1FS4

Structures of glycogen phosphorylase-inhibitor complexes and the implications for structure-based drug design

Summary for 1FS4

Entry DOI	10.2210/pdb1fs4/pdb
Related	1B4D 1FTQ 1FTW 1FTY 1FU4 1FU7 1FU8 1GGN
Descriptor	GLYCOGEN PHOSPHORYLASE, 1-DEOXY-1-METHOXYCARBAMIDO-BETA-D-GLUCO-2-HEPTULOPYRANOSONAMIDE, PYRIDOXAL-5'-PHOSPHATE, ... (4 entities in total)
Functional Keywords	enzyme-inhibitor complex, transferase
Biological source	Oryctolagus cuniculus (rabbit)
Total number of polymer chains	1
Total formula weight	97818.58
Authors	Watson, K.A.,Tsitsanou, K.E.,Gregoriou, M.,Zographos, S.E.,Skamnaki, V.T.,Oikonomakos, N.G.,Fleet, G.W.,Johnson, L.N. (deposition date: 2000-09-08, release date: 2000-10-04, Last modification date: 2020-07-29)
Primary citation	Watson, K.A.,Chrysina, E.D.,Tsitsanou, K.E.,Zographos, S.E.,Archontis, G.,Fleet, G.W.,Oikonomakos, N.G. Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase. Proteins, 61:966-983, 2005 Cited by PubMed: 16222658 DOI: 10.1002/prot.20653 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.38 Å)

Structure validation