8IP0

Cryo-EM structure of type I-B Cascade bound to a PAM-containing dsDNA target at 3.6 angstrom resolution

Summary for 8IP0

• Entry DOI: 10.2210/pdb8ip0/pdb
• EMDB information: 35629
• Descriptor: Type I-MYXAN CRISPR-associated protein Cmx8, Type I-MYXAN CRISPR-associated protein Cas5/Cmx5/DevS, Fruiting body developmental protein R-like protein, ... (8 entities in total)
• Functional Keywords: type i-b, crispr-cas, cascade, rna binding protein/rna/dna, rna binding protein-rna-dna complex
• Biological source: Synechocystis sp. PCC 6714 (Aphanocapsa sp. (strain PCC 6714)); More
• Total number of polymer chains: 16
• Total formula weight: 404717.28

Authors

Xiao, Y.,Lu, M.,Yu, C.,Zhang, Y. (deposition date: 2023-03-13, release date: 2024-03-20, Last modification date: 2024-05-29)

• Primary citation: Lu, M.,Yu, C.,Zhang, Y.,Ju, W.,Ye, Z.,Hua, C.,Mao, J.,Hu, C.,Yang, Z.,Xiao, Y.; Structure and genome editing of type I-B CRISPR-Cas.; Nat Commun, 15:4126-4126, 2024; PubMed: 38750051; DOI: 10.1038/s41467-024-48598-2

Experimental method

ELECTRON MICROSCOPY (3.6 Å)