1FTY
STRUCTURES OF GLYCOGEN PHOSPHORYLASE-INHIBITOR COMPLEXES AND THE IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN
Summary for 1FTY
Entry DOI | 10.2210/pdb1fty/pdb |
Related | 1B4D 1FS4 1FTQ 1FTW 1FU4 1FU7 1FU8 1GGN |
Descriptor | GLYCOGEN PHOSPHORYLASE, 8,9,10-TRIHYDROXY-7-HYDROXYMETHYL-3-METHYL-6-OXA-1,3-DIAZA-SPIRO[4.5]DECANE-2,4-DIONE, PYRIDOXAL-5'-PHOSPHATE, ... (4 entities in total) |
Functional Keywords | transferase, glycogen phosphorylase, inhibitor complex, catalytic site, design |
Biological source | Oryctolagus cuniculus (rabbit) |
Total number of polymer chains | 1 |
Total formula weight | 97800.56 |
Authors | Watson, K.A.,Tsitsanou, K.E.,Gregoriou, M.,Zographos, S.E.,Skamnaki, V.T.,Oikonomakos, N.G.,Fleet, G.W.,Johnson, L.N. (deposition date: 2000-09-13, release date: 2000-10-04, Last modification date: 2023-08-09) |
Primary citation | Watson, K.A.,Chrysina, E.D.,Tsitsanou, K.E.,Zographos, S.E.,Archontis, G.,Fleet, G.W.,Oikonomakos, N.G. Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase. Proteins, 61:966-983, 2005 Cited by PubMed: 16222658DOI: 10.1002/prot.20653 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.38 Å) |
Structure validation
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