4EC8

Structure of full length CDK9 in complex with cyclinT and DRB

Summary for 4EC8

• Entry DOI: 10.2210/pdb4ec8/pdb
• Related: 3MY1 4EC9
• Descriptor: Cyclin-dependent kinase 9, Cyclin-T1 (2 entities in total)
• Functional Keywords: cyclin dependend kinase, cyclin, transferase-protein binding complex, transferase/protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P50750 O60563
• Total number of polymer chains: 2
• Total formula weight: 73059.87

Authors

Baumli, S.,Hole, A.J.,Endicott, J.A. (deposition date: 2012-03-26, release date: 2012-09-12, Last modification date: 2014-10-22)

• Primary citation: Baumli, S.,Hole, A.J.,Wang, L.Z.,Noble, M.E.,Endicott, J.A.; The CDK9 tail determines the reaction pathway of positive transcription elongation factor b.; Structure, 20:1788-1795, 2012; PubMed: 22959624; DOI: 10.1016/j.str.2012.08.011

Experimental method

X-RAY DIFFRACTION (3.6 Å)