8GAF
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![BU of 8gaf by Molmil](/molmil-images/mine/8gaf) | Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | Descriptor: | Cas11, Cas5, Cas7, ... | Authors: | Hu, C, Nam, K.H, Ke, A. | Deposit date: | 2023-02-22 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
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8GAM
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![BU of 8gam by Molmil](/molmil-images/mine/8gam) | Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | Descriptor: | Cas11, Cas5, Cas7, ... | Authors: | Hu, C, Nam, K.H, Ke, A. | Deposit date: | 2023-02-23 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
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8GAN
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![BU of 8gan by Molmil](/molmil-images/mine/8gan) | Exploiting Activation and Inactivation Mechanisms in Type I-C CRISPR-Cas3 for Genome Editing Applications | Descriptor: | Cas11, Cas5, Cas7, ... | Authors: | Hu, C, Nam, K.H, Ke, A. | Deposit date: | 2023-02-23 | Release date: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | Exploiting activation and inactivation mechanisms in type I-C CRISPR-Cas3 for genome-editing applications. Mol.Cell, 84, 2024
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6K1G
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![BU of 6k1g by Molmil](/molmil-images/mine/6k1g) | Crystal structure of the L-fucose isomerase soaked with Mn2+ from Raoultella sp. | Descriptor: | L-fucose isomerase, MANGANESE (II) ION | Authors: | Kim, I.J, Kim, D.H, Nam, K.H, Kim, K.H. | Deposit date: | 2019-05-10 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | Enzymatic synthesis of l-fucose from l-fuculose using a fucose isomerase fromRaoultellasp. and the biochemical and structural analyses of the enzyme. Biotechnol Biofuels, 12, 2019
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6K1F
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![BU of 6k1f by Molmil](/molmil-images/mine/6k1f) | Crystal structure of the L-fucose isomerase from Raoultella sp. | Descriptor: | L-fucose isomerase, MANGANESE (II) ION | Authors: | Kim, I.J, Kim, D.H, Nam, K.H, Kim, K.H. | Deposit date: | 2019-05-10 | Release date: | 2020-05-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Enzymatic synthesis of l-fucose from l-fuculose using a fucose isomerase fromRaoultellasp. and the biochemical and structural analyses of the enzyme. Biotechnol Biofuels, 12, 2019
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7TR6
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![BU of 7tr6 by Molmil](/molmil-images/mine/7tr6) | Cascade complex from type I-A CRISPR-Cas system | Descriptor: | Cas11a, Cas5a, Cas7a, ... | Authors: | Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A. | Deposit date: | 2022-01-28 | Release date: | 2022-08-10 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools. Mol.Cell, 82, 2022
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7TR8
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![BU of 7tr8 by Molmil](/molmil-images/mine/7tr8) | Cascade complex from type I-A CRISPR-Cas system | Descriptor: | CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ... | Authors: | Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A. | Deposit date: | 2022-01-28 | Release date: | 2022-08-10 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools. Mol.Cell, 82, 2022
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7TRA
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![BU of 7tra by Molmil](/molmil-images/mine/7tra) | Cascade complex from type I-A CRISPR-Cas system | Descriptor: | CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ... | Authors: | Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A. | Deposit date: | 2022-01-28 | Release date: | 2022-08-10 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools. Mol.Cell, 82, 2022
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7TR9
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![BU of 7tr9 by Molmil](/molmil-images/mine/7tr9) | Cascade complex from type I-A CRISPR-Cas system | Descriptor: | CRISPR-associated endonuclease Cas3-HD, CRISPR-associated helicase Cas3, Cas11a, ... | Authors: | Hu, C, Ni, D, Nam, K.H, Majumdar, S, McLean, J, Stahlberg, H, Terns, M, Ke, A. | Deposit date: | 2022-01-28 | Release date: | 2022-08-10 | Last modified: | 2022-08-24 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools. Mol.Cell, 82, 2022
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3V9A
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![BU of 3v9a by Molmil](/molmil-images/mine/3v9a) | |
4QQY
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![BU of 4qqy by Molmil](/molmil-images/mine/4qqy) | Crystal structure of T. fusca Cas3-ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CRISPR-associated helicase, Cas3 family, ... | Authors: | Ke, A, Huo, Y, Nam, K.H. | Deposit date: | 2014-06-30 | Release date: | 2014-08-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation. Nat.Struct.Mol.Biol., 21, 2014
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4QQZ
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![BU of 4qqz by Molmil](/molmil-images/mine/4qqz) | Crystal structure of T. fusca Cas3-AMPPNP | Descriptor: | CRISPR-associated helicase, Cas3 family, DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ... | Authors: | Ke, A, Huo, Y, Nam, K.H. | Deposit date: | 2014-06-30 | Release date: | 2014-08-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.93 Å) | Cite: | Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation. Nat.Struct.Mol.Biol., 21, 2014
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5Y8Q
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![BU of 5y8q by Molmil](/molmil-images/mine/5y8q) | ZsYellow at pH 8.0 | Descriptor: | GFP-like fluorescent chromoprotein FP538 | Authors: | Bae, J.E, Kim, I.J, Nam, K.H. | Deposit date: | 2017-08-21 | Release date: | 2017-09-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Disruption of the hydrogen bonding network determines the pH-induced non-fluorescent state of the fluorescent protein ZsYellow by protonation of Glu221. Biochem. Biophys. Res. Commun., 493, 2017
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5Y4J
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![BU of 5y4j by Molmil](/molmil-images/mine/5y4j) | |
5Y4I
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![BU of 5y4i by Molmil](/molmil-images/mine/5y4i) | Crystal structure of glucose isomerase in complex with glycerol in one metal binding mode | Descriptor: | ACETATE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Bae, J.E, Kim, I.J, Nam, K.H. | Deposit date: | 2017-08-03 | Release date: | 2017-09-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Crystal structure of glucose isomerase in complex with xylitol inhibitor in one metal binding mode Biochem. Biophys. Res. Commun., 493, 2017
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6AA7
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![BU of 6aa7 by Molmil](/molmil-images/mine/6aa7) | |
5Z6V
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![BU of 5z6v by Molmil](/molmil-images/mine/5z6v) | |
5Y8R
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![BU of 5y8r by Molmil](/molmil-images/mine/5y8r) | ZsYellow at pH 3.5 | Descriptor: | GFP-like fluorescent chromoprotein FP538 | Authors: | Bae, J.E, Kim, I.J, Nam, K.H. | Deposit date: | 2017-08-21 | Release date: | 2017-09-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Disruption of the hydrogen bonding network determines the pH-induced non-fluorescent state of the fluorescent protein ZsYellow by protonation of Glu221. Biochem. Biophys. Res. Commun., 493, 2017
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6J43
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![BU of 6j43 by Molmil](/molmil-images/mine/6j43) | Proteinase K determined by PAL-XFEL | Descriptor: | CALCIUM ION, Proteinase K | Authors: | Lee, S.J, Park, J. | Deposit date: | 2019-01-07 | Release date: | 2020-01-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Application of a high-throughput microcrystal delivery system to serial femtosecond crystallography. J.Appl.Crystallogr., 53, 2020
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2OHE
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![BU of 2ohe by Molmil](/molmil-images/mine/2ohe) | Structural and mutational analysis of tRNA-Intron splicing endonuclease from Thermoplasma acidophilum DSM 1728 | Descriptor: | tRNA-splicing endonuclease | Authors: | Kim, Y.K, Mizutani, K, Rhee, K.H, Lee, W.H, Park, S.Y, Hwang, K.Y. | Deposit date: | 2007-01-10 | Release date: | 2007-11-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and Mutational Analysis of tRNA Intron-Splicing Endonuclease from Thermoplasma acidophilum DSM 1728: Catalytic Mechanism of tRNA Intron-Splicing Endonucleases J.Bacteriol., 189, 2007
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2OHC
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![BU of 2ohc by Molmil](/molmil-images/mine/2ohc) | structural and mutational analysis of tRNA-intron splicing endonuclease from Thermoplasma acidophilum DSM1728 | Descriptor: | tRNA-splicing endonuclease | Authors: | Kim, Y.K, Mizutani, K, Rhee, K.H, Lee, W.H, Park, S.Y, Hwang, K.Y. | Deposit date: | 2007-01-10 | Release date: | 2007-11-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and Mutational Analysis of tRNA Intron-Splicing Endonuclease from Thermoplasma acidophilum DSM 1728: Catalytic Mechanism of tRNA Intron-Splicing Endonucleases J.Bacteriol., 189, 2007
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7MID
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![BU of 7mid by Molmil](/molmil-images/mine/7mid) | Sub-complex of Cas4-Cas1-Cas2 bound PAM containing DNA | Descriptor: | CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (33-MER), ... | Authors: | Hu, C.Y, Ke, A.K. | Deposit date: | 2021-04-16 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.56 Å) | Cite: | Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas. Nature, 598, 2021
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7MI9
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![BU of 7mi9 by Molmil](/molmil-images/mine/7mi9) | Full integration complex of Cas1/Cas2 from Cas4-containing system | Descriptor: | CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (5'-D(P*CP*GP*GP*AP*AP*AP*AP*GP*AP*GP*CP*C)-3'), ... | Authors: | Hu, C.Y, Ke, A.K. | Deposit date: | 2021-04-16 | Release date: | 2021-11-17 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.89 Å) | Cite: | Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas. Nature, 598, 2021
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7MI4
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![BU of 7mi4 by Molmil](/molmil-images/mine/7mi4) | Symmetrical PAM-PAM prespacer bound Cas4/Cas1/Cas2 complex | Descriptor: | CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (35-MER), ... | Authors: | Hu, C.Y, Ke, A.K. | Deposit date: | 2021-04-16 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas. Nature, 598, 2021
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7MI5
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![BU of 7mi5 by Molmil](/molmil-images/mine/7mi5) | Asymmetrical PAM-Non PAM prespacer bound Cas4/Cas1/Cas2 complex | Descriptor: | CRISPR-associated endoribonuclease Cas2, CRISPR-associated exonuclease Cas4/endonuclease Cas1 fusion, DNA (26-MER), ... | Authors: | Hu, C.Y, Ke, A.K. | Deposit date: | 2021-04-16 | Release date: | 2021-11-17 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas. Nature, 598, 2021
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