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7DQ4
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BU of 7dq4 by Molmil
Cryo-EM structure of CAR triggered Coxsackievirus B1 A-particle
Descriptor: VP2, VP3, Virion protein 1
Authors:Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q.
Deposit date:2020-12-22
Release date:2021-05-05
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
7DPG
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BU of 7dpg by Molmil
Cryo-EM structure of Coxsackievirus B1 empty particle
Descriptor: VP2, VP3, Virion protein 1
Authors:Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q, Xia, N.
Deposit date:2020-12-18
Release date:2021-05-05
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
7DPZ
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BU of 7dpz by Molmil
Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR
Descriptor: Capsid protein VP4, Coxsackievirus and adenovirus receptor, VP2, ...
Authors:Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q.
Deposit date:2020-12-22
Release date:2021-05-05
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
7DQ1
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BU of 7dq1 by Molmil
Cryo-EM structure of Coxsackievirus B1 virion in complex with CAR at physiological temperature
Descriptor: Capsid protein VP4, Coxsackievirus and adenovirus receptor, VP2, ...
Authors:Li, S, Zhu, R, Xu, L, Cheng, T, Zheng, Q.
Deposit date:2020-12-22
Release date:2021-05-05
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structures reveal the molecular basis of receptor-initiated coxsackievirus uncoating.
Cell Host Microbe, 29, 2021
6IIO
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BU of 6iio by Molmil
Cryo-EM structure of CV-A10 native empty particle
Descriptor: VP0, VP1, VP3
Authors:Chen, J.H, Ye, X.H, Cong, Y, Huang, Z.
Deposit date:2018-10-07
Release date:2018-11-07
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Coxsackievirus A10 atomic structure facilitating the discovery of a broad-spectrum inhibitor against human enteroviruses.
Cell Discov, 5, 2019
6JHO
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BU of 6jho by Molmil
The complex crystal structure of Cagbeta with CagZ revealed a novel regulatory mechanism for T4SS coupling ATPase in Helicobacter pylori
Descriptor: Cag pathogenicity island protein (Cag5), Cag pathogenicity island protein (Cag6)
Authors:Wu, X, Zhao, Y, Sun, L, Ye, X, Jiang, M, Wang, Q, Wang, Q, Wu, Y.
Deposit date:2019-02-18
Release date:2020-02-19
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The complex crystal structure of Cagbeta with CagZ revealed a novel regulatory mechanism in VirD4 coupling ATPase
To Be Published
6IIJ
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BU of 6iij by Molmil
Cryo-EM structure of CV-A10 mature virion
Descriptor: SPHINGOSINE, VP1, VP2, ...
Authors:Chen, J.H, Ye, X.H, Cong, Y, Huang, Z.
Deposit date:2018-10-06
Release date:2018-11-07
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Coxsackievirus A10 atomic structure facilitating the discovery of a broad-spectrum inhibitor against human enteroviruses.
Cell Discov, 5, 2019
5GS4
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BU of 5gs4 by Molmil
Crystal structure of estrogen receptor alpha in complex with a stabilized peptide antagonist
Descriptor: ARG-IAS-ILE-LEU-DNP-ARG-LEU-LEU-GLN, ESTRADIOL, Estrogen receptor, ...
Authors:Xie, M, Wang, T, Li, Z.-G.
Deposit date:2016-08-13
Release date:2017-08-30
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of Inhibition of ER alpha-Coactivator Interaction by High-Affinity N-Terminus Isoaspartic Acid Tethered Helical Peptides
J. Med. Chem., 60, 2017
5GTR
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BU of 5gtr by Molmil
estrogen receptor alpha in complex with a stabilized peptide antagonist 6
Descriptor: ARG-IAS-ILE-0JY-DPP-ARG-0JY-0JY-GLN-NH2, ESTRADIOL, Estrogen receptor
Authors:Xie, M, Wang, T, Li, Z.-G.
Deposit date:2016-08-23
Release date:2017-08-30
Last modified:2017-12-20
Method:X-RAY DIFFRACTION (2.804 Å)
Cite:Structural Basis of Inhibition of ER alpha-Coactivator Interaction by High-Affinity N-Terminus Isoaspartic Acid Tethered Helical Peptides
J. Med. Chem., 60, 2017
2FMX
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BU of 2fmx by Molmil
An open conformation of switch I revealed by Sar1-GDP crystal structure at low Mg(2+)
Descriptor: GTP-binding protein SAR1b, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Rao, Y, Bian, C, Yuan, C, Li, Y, Huang, M.
Deposit date:2006-01-10
Release date:2006-09-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:An open conformation of switch I revealed by Sar1-GDP crystal structure at low Mg(2+)
Biochem.Biophys.Res.Commun., 348, 2006
6KXG
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BU of 6kxg by Molmil
Crystal structure of caspase-11-CARD
Descriptor: caspase-11-CARD
Authors:Liu, M.Z.Y, Jin, T.C.
Deposit date:2019-09-11
Release date:2020-09-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.805 Å)
Cite:Crystal structure of caspase-11 CARD provides insights into caspase-11 activation.
Cell Discov, 6, 2020
8QBJ
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BU of 8qbj by Molmil
Structure of mBaoJin at pH 4.6
Descriptor: CHLORIDE ION, mBaoJin
Authors:Samygina, V.R, Vlaskina, A.V, Gabdulkhakov, A, Subach, O.M, Subach, F.V.
Deposit date:2023-08-24
Release date:2023-12-27
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Bright and stable monomeric green fluorescent protein derived from StayGold.
Nat.Methods, 21, 2024
8QDD
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BU of 8qdd by Molmil
Structure of mBaoJin at pH 8.5
Descriptor: CHLORIDE ION, SULFATE ION, mBaoJin
Authors:Samygina, V.R, Vlaskina, A.V, Gabdulkhakov, A, Subach, O.M, Subach, F.V.
Deposit date:2023-08-28
Release date:2023-12-27
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Bright and stable monomeric green fluorescent protein derived from StayGold.
Nat.Methods, 21, 2024
8Q79
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BU of 8q79 by Molmil
Structure of mBaoJin at pH 6.5
Descriptor: CHLORIDE ION, mBaoJin
Authors:Samygina, V.R, Subach, O.M, Vlaskina, A.V, Nikolaeva, A.Y, Borshchevsky, V, Qin, W, Subach, F.V.
Deposit date:2023-08-15
Release date:2023-12-27
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Bright and stable monomeric green fluorescent protein derived from StayGold.
Nat.Methods, 21, 2024
3L15
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BU of 3l15 by Molmil
Human Tead2 transcriptional factor
Descriptor: GLYCEROL, Transcriptional enhancer factor TEF-4
Authors:Tomchick, D.R, Luo, X, Tian, W.
Deposit date:2009-12-10
Release date:2010-04-07
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional analysis of the YAP-binding domain of human TEAD2.
Proc.Natl.Acad.Sci.USA, 107, 2010
8UN5
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BU of 8un5 by Molmil
KRAS-G13D-GDP in complex with Cpd38 ((E)-1-((3S)-4-(7-(6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-6-chloro-8-fluoro-2-(((S)-2-methylenetetrahydro-1H-pyrrolizin-7a(5H)-yl)methoxy)quinazolin-4-yl)-3-methylpiperazin-1-yl)-3-(1,2,3,4-tetrahydroisoquinolin-8-yl)prop-2-en-1-one)
Descriptor: (2E)-1-{(3S)-4-[(7M)-7-[6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl]-6-chloro-8-fluoro-2-{[(4R,7aS)-2-methylidenetetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}quinazolin-4-yl]-3-methylpiperazin-1-yl}-3-(1,2,3,4-tetrahydroisoquinolin-8-yl)prop-2-en-1-one, GLYCEROL, GTPase KRas, ...
Authors:Ultsch, M.H.
Deposit date:2023-10-18
Release date:2023-12-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors.
Acs Med.Chem.Lett., 15, 2024
8UN3
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BU of 8un3 by Molmil
KRAS-G13D-GDP in complex with Cpd5 (1-((S)-10-(6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl)-11-chloro-7-(((2S,4R)-4-fluoro-1-methylpyrrolidin-2-yl)methoxy)-3,4,13,13a-tetrahydropyrazino[2',1':3,4][1,4]oxazepino[5,6,7-de]quinazolin-2(1H)-yl)prop-2-en-1-one)
Descriptor: 1,2-ETHANEDIOL, 1-[(5M,8aS,13R)-5-[6-amino-4-methyl-3-(trifluoromethyl)pyridin-2-yl]-6-chloro-2-{[(2S,4R)-4-fluoro-1-methylpyrrolidin-2-yl]methoxy}-8a,9,11,12-tetrahydropyrazino[2',1':3,4][1,4]oxazepino[5,6,7-de]quinazolin-10(8H)-yl]prop-2-en-1-one, CHLORIDE ION, ...
Authors:Ultsch, M.H.
Deposit date:2023-10-18
Release date:2023-12-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors.
Acs Med.Chem.Lett., 15, 2024
5XS5
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BU of 5xs5 by Molmil
Structure of Coxsackievirus A6 (CVA6) virus procapsid particle
Descriptor: Genome polyprotein
Authors:Zheng, Q.B, He, M.Z, Xu, L.F, Yu, H, Cheng, T, Li, S.W.
Deposit date:2017-06-12
Release date:2017-09-27
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody
Nat Commun, 8, 2017
5YHQ
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BU of 5yhq by Molmil
Cryo-EM Structure of CVA6 VLP
Descriptor: Capsid protein VP1, Capsid protein VP3, capsid protein VP0
Authors:Chen, J, Zhang, C, Huang, Z, Cong, Y.
Deposit date:2017-09-29
Release date:2017-10-25
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A 3.0-Angstrom Resolution Cryo-Electron Microscopy Structure and Antigenic Sites of Coxsackievirus A6-Like Particles.
J. Virol., 92, 2018
7M1C
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BU of 7m1c by Molmil
Crystal structure of the HCMV pentamer-specific antibody 1-32
Descriptor: 1-32 Fab Heavy Chain, 1-32 Fab Light Chain
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2021-03-12
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7LYV
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BU of 7lyv by Molmil
Crystal structure of the HCMV pentamer-specific antibody 1-103
Descriptor: 1-103 Fab Heavy Chain, 1-103 Fab Light Chain
Authors:Wrapp, D, Jones, H.G, McLellan, J.S.
Deposit date:2021-03-08
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7KBB
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BU of 7kbb by Molmil
Cryo-EM structure of the HCMV pentamer bound by Fabs 2-18 and 8I21
Descriptor: 2-18 Fab Heavy Chain, 2-18 Fab Light Chain, 8I21 Fab Heavy Chain, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2020-10-01
Release date:2021-08-11
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (4.02 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
7KBA
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BU of 7kba by Molmil
Crystal structure of the HCMV pentamer-specific Fab 2-18
Descriptor: 2-18 Fab Heavy Chain, 2-18 Fab Light Chain
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2020-10-01
Release date:2021-08-11
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022
5XS4
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BU of 5xs4 by Molmil
Structure of Coxsackievirus A6 (CVA6) virus A-particle
Descriptor: Genome polyprotein
Authors:Zheng, Q.B, He, M.Z, Xu, L.F, Yu, H, Li, S.W, Cheng, T.
Deposit date:2017-06-12
Release date:2017-09-27
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody
Nat Commun, 8, 2017
7M22
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BU of 7m22 by Molmil
Cryo-EM structure of the HCMV pentamer bound by human neuropilin 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein UL130, ...
Authors:Wrapp, D, McLellan, J.S.
Deposit date:2021-03-15
Release date:2021-08-11
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies.
Sci Adv, 8, 2022

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