Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1H1R
DownloadVisualize
BU of 1h1r by Molmil
Structure of human Thr160-phospho CDK2/cyclin A complexed with the inhibitor NU6086
Descriptor: 6-CYCLOHEXYLMETHOXY-2-(3'-CHLOROANILINO) PURINE, CELL DIVISION PROTEIN KINASE 2, CYCLIN A2
Authors:Davies, T.G, Noble, M.E.M, Endicott, J.A, Johnson, L.N.
Deposit date:2002-07-21
Release date:2002-09-19
Last modified:2019-10-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor.
Nat. Struct. Biol., 9, 2002
3TN8
DownloadVisualize
BU of 3tn8 by Molmil
CDK9/cyclin T in complex with CAN508
Descriptor: 4-[(E)-(3,5-DIAMINO-1H-PYRAZOL-4-YL)DIAZENYL]PHENOL, Cyclin-T1, Cyclin-dependent kinase 9, ...
Authors:Baumli, S, Hole, A.J, Endicott, J.E.
Deposit date:2011-09-01
Release date:2012-02-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:The CDK9 C-helix Exhibits Conformational Plasticity That May Explain the Selectivity of CAN508.
Acs Chem.Biol., 7, 2012
3TNW
DownloadVisualize
BU of 3tnw by Molmil
Structure of CDK2/cyclin A in complex with CAN508
Descriptor: 4-[(E)-(3,5-DIAMINO-1H-PYRAZOL-4-YL)DIAZENYL]PHENOL, Cyclin-A2, Cyclin-dependent kinase 2, ...
Authors:Baumli, S, Hole, A.J, Endicott, J.A.
Deposit date:2011-09-02
Release date:2012-02-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The CDK9 C-helix Exhibits Conformational Plasticity That May Explain the Selectivity of CAN508.
Acs Chem.Biol., 7, 2012
3TNI
DownloadVisualize
BU of 3tni by Molmil
structure of CDK9/cyclin T F241L
Descriptor: Cyclin-T1, Cyclin-dependent kinase 9
Authors:Baumli, S, Hole, A.J, Endicott, J.A.
Deposit date:2011-09-01
Release date:2012-02-15
Last modified:2012-05-30
Method:X-RAY DIFFRACTION (3.234 Å)
Cite:The CDK9 C-helix Exhibits Conformational Plasticity That May Explain the Selectivity of CAN508.
Acs Chem.Biol., 7, 2012
3TNH
DownloadVisualize
BU of 3tnh by Molmil
CDK9/cyclin T in complex with CAN508
Descriptor: 4-[(E)-(3,5-DIAMINO-1H-PYRAZOL-4-YL)DIAZENYL]PHENOL, Cyclin-T1, Cyclin-dependent kinase 9
Authors:Baumli, S, Hole, A.J, Endicott, J.A.
Deposit date:2011-09-01
Release date:2012-02-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.202 Å)
Cite:The CDK9 C-helix Exhibits Conformational Plasticity That May Explain the Selectivity of CAN508.
Acs Chem.Biol., 7, 2012
3TIM
DownloadVisualize
BU of 3tim by Molmil
THE CRYSTAL STRUCTURE OF THE "OPEN" AND THE "CLOSED" CONFORMATION OF THE FLEXIBLE LOOP OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE
Descriptor: TRIOSEPHOSPHATE ISOMERASE
Authors:Wierenga, R.K.
Deposit date:1990-05-15
Release date:1991-10-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of the "open" and the "closed" conformation of the flexible loop of trypanosomal triosephosphate isomerase.
Proteins, 10, 1991
4EC8
DownloadVisualize
BU of 4ec8 by Molmil
Structure of full length CDK9 in complex with cyclinT and DRB
Descriptor: Cyclin-T1, Cyclin-dependent kinase 9
Authors:Baumli, S, Hole, A.J, Endicott, J.A.
Deposit date:2012-03-26
Release date:2012-09-12
Last modified:2014-10-22
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:The CDK9 tail determines the reaction pathway of positive transcription elongation factor b.
Structure, 20, 2012
4EC9
DownloadVisualize
BU of 4ec9 by Molmil
Crystal structure of full-length cdk9 in complex with cyclin t
Descriptor: Cyclin-T1, Cyclin-dependent kinase 9
Authors:Baumli, S, Hole, A.J, Endicott, J.A.
Deposit date:2012-03-26
Release date:2012-09-12
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:The CDK9 tail determines the reaction pathway of positive transcription elongation factor b.
Structure, 20, 2012
1E2T
DownloadVisualize
BU of 1e2t by Molmil
Arylamine N-acetyltransferase (NAT) from Salmonella typhimurium
Descriptor: N-HYDROXYARYLAMINE O-ACETYLTRANSFERASE
Authors:Sinclair, J.C, Sandy, J, Delgoda, R, Sim, E, Noble, M.E.M.
Deposit date:2000-05-24
Release date:2000-07-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of Arylamine N-Acetyltransferase Reveals a Catalytic Triad
Nat.Struct.Biol., 7, 2000
1AG1
DownloadVisualize
BU of 1ag1 by Molmil
MONOHYDROGEN PHOSPHATE BINDING TO TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE
Descriptor: PHOSPHATE ION, TRIOSEPHOSPHATE ISOMERASE
Authors:Verlinde, C.L.M.J, Hol, W.G.J.
Deposit date:1997-03-28
Release date:1997-06-16
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Anion binding at the active site of trypanosomal triosephosphate isomerase. Monohydrogen phosphate does not mimic sulphate.
Eur.J.Biochem., 198, 1991
1B9K
DownloadVisualize
BU of 1b9k by Molmil
ALPHA-ADAPTIN APPENDAGE DOMAIN, FROM CLATHRIN ADAPTOR AP2
Descriptor: PROTEIN (ALPHA-ADAPTIN APPENDAGE DOMAIN)
Authors:Owen, D.J, Evans, P.R.
Deposit date:1999-02-11
Release date:1999-07-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain.
Cell(Cambridge,Mass.), 97, 1999
5TIM
DownloadVisualize
BU of 5tim by Molmil
REFINED 1.83 ANGSTROMS STRUCTURE OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE, CRYSTALLIZED IN THE PRESENCE OF 2.4 M-AMMONIUM SULPHATE. A COMPARISON WITH THE STRUCTURE OF THE TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE-GLYCEROL-3-PHOSPHATE COMPLEX
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, SULFATE ION, TRIOSEPHOSPHATE ISOMERASE
Authors:Wierenga, R.K, Hol, W.G.J.
Deposit date:1991-04-23
Release date:1992-10-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Refined 1.83 A structure of trypanosomal triosephosphate isomerase crystallized in the presence of 2.4 M-ammonium sulphate. A comparison with the structure of the trypanosomal triosephosphate isomerase-glycerol-3-phosphate complex.
J.Mol.Biol., 220, 1991
1AWO
DownloadVisualize
BU of 1awo by Molmil
THE SOLUTION NMR STRUCTURE OF ABL SH3 AND ITS RELATIONSHIP TO SH2 IN THE SH(32) CONSTRUCT, 20 STRUCTURES
Descriptor: ABL TYROSINE KINASE
Authors:Cowburn, D.
Deposit date:1997-10-03
Release date:1998-01-28
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The solution structure of Abl SH3, and its relationship to SH2 in the SH(32) construct.
Structure, 3, 1995
1TMH
DownloadVisualize
BU of 1tmh by Molmil
MODULAR MUTAGENESIS OF A TIM-BARREL ENZYME: THE CRYSTAL STRUCTURE OF A CHIMERIC E. COLI TIM HAVING THE EIGHTH (BETA-ALPHA)-UNIT REPLACED BY THE EQUIVALENT UNIT OF CHICKEN TIM
Descriptor: SULFATE ION, TRIOSEPHOSPHATE ISOMERASE
Authors:Radha Kishan, K.V, Zeelen, J.Ph, Wierenga, R.K.
Deposit date:1994-03-22
Release date:1994-06-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Modular mutagenesis of a TIM-barrel enzyme: the crystal structure of a chimeric E. coli TIM having the eighth beta alpha-unit replaced by the equivalent unit of chicken TIM.
Protein Eng., 7, 1994
1TPF
DownloadVisualize
BU of 1tpf by Molmil
COMPARISON OF THE STRUCTURES AND THE CRYSTAL CONTACTS OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE IN FOUR DIFFERENT CRYSTAL FORMS
Descriptor: DIMETHYL SULFOXIDE, TRIOSEPHOSPHATE ISOMERASE
Authors:Radha Kishan, K.V, Zeelen, J.Ph, Wierenga, R.K.
Deposit date:1994-02-28
Release date:1994-05-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Comparison of the structures and the crystal contacts of trypanosomal triosephosphate isomerase in four different crystal forms.
Protein Sci., 3, 1994
1JKW
DownloadVisualize
BU of 1jkw by Molmil
STRUCTURE OF CYCLIN MCS2
Descriptor: CYCLIN H
Authors:Andersen, G, Poterszman, A, Moras, D, Thierry, J.C.
Deposit date:1996-10-11
Release date:1997-01-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal structure of human cyclin H.
FEBS Lett., 397, 1996
4CTM
DownloadVisualize
BU of 4ctm by Molmil
Glucopyranosylidene-spiro-iminothiazolidinone, a New Bicyclic Ring System: Synthesis, Derivatization, and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetic and Crystallographic Methods
Descriptor: (5R,7R,8S,9S,10R)-8,9,10-trihydroxy-7-(hydroxymethyl)-2-imino-6-oxa-1-thia-3-azaspiro[4.5]decan-4-one, GLYCOGEN PHOSPHORYLASE, MUSCLE FORM, ...
Authors:Alexacou, K.M, Papakonstantinou, M, Leonidas, D.D, Zographos, S.E, Chrysina, E.D.
Deposit date:2014-03-15
Release date:2014-08-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Glucopyranosylidene-Spiro-Iminothiazolidinone, a New Bicyclic Ring System: Synthesis, Derivatization, and Evaluation for Inhibition of Glycogen Phosphorylase by Enzyme Kinetic and Crystallographic Methods.
Bioorg.Med.Chem., 22, 2014
4CTN
DownloadVisualize
BU of 4ctn by Molmil
Glucopyranosylidene-spiro-iminothiazolidinone, a New Bicyclic Ring System: Synthesis, Derivatization, and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetic and Crystallographic Methods
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DIMETHYL SULFOXIDE, GLYCOGEN PHOSPHORYLASE, ...
Authors:Alexacou, K.M, Papakonstantinou, M, Leonidas, D.D, Zographos, S.E, Chrysina, E.D.
Deposit date:2014-03-15
Release date:2014-08-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Glucopyranosylidene-Spiro-Iminothiazolidinone, a New Bicyclic Ring System: Synthesis, Derivatization, and Evaluation for Inhibition of Glycogen Phosphorylase by Enzyme Kinetic and Crystallographic Methods.
Bioorg.Med.Chem., 22, 2014
4CTO
DownloadVisualize
BU of 4cto by Molmil
Glucopyranosylidene-spiro-iminothiazolidinone, a New Bicyclic Ring System: Synthesis, Derivatization, and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetic and Crystallographic Methods
Descriptor: GLYCOGEN PHOSPHORYLASE, MUSCLE FORM, N-[(2Z,5R,7R,8S,9S,10R)-8,9,10-trihydroxy-7-(hydroxymethyl)-4-oxo-6-oxa-1-thia-3-azaspiro[4.5]dec-2-ylidene]benzamide, ...
Authors:Alexacou, K.M, Papakonstantinou, M, Leonidas, D.D, Zographos, S.E, Chrysina, E.D.
Deposit date:2014-03-15
Release date:2014-08-06
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Glucopyranosylidene-Spiro-Iminothiazolidinone, a New Bicyclic Ring System: Synthesis, Derivatization, and Evaluation for Inhibition of Glycogen Phosphorylase by Enzyme Kinetic and Crystallographic Methods.
Bioorg.Med.Chem., 22, 2014
1NYF
DownloadVisualize
BU of 1nyf by Molmil
NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE, MINIMIZED AVERAGE (PROBMAP) STRUCTURE
Descriptor: FYN
Authors:Morton, C.J, Pugh, D.J.R, Campbell, I.D.
Deposit date:1996-04-22
Release date:1996-11-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure and peptide binding of the SH3 domain from human Fyn.
Structure, 4, 1996
1NYG
DownloadVisualize
BU of 1nyg by Molmil
NMR STUDY OF THE SH3 DOMAIN FROM FYN PROTO-ONCOGENE TYROSINE KINASE, FAMILY OF 20 STRUCTURES
Descriptor: FYN
Authors:Morton, C.J, Pugh, D.J.R, Campbell, I.D.
Deposit date:1996-04-22
Release date:1996-11-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure and peptide binding of the SH3 domain from human Fyn.
Structure, 4, 1996
1QGE
DownloadVisualize
BU of 1qge by Molmil
NEW CRYSTAL FORM OF PSEUDOMONAS GLUMAE (FORMERLY CHROMOBACTERIUM VISCOSUM ATCC 6918) LIPASE
Descriptor: CALCIUM ION, PROTEIN (TRIACYLGLYCEROL HYDROLASE)
Authors:Lang, D.A, Stadler, P, Kovacs, A, Paltauf, F, Dijkstra, B.W.
Deposit date:1999-04-27
Release date:1999-05-06
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and Kinetic Investigations of Enantiomeric Binding Mode of Subclass I Lipases from the Family of Pseudomonadaceae
To be Published
1FS4
DownloadVisualize
BU of 1fs4 by Molmil
Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based drug design
Descriptor: 1-DEOXY-1-METHOXYCARBAMIDO-BETA-D-GLUCO-2-HEPTULOPYRANOSONAMIDE, GLYCOGEN PHOSPHORYLASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Watson, K.A, Tsitsanou, K.E, Gregoriou, M, Zographos, S.E, Skamnaki, V.T, Oikonomakos, N.G, Fleet, G.W, Johnson, L.N.
Deposit date:2000-09-08
Release date:2000-10-04
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005
1FU4
DownloadVisualize
BU of 1fu4 by Molmil
STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
Descriptor: GLYCOGEN PHOSPHORYLASE, N-[(5S,7R,8S,9S,10R)-8,9,10-trihydroxy-7-(hydroxymethyl)-2,4-dioxo-6-oxa-1,3-diazaspiro[4.5]dec-3-yl]acetamide, PYRIDOXAL-5'-PHOSPHATE
Authors:Watson, K.A, Tsitsanou, K.E, Gregoriou, M, Zographos, S.E, Skamnaki, V.T, Oikonomakos, N.G, Fleet, G.W, Johnson, L.N.
Deposit date:2000-09-14
Release date:2000-10-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005
1FTW
DownloadVisualize
BU of 1ftw by Molmil
STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
Descriptor: (5S,7R,8S,9S,10R)-3,8,9,10-tetrahydroxy-7-(hydroxymethyl)-6-oxa-1,3-diazaspiro[4.5]decane-2,4-dione, GLYCOGEN PHOSPHORYLASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Watson, K.A, Tsitsanou, K.E, Gregoriou, M, Zographos, S.E, Skamnaki, V.T, Oikonomakos, N.G, Fleet, G.W, Johnson, L.N.
Deposit date:2000-09-13
Release date:2000-10-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
Proteins, 61, 2005

220472

건을2024-05-29부터공개중

PDB statisticsPDBj update infoContact PDBjnumon