release date: | 2021-07-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | A plant-like mechanism coupling m6A reading to polyadenylation safeguards transcriptome integrity and developmental gene partitioning in Toxoplasma . Elife, 10, 2021
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8FFR
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![BU of 8ffr by Molmil](/molmil-images/mine/8ffr) | Revised structure of the rabies virus nucleoprotein-RNA complex | Descriptor: | Nucleoprotein, PHOSPHATE ION, RNA (99-MER) | Authors: | Leyrat, C, Bourhis, J.M, Albertini, A.A.V, Wernimont, A.K, Muziol, T, Ravelli, R.B.G, Weissenhorn, W, Ruigrok, R.W.H, Jamin, M. | Deposit date: | 2022-12-09 | Release date: | 2023-01-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.49 Å) | Cite: | Structure and Dynamics of the Unassembled Nucleoprotein of Rabies Virus in Complex with Its Phosphoprotein Chaperone Module. Viruses, 14, 2022
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7Q4A
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![BU of 7q4a by Molmil](/molmil-images/mine/7q4a) | Toxoplasma gondii PRP4K kinase domain (L715F) bound to altiratinib | Descriptor: | Altiratinib, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Swale, C, Bellini, V, Bowler, M. | Deposit date: | 2021-10-29 | Release date: | 2022-08-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Altiratinib blocks Toxoplasma gondii and Plasmodium falciparum development by selectively targeting a spliceosome kinase. Sci Transl Med, 14, 2022
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7PON
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7PNO
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![BU of 7pno by Molmil](/molmil-images/mine/7pno) | C terminal domain of Nipah Virus Phosphoprotein fused to the Ntail alpha more of the Nucleoprotein. | Descriptor: | Phosphoprotein, alpha MoRE of Nipah virus Nucleoprotein tail | Authors: | Bourhis, J.M, Yabukaski, F, Tarbouriech, N, Jamin, M. | Deposit date: | 2021-09-07 | Release date: | 2022-04-20 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Structural Dynamics of the C-terminal X Domain of Nipah and Hendra Viruses Controls the Attachment to the C-terminal Tail of the Nucleocapsid Protein. J.Mol.Biol., 434, 2022
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8B8V
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7P9B
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![BU of 7p9b by Molmil](/molmil-images/mine/7p9b) | Providencia stuartii Arginine decarboxylase (Adc), decamer structure | Descriptor: | Biodegradative arginine decarboxylase | Authors: | Jessop, M, Desfosses, A, Bacia-Verloop, M, Gutsche, I. | Deposit date: | 2021-07-26 | Release date: | 2022-04-20 | Method: | ELECTRON MICROSCOPY (2.45 Å) | Cite: | Structural and biochemical characterisation of the Providencia stuartii arginine decarboxylase shows distinct polymerisation and regulation. Commun Biol, 5, 2022
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7PK6
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![BU of 7pk6 by Molmil](/molmil-images/mine/7pk6) | Providencia stuartii Arginine decarboxylase (Adc), stack structure | Descriptor: | Biodegradative arginine decarboxylase | Authors: | Jessop, M, Desfosses, A, Bacia-Verloop, M, Gutsche, I. | Deposit date: | 2021-08-25 | Release date: | 2022-04-20 | Method: | ELECTRON MICROSCOPY (2.15 Å) | Cite: | Structural and biochemical characterisation of the Providencia stuartii arginine decarboxylase shows distinct polymerisation and regulation. Commun Biol, 5, 2022
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2JTX
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8OLV
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![BU of 8olv by Molmil](/molmil-images/mine/8olv) | Structure of Oceanobacillus iheyensis group II intron in the presence of K+, Mg2+ and ARN25850 | Descriptor: | 2-[2,6-bis(bromanyl)-3,4,5-tris(oxidanyl)phenyl]carbonyl-~{N}-(2-pyrrolidin-1-ylethyl)-1-benzofuran-5-carboxamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Group IIC intron, ... | Authors: | Silvestri, I, Marcia, M. | Deposit date: | 2023-03-30 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nat Commun, 2024
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8RUH
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8RUI
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![BU of 8rui by Molmil](/molmil-images/mine/8rui) | Structure of Oceanobacillus iheyensis group II intron in the presence of K+, Mg2+, 5'-exon, and intronistat B after 1h soaking | Descriptor: | Domains 1-5, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Silvestri, I, Marcia, M. | Deposit date: | 2024-01-30 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nat Commun, 2024
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8RUJ
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![BU of 8ruj by Molmil](/molmil-images/mine/8ruj) | Structure of Oceanobacillus iheyensis group II intron in the presence of K+, Mg2+, 5'-exon, and ARN25850 after 1h soaking | Descriptor: | 2-[2,6-bis(bromanyl)-3,4,5-tris(oxidanyl)phenyl]carbonyl-~{N}-(2-pyrrolidin-1-ylethyl)-1-benzofuran-5-carboxamide, Domains 1-5, MAGNESIUM ION, ... | Authors: | Silvestri, I, Marcia, M. | Deposit date: | 2024-01-30 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nat Commun, 2024
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8RUL
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8RUM
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![BU of 8rum by Molmil](/molmil-images/mine/8rum) | Structure of Oceanobacillus iheyensis group II intron in the presence of Li+, Mg2+, and intronistat B | Descriptor: | Domains 1-5, MAGNESIUM ION, ~{N}-(2-pyrrolidin-1-ylethyl)-2-[3,4,5-tris(oxidanyl)phenyl]carbonyl-1-benzofuran-5-carboxamide | Authors: | Silvestri, I, Marcia, M. | Deposit date: | 2024-01-31 | Release date: | 2024-06-19 | Method: | X-RAY DIFFRACTION (3.62 Å) | Cite: | Targeting the conserved active site of splicing machines with specific and selective small molecule modulators Nat Commun, 2024
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