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6K61
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BU of 6k61 by Molmil
Cryo-EM structure of the tetrameric photosystem I from a heterocyst-forming cyanobacterium Anabaena sp. PCC7120
Descriptor: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ...
Authors:Zheng, L, Li, Y, Li, X, Zhong, Q, Li, N, Zhang, K, Zhang, Y, Chu, H, Ma, C, Li, G, Zhao, J, Gao, N.
Deposit date:2019-05-31
Release date:2019-10-09
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.37 Å)
Cite:Structural and functional insights into the tetrameric photosystem I from heterocyst-forming cyanobacteria.
Nat.Plants, 5, 2019
8H67
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BU of 8h67 by Molmil
type I-B Cascade bound to a PAM-containing dsDNA target at 3.8 angstrom resolution.
Descriptor: CRISPR RNA, CRISPR associated protein Cas11b, CRISPR associated protein Cas5, ...
Authors:Xiao, Y, Lu, M, Yu, C, Zhang, Y.
Deposit date:2022-10-15
Release date:2024-05-01
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure and genome editing of type I-B CRISPR-Cas.
Nat Commun, 15, 2024
3SZ0
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BU of 3sz0 by Molmil
Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans in complex with sodium selenide
Descriptor: DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, SELENIUM ATOM, ...
Authors:Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H.
Deposit date:2011-07-18
Release date:2012-05-16
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2.1501 Å)
Cite:Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
3SY4
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BU of 3sy4 by Molmil
Crystal structure of sulfide:quinone oxidoreductase Ser126Ala variant from Acidithiobacillus ferrooxidans
Descriptor: DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, HYDROSULFURIC ACID, ...
Authors:Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H.
Deposit date:2011-07-15
Release date:2012-05-16
Last modified:2012-06-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
3SYI
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BU of 3syi by Molmil
Crystal structure of sulfide:quinone oxidoreductase Ser126Ala variant from Acidithiobacillus ferrooxidans using 7.0 keV diffraction data
Descriptor: DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, HYDROSULFURIC ACID, ...
Authors:Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H.
Deposit date:2011-07-17
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2001 Å)
Cite:Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
3SZF
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BU of 3szf by Molmil
Crystal structure of sulfide:quinone oxidoreductase H198A variant from Acidithiobacillus ferrooxidans in complex with bound trisulfide and decylubiquinone
Descriptor: 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H.
Deposit date:2011-07-18
Release date:2012-05-16
Last modified:2014-05-07
Method:X-RAY DIFFRACTION (2.0994 Å)
Cite:Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
3SZW
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BU of 3szw by Molmil
Crystal structure of sulfide:quinone oxidoreductase Cys128Ser variant from Acidithiobacillus ferrooxidans in complex with decylubiquinone
Descriptor: 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H.
Deposit date:2011-07-19
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
3TFV
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BU of 3tfv by Molmil
Crystal structure of dehydrosqualene synthase (crtm) from s. aureus complexed with bph-1154
Descriptor: 5-bromo-2-{[3-(octyloxy)benzyl]sulfanyl}benzoic acid, Dehydrosqualene synthase, MAGNESIUM ION
Authors:Lin, F.-Y, Zhang, Y, Liu, Y.-L, Oldfield, E.
Deposit date:2011-08-16
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Dual dehydrosqualene/squalene synthase inhibitors: leads for innate immune system-based therapeutics.
Chemmedchem, 7, 2012
3T14
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BU of 3t14 by Molmil
Crystal structure of sulfide:quinone oxidoreductase Cys128Ala variant from Acidithiobacillus ferrooxidans with bound disulfide
Descriptor: DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, HYDROSULFURIC ACID, ...
Authors:Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H.
Deposit date:2011-07-21
Release date:2012-05-16
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structure-activity characterization of sulfide:quinone oxidoreductase variants.
J.Struct.Biol., 178, 2012
8IP0
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BU of 8ip0 by Molmil
Cryo-EM structure of type I-B Cascade bound to a PAM-containing dsDNA target at 3.6 angstrom resolution
Descriptor: CRISPR associated protein Cas11b, DNA (41-MER), DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ...
Authors:Xiao, Y, Lu, M, Yu, C, Zhang, Y.
Deposit date:2023-03-13
Release date:2024-03-20
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure and genome editing of type I-B CRISPR-Cas.
Nat Commun, 15, 2024
5ZIT
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BU of 5zit by Molmil
Crystal structure of human Enterovirus D68 RdRp in complex with NADPH
Descriptor: DI(HYDROXYETHYL)ETHER, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, RdRp
Authors:Wang, M.L, Li, L, Chen, Y.P, Jiang, H, Zhang, Y, Su, D.
Deposit date:2018-03-17
Release date:2019-04-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.196 Å)
Cite:Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel.
J.Struct.Biol., 2020
3UV7
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BU of 3uv7 by Molmil
Ec_IspH in complex with buta-2,3-dienyl diphosphate (1300)
Descriptor: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER, buta-2,3-dien-1-yl trihydrogen diphosphate
Authors:Span, I, Wang, K, Wang, W, Zhang, Y, Bacher, A, Eisenreich, W, Schulz, C, Oldfield, E, Groll, M.
Deposit date:2011-11-29
Release date:2012-09-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery of acetylene hydratase activity of the iron-sulphur protein IspH.
Nat Commun, 3, 2012
3UV6
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BU of 3uv6 by Molmil
Ec_IspH in complex with 4-hydroxybutyl diphosphate (1301)
Descriptor: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 4-hydroxybutyl trihydrogen diphosphate, IRON/SULFUR CLUSTER
Authors:Span, I, Wang, K, Wang, W, Zhang, Y, Bacher, A, Eisenreich, W, Schulz, C, Oldfield, E, Groll, M.
Deposit date:2011-11-29
Release date:2012-09-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Discovery of acetylene hydratase activity of the iron-sulphur protein IspH.
Nat Commun, 3, 2012
3UWM
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BU of 3uwm by Molmil
Ec_IspH in complex with 4-oxobutyl diphosphate (1302)
Descriptor: (3E)-4-hydroxybut-3-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 4-oxobutyl trihydrogen diphosphate, ...
Authors:Span, I, Wang, K, Wang, W, Zhang, Y, Bacher, A, Eisenreich, W, Schulz, C, Oldfield, E, Groll, M.
Deposit date:2011-12-02
Release date:2012-09-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Discovery of acetylene hydratase activity of the iron-sulphur protein IspH.
Nat Commun, 3, 2012
3V5J
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BU of 3v5j by Molmil
Crystal Structure of Interleukin-2 Inducible T-cell Kinase Itk Catalytic Domain with Thienopyrazolylindole Inhibitor 090
Descriptor: 3-[4-(2-morpholin-4-ylethoxy)-2-(1~{H}-thieno[3,2-c]pyrazol-3-yl)-1~{H}-indol-6-yl]pentan-3-ol, SULFATE ION, Tyrosine-protein kinase ITK/TSK
Authors:McLean, L.R, Zhang, Y.
Deposit date:2011-12-16
Release date:2012-05-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase.
Bioorg.Med.Chem.Lett., 22, 2012
3V8T
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BU of 3v8t by Molmil
Crystal Structure of Interleukin-2 Inducible T-cell Kinase Itk Catalytic Domain with Thienopyrazolylindole Inhibitor 477
Descriptor: 3-{2-[5-(difluoromethyl)-2H-thieno[3,2-c]pyrazol-3-yl]-1H-indol-6-yl}pentan-3-ol, SULFATE ION, Tyrosine-protein kinase ITK/TSK
Authors:McLean, L.R, Zhang, Y.
Deposit date:2011-12-23
Release date:2012-05-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase.
Bioorg.Med.Chem.Lett., 22, 2012
3VF8
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BU of 3vf8 by Molmil
Crystal Structure of Spleen Tyrosine Kinase Syk Catalytic Domain with Pyrazolylbenzimidazole Inhibitor 416
Descriptor: 3-[5-(5-ethoxy-6-fluoro-1H-benzimidazol-2-yl)-1H-pyrazol-4-yl]-1,1-diethylurea, Tyrosine-protein kinase SYK
Authors:McLean, L.R, Zhang, Y.
Deposit date:2012-01-09
Release date:2012-05-02
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase.
Bioorg.Med.Chem.Lett., 22, 2012
7E33
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BU of 7e33 by Molmil
Serotonin 1E (5-HT1E) receptor-Gi protein complex
Descriptor: 3-(1-methylpiperidin-4-yl)-1H-indol-5-ol, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Xu, P, Huang, S, Zhang, H, Mao, C, Zhou, X.E, Shen, D.D, Jiang, Y, Zhang, Y, Xu, H.E.
Deposit date:2021-02-07
Release date:2021-04-14
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural insights into the lipid and ligand regulation of serotonin receptors.
Nature, 592, 2021
7E2Y
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BU of 7e2y by Molmil
Serotonin-bound Serotonin 1A (5-HT1A) receptor-Gi protein complex
Descriptor: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Xu, P, Huang, S, Zhang, H, Mao, C, Zhou, X.E, Shen, D.D, Jiang, Y, Zhang, Y, Xu, H.E.
Deposit date:2021-02-07
Release date:2021-04-14
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into the lipid and ligand regulation of serotonin receptors.
Nature, 592, 2021
7E2Z
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BU of 7e2z by Molmil
Aripiprazole-bound serotonin 1A (5-HT1A) receptor-Gi protein complex
Descriptor: 7-[4-[4-[2,3-bis(chloranyl)phenyl]piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Xu, P, Huang, S, Zhang, H, Mao, C, Zhou, X.E, Shen, D.D, Jiang, Y, Zhang, Y, Xu, H.E.
Deposit date:2021-02-07
Release date:2021-04-14
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into the lipid and ligand regulation of serotonin receptors.
Nature, 592, 2021
7E2X
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BU of 7e2x by Molmil
Apo serotonin 1A (5-HT1A) receptor-Gi protein complex
Descriptor: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Xu, P, Huang, S, Zhang, H, Mao, C, Zhou, X.E, Shen, D.D, Jiang, Y, Zhang, Y, Xu, H.E.
Deposit date:2021-02-07
Release date:2021-04-14
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into the lipid and ligand regulation of serotonin receptors.
Nature, 592, 2021
7E32
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BU of 7e32 by Molmil
Serotonin 1D (5-HT1D) receptor-Gi protein complex
Descriptor: CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
Authors:Xu, P, Huang, S, Zhang, H, Mao, C, Zhou, X.E, Shen, D.D, Jiang, Y, Zhang, Y, Xu, H.E.
Deposit date:2021-02-07
Release date:2021-04-21
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural insights into the lipid and ligand regulation of serotonin receptors.
Nature, 592, 2021
3UTC
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BU of 3utc by Molmil
Ec_IspH in complex with (E)-4-hydroxybut-3-enyl diphosphate
Descriptor: (3E)-4-hydroxybut-3-en-1-yl trihydrogen diphosphate, 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, IRON/SULFUR CLUSTER
Authors:Span, I, Wang, K, Wang, W, Zhang, Y, Bacher, A, Eisenreich, W, Li, K, Schulz, C, Oldfield, E, Groll, M.
Deposit date:2011-11-25
Release date:2012-09-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Discovery of acetylene hydratase activity of the iron-sulphur protein IspH.
Nat Commun, 3, 2012
3V5L
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BU of 3v5l by Molmil
Crystal Structure of Interleukin-2 Inducible T-cell Kinase Itk Catalytic Domain with Thienopyrazolylindole Inhibitor 542
Descriptor: 3-[3-(4-methoxyphenyl)-2-(1H-thieno[3,2-c]pyrazol-3-yl)-1H-indol-6-yl]pentan-3-ol, SULFATE ION, Tyrosine-protein kinase ITK/TSK
Authors:McLean, L.R, Zhang, Y.
Deposit date:2011-12-16
Release date:2012-05-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase.
Bioorg.Med.Chem.Lett., 22, 2012
6K4S
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BU of 6k4s by Molmil
Crystal structure of xCas9 in complex with sgRNA and DNA (TGC PAM)
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, non-targeted DNA, sgRNA, ...
Authors:Chen, W, Zhang, H, Zhang, Y, Wang, Y, Gan, J, Ji, Q.
Deposit date:2019-05-26
Release date:2019-09-25
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Molecular basis for the PAM expansion and fidelity enhancement of an evolved Cas9 nuclease.
Plos Biol., 17, 2019

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