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1I37
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BU of 1i37 by Molmil
CRYSTAL STRUCTURE OF THE RAT ANDROGEN RECEPTOR LIGAND BINDING DOMAIN COMPLEX WITH DIHYDROTESTOSTERONE
Descriptor: 5-ALPHA-DIHYDROTESTOSTERONE, ANDROGEN RECEPTOR
Authors:Sack, J.S.
Deposit date:2001-02-13
Release date:2001-03-21
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone.
Proc.Natl.Acad.Sci.USA, 98, 2001
6IXL
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BU of 6ixl by Molmil
Crystal structure of isocitrate dehydrogenase from Ostreococcus tauri
Descriptor: GLYCEROL, Isocitrate dehydrogenase, SULFATE ION
Authors:Zhu, G.P, Tang, W.G, Wang, P.
Deposit date:2018-12-11
Release date:2019-12-18
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of NAD + -linked isocitrate dehydrogenase from the green alga Ostreococcus tauri and its evolutionary relationship with eukaryotic NADP + -linked homologs.
Arch.Biochem.Biophys., 708, 2021
6IXN
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BU of 6ixn by Molmil
Crystal structure of isocitrate dehydrogenase from Ostreococcus tauri in complex with NAD+ and citrate
Descriptor: CITRATE ANION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Zhu, G.P, Tang, W.G, Wang, P.
Deposit date:2018-12-11
Release date:2019-12-18
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Crystal structures of NAD + -linked isocitrate dehydrogenase from the green alga Ostreococcus tauri and its evolutionary relationship with eukaryotic NADP + -linked homologs.
Arch.Biochem.Biophys., 708, 2021
6UV8
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BU of 6uv8 by Molmil
Crystal structure of a far-red cyanobacteriochrome photoreceptor at room temperature
Descriptor: Multi-sensor signal transduction histidine kinase, PHYCOCYANOBILIN
Authors:Yang, X, Ren, Z, Bandara, S.
Deposit date:2019-11-01
Release date:2020-11-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.701 Å)
Cite:Crystal structure of a far-red-sensing cyanobacteriochrome reveals an atypical bilin conformation and spectral tuning mechanism.
Proc.Natl.Acad.Sci.USA, 118, 2021
1S4U
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BU of 1s4u by Molmil
Crystal Structure analysis of the beta-propeller protein Ski8p
Descriptor: Antiviral protein SKI8
Authors:Cheng, Z, Song, H.
Deposit date:2004-01-18
Release date:2004-12-28
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of Ski8p, a WD-repeat protein with dual roles in mRNA metabolism and meiotic recombination
Protein Sci., 13, 2004
8I8Y
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BU of 8i8y by Molmil
A mutant of the C-terminal complex of proteins 4.1G and NuMA
Descriptor: Engineered protein
Authors:Hu, X.
Deposit date:2023-02-06
Release date:2023-04-19
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Combined prediction and design reveals the target recognition mechanism of an intrinsically disordered protein interaction domain.
Proc.Natl.Acad.Sci.USA, 120, 2023
6IXT
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BU of 6ixt by Molmil
Crystal structure of isocitrate dehydrogenase from Ostreococcus tauri in complex with NAD+ and Mg2+
Descriptor: GLYCEROL, Isocitrate dehydrogenase, MAGNESIUM ION, ...
Authors:Zhu, G.P, Tang, W.G, Wang, P.
Deposit date:2018-12-12
Release date:2019-12-18
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structures of NAD + -linked isocitrate dehydrogenase from the green alga Ostreococcus tauri and its evolutionary relationship with eukaryotic NADP + -linked homologs.
Arch.Biochem.Biophys., 708, 2021
5J8J
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BU of 5j8j by Molmil
A histone deacetylase from Saccharomyces cerevisiae
Descriptor: Histone deacetylase HDA1
Authors:Zhu, Y, Shen, H, Li, X, Teng, M.
Deposit date:2016-04-07
Release date:2017-04-19
Method:X-RAY DIFFRACTION (2.716 Å)
Cite:Structural and histone binding ability characterization of the ARB2 domain of a histone deacetylase Hda1 from Saccharomyces cerevisiae.
Sci Rep, 6, 2016
7KLZ
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BU of 7klz by Molmil
Structure of SPOP MATH domain in complex with a Geminin peptide
Descriptor: Geminin peptide, PHOSPHATE ION, Speckle-type POZ protein
Authors:Cui, G, Botuyan, M.V, Mer, G.
Deposit date:2020-11-01
Release date:2021-08-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition.
Nat Commun, 12, 2021
6VIE
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BU of 6vie by Molmil
Structure of caspase-1 in complex with gasdermin D
Descriptor: Caspase-1 subunit p10, Caspase-1 subunit p20, Gasdermin-D
Authors:Liu, Z, Xiao, T.S.
Deposit date:2020-01-13
Release date:2020-07-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage.
Immunity, 53, 2020
2BBT
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BU of 2bbt by Molmil
Human deltaF508 NBD1 with two solublizing mutations.
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
Authors:Lewis, H.A, Kearins, M.C, Conners, K, Zhao, X, Lu, F, Sauder, J.M, Emtage, S.
Deposit date:2005-10-17
Release date:2005-11-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry.
J.Mol.Biol., 396, 2010
6W35
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BU of 6w35 by Molmil
A new Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-fluoranyl-~{N}-[(2~{R})-1-[1-(2~{H}-indazol-5-yl)-3-methyl-2,4-bis(oxidanylidene)-1,3,8-triazaspiro[4.5]decan-8-yl]-3-methyl-1-oxidanylidene-butan-2-yl]-5-(trifluoromethyl)benzamide, CALCIUM ION, ...
Authors:Cuozzo, J.W.
Deposit date:2020-03-09
Release date:2020-07-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry.
J.Med.Chem., 63, 2020
6VWU
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BU of 6vwu by Molmil
X-ray structure of ALKS 4230, a fusion of circularly permuted human Interleukin-2 and Interleukin-2 Receptor alpha
Descriptor: Interleukin-2,Interleukin-2 receptor subunit alpha
Authors:Losey, H.C.
Deposit date:2020-02-20
Release date:2020-04-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:ALKS 4230: a novel engineered IL-2 fusion protein with an improved cellular selectivity profile for cancer immunotherapy.
J Immunother Cancer, 8, 2020
8J1X
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BU of 8j1x by Molmil
A near-infrared fluorescent protein of de novo backbone design
Descriptor: near-infrared fluorescent protein
Authors:Hu, X, Xu, Y.
Deposit date:2023-04-13
Release date:2023-10-04
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Using Protein Design and Directed Evolution to Monomerize a Bright Near-Infrared Fluorescent Protein.
Acs Synth Biol, 13, 2024
8J1W
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BU of 8j1w by Molmil
A near-infrared fluorescent protein of de novo backbone design
Descriptor: near-infrared fluorescent protein
Authors:Hu, X, Xu, Y.
Deposit date:2023-04-13
Release date:2023-10-04
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Using Protein Design and Directed Evolution to Monomerize a Bright Near-Infrared Fluorescent Protein.
Acs Synth Biol, 13, 2024
2BBO
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BU of 2bbo by Molmil
Human NBD1 with Phe508
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
Authors:Lewis, H.A, Kearins, M.C, Conners, K, Zhao, X, Lu, F, Sauder, J.M, Emtage, S.
Deposit date:2005-10-17
Release date:2005-11-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry.
J.Mol.Biol., 396, 2010
3V45
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BU of 3v45 by Molmil
Crystal Structure of de novo designed serine hydrolase OSH55, Northeast Structural Genomics Consortium Target OR130
Descriptor: CHLORIDE ION, SODIUM ION, Serine hydrolase OSH55
Authors:Kuzin, A, Su, M, Seetharaman, J, Maglaqui, M, Xiao, R, Kohan, E, Rajagopalan, S, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-12-14
Release date:2012-01-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Design of activated serine-containing catalytic triads with atomic-level accuracy.
Nat.Chem.Biol., 10, 2014
5SZC
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BU of 5szc by Molmil
Structure of human Dpf3 double-PHD domain bound to histone H3 tail peptide with monomethylated K4 and acetylated K14
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Histone H3 tail peptide, ZINC ION, ...
Authors:Singh, N, Local, A, Shiau, A, Ren, B, Corbett, K.D.
Deposit date:2016-08-13
Release date:2017-08-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.193 Å)
Cite:Identification of H3K4me1-associated proteins at mammalian enhancers.
Nat. Genet., 50, 2018
5SZB
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BU of 5szb by Molmil
Structure of human Dpf3 double-PHD domain bound to histone H3 tail peptide with acetylated K14
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Histone H3 tail peptide, ZINC ION, ...
Authors:Singh, N, Local, A, Shiau, A, Ren, B, Corbett, K.D.
Deposit date:2016-08-13
Release date:2017-08-16
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Identification of H3K4me1-associated proteins at mammalian enhancers.
Nat. Genet., 50, 2018
6WER
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BU of 6wer by Molmil
DENV2 NS1 in complex with neutralizing 2B7 Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B7 Fab heavy chain, 2B7 Fab light chain, ...
Authors:Akey, D.L, Smith, J.L.
Deposit date:2020-04-02
Release date:2020-12-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.96 Å)
Cite:Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction.
Science, 371, 2021
2BBS
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BU of 2bbs by Molmil
Human deltaF508 NBD1 with three solubilizing mutations
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, MAGNESIUM ION
Authors:Lewis, H.A, Kearins, M.C, Conners, K, Zhao, X, Lu, F, Sauder, J.M, Emtage, S.
Deposit date:2005-10-17
Release date:2005-11-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry.
J.Mol.Biol., 396, 2010
7D3W
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BU of 7d3w by Molmil
Non-specific and specific interactions work cooperatively to promote cytidine deamination catalyzed by APOBEC3A
Descriptor: DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*TP*T)-3'), DNA dC->dU-editing enzyme APOBEC-3A, ZINC ION
Authors:Cao, C, Liu, Y, Lan, W.
Deposit date:2020-09-21
Release date:2021-10-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Two different kinds of interaction modes of deaminase APOBEC3A with single-stranded DNA in solution detected by nuclear magnetic resonance.
Protein Sci., 31, 2022
7D3X
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BU of 7d3x by Molmil
Non-specific and specific interactions work cooperatively to promote cytidine deamination catalyzed by APOBEC3A
Descriptor: DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*TP*T)-3'), DNA dC->dU-editing enzyme APOBEC-3A, ZINC ION
Authors:Cao, C, Liu, Y.
Deposit date:2020-09-21
Release date:2021-10-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Two different kinds of interaction modes of deaminase APOBEC3A with single-stranded DNA in solution detected by nuclear magnetic resonance.
Protein Sci., 31, 2022
5VAG
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BU of 5vag by Molmil
Crystal structure of H7-specific antibody m826 in complex with the HA1 domain of hemagglutinin from H7N9 influenza virus
Descriptor: 1,2-ETHANEDIOL, Heavy chain of antibody m826, Hemagglutinin, ...
Authors:Song, H, Ying, T, Ji, X.
Deposit date:2017-03-26
Release date:2017-12-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Potent Germline-like Human Monoclonal Antibody Targets a pH-Sensitive Epitope on H7N9 Influenza Hemagglutinin.
Cell Host Microbe, 22, 2017
1F6B
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BU of 1f6b by Molmil
CRYSTAL STRUCTURE OF SAR1-GDP COMPLEX
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SAR1, ...
Authors:Huang, M, Wilson, I.A, Balch, W.E.
Deposit date:2000-06-21
Release date:2002-01-09
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of Sar1-GDP at 1.7 A resolution and the role of the NH2 terminus in ER export.
J.Cell Biol., 155, 2001

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