3K44
| Crystal Structure of Drosophila melanogaster Pur-alpha | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Purine-rich binding protein-alpha, ... | Authors: | Graebsch, A, Roche, S, Niessing, D. | Deposit date: | 2009-10-05 | Release date: | 2009-10-27 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | X-ray structure of Pur-alpha reveals a Whirly-like fold and an unusual nucleic-acid binding surface Proc.Natl.Acad.Sci.USA, 106, 2009
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1QQP
| FOOT-AND-MOUTH DISEASE VIRUS/ OLIGOSACCHARIDE RECEPTOR COMPLEX. | Descriptor: | 2-O-sulfo-alpha-L-gulopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-gulopyranuronic acid, PROTEIN (GENOME POLYPROTEIN) | Authors: | Fry, E.E, Lea, S.M, Jackson, T, Newman, J.W.I, Ellard, F.M, Blakemore, W.E, Abu-Ghazaleh, R, Samuel, A, King, A.M.Q, Stuart, D.I. | Deposit date: | 1999-05-20 | Release date: | 1999-06-18 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structure and function of a foot-and-mouth disease virus-oligosaccharide receptor complex. EMBO J., 18, 1999
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3K8O
| Crystal structure of human purine nucleoside phosphorylase in complex with DATMe-ImmH | Descriptor: | 7-({[(1R,2S)-2,3-DIHYDROXY-1-(HYDROXYMETHYL)PROPYL]AMINO}METHYL)-3,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE, Purine nucleoside phosphorylase, SULFATE ION | Authors: | Ho, M, Rinaldo-matthis, A, Almo, S.C, Schramm, V.L. | Deposit date: | 2009-10-14 | Release date: | 2010-03-02 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of human purine nucleoside phosphorylase in complex with DATMe-Immucillin H Proc.Natl.Acad.Sci.USA, 2010
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3KAJ
| Apoenzyme structure of homoglutathione synthetase from Glycine max in open conformation | Descriptor: | Homoglutathione synthetase | Authors: | Galant, A, Arkus, K.A.J, Zubieta, C, Cahoon, R.E, Jez, J.M. | Deposit date: | 2009-10-19 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for Evolution of Product Diversity in Soybean Glutathione Biosynthesis. Plant Cell, 21, 2009
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5J4H
| Structure of humanised RadA-mutant humRadA22F in complex with indole-6-carboxylic acid | Descriptor: | 1H-indole-6-carboxylic acid, CALCIUM ION, DIMETHYL SULFOXIDE, ... | Authors: | Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M. | Deposit date: | 2016-04-01 | Release date: | 2016-10-19 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.374 Å) | Cite: | Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016
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3J8J
| Tilted state of actin, T1 | Descriptor: | Actin, alpha skeletal muscle | Authors: | Galkin, V.E, Orlova, A, Vos, M.R, Schroder, G.F, Egelman, E.H. | Deposit date: | 2014-11-07 | Release date: | 2015-01-14 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (12 Å) | Cite: | Near-atomic resolution for one state of f-actin. Structure, 23, 2015
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3J2C
| Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM | Descriptor: | 16S rRNA body domain, 16S rRNA head domain | Authors: | Guo, Q, Goto, S, Chen, Y, Muto, A, Himeno, H, Deng, H, Lei, J, Gao, N. | Deposit date: | 2012-09-28 | Release date: | 2013-01-16 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (13.2 Å) | Cite: | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process Nucleic Acids Res., 41, 2013
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3J92
| Structure and assembly pathway of the ribosome quality control complex | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Shao, S, Brown, A, Santhanam, B, Hegde, R.S. | Deposit date: | 2014-12-02 | Release date: | 2015-01-21 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure and Assembly Pathway of the Ribosome Quality Control Complex. Mol.Cell, 57, 2015
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3K9U
| Crystal structure of paia acetyltransferase (ta0374) from thermoplasma acidophilum | Descriptor: | ACETYL COENZYME *A, BROMIDE ION, CHLORIDE ION, ... | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-10-16 | Release date: | 2009-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the novel PaiA N-acetyltransferase from Thermoplasma acidophilum involved in the negative control of sporulation and degradative enzyme production. Proteins, 79, 2011
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3JAG
| Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | Authors: | Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V. | Deposit date: | 2015-06-10 | Release date: | 2015-08-12 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.65 Å) | Cite: | Structural basis for stop codon recognition in eukaryotes. Nature, 524, 2015
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3J29
| Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM | Descriptor: | 16S rRNA | Authors: | Guo, Q, Goto, S, Chen, Y, Muto, A, Himeno, H, Deng, H, Lei, J, Gao, N. | Deposit date: | 2012-09-28 | Release date: | 2013-01-16 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (14 Å) | Cite: | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process Nucleic Acids Res., 41, 2013
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3JRK
| A putative tagatose 1,6-diphosphate aldolase from Streptococcus pyogenes | Descriptor: | GLYCEROL, Tagatose 1,6-diphosphate aldolase 2 | Authors: | Fan, Y, Volkart, L, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-09-08 | Release date: | 2009-09-22 | Last modified: | 2017-11-01 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | The crystal structure of a putative tagatose 1,6-diphosphate aldolase from Streptococcus pyogenes To be Published
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5JBT
| Mesotrypsin in complex with cleaved amyloid precursor like protein 2 inhibitor (APLP2) | Descriptor: | Amyloid-like protein 2, CALCIUM ION, PRSS3 protein, ... | Authors: | Kayode, O, Wang, R, Pendlebury, D, Soares, A, Radisky, E.S. | Deposit date: | 2016-04-13 | Release date: | 2016-11-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | An Acrobatic Substrate Metamorphosis Reveals a Requirement for Substrate Conformational Dynamics in Trypsin Proteolysis. J. Biol. Chem., 291, 2016
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3J2F
| Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM | Descriptor: | 16S rRNA | Authors: | Guo, Q, Goto, S, Chen, Y, Muto, A, Himeno, H, Deng, H, Lei, J, Gao, N. | Deposit date: | 2012-09-28 | Release date: | 2013-01-16 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (17.6 Å) | Cite: | Dissecting the in vivo assembly of the 30S ribosomal subunit reveals the role of RimM and general features of the assembly process. Nucleic Acids Res., 41, 2013
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3JW4
| The structure of a putative MarR family transcriptional regulator from Clostridium acetobutylicum | Descriptor: | GLYCEROL, IMIDAZOLE, POTASSIUM ION, ... | Authors: | Cuff, M.E, Bigelow, L, Moy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-09-17 | Release date: | 2009-12-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of a putative MarR family transcriptional regulator from Clostridium acetobutylicum TO BE PUBLISHED
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3JWE
| Crystal structure of human mono-glyceride lipase in complex with SAR629 | Descriptor: | 1-[bis(4-fluorophenyl)methyl]-4-(1H-1,2,4-triazol-1-ylcarbonyl)piperazine, MGLL protein | Authors: | Bertrand, T, Auge, F, Houtmann, J, Rak, A, Vallee, F, Mikol, V, Berne, P.F, Michot, N, Cheuret, D, Hoornaert, C, Mathieu, M. | Deposit date: | 2009-09-18 | Release date: | 2010-01-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for human monoglyceride lipase inhibition. J.Mol.Biol., 396, 2010
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3J45
| Structure of a non-translocating SecY protein channel with the 70S ribosome | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L23, 50S ribosomal protein L24, ... | Authors: | Menetret, J.F, Park, E, Gumbart, J.C, Ludtke, S.J, Li, W, Whynot, A, Rapoport, T.A, Akey, C.W. | Deposit date: | 2013-06-18 | Release date: | 2013-10-23 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Structure of the SecY channel during initiation of protein translocation. Nature, 506, 2013
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3J79
| Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, large subunit | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W. | Deposit date: | 2014-06-02 | Release date: | 2014-07-16 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. Elife, 3, 2014
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1QK4
| TOXOPLASMA GONDII HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE IMP COMPLEX | Descriptor: | HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, INOSINIC ACID | Authors: | Heroux, A, White, E.L, Ross, L.J, Borhani, D.W. | Deposit date: | 1999-07-09 | Release date: | 1999-10-17 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal Structures of the Toxoplasma Gondii Hypoxanthine-Guanine Phosphoribosyltransferase Gmp and -Imp Complexes: Comparison of Purine Binding Interactions with the Xmp Complex Biochemistry, 38, 1999
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5JED
| Apo-structure of humanised RadA-mutant humRadA28 | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... | Authors: | Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M. | Deposit date: | 2016-04-18 | Release date: | 2016-10-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.332 Å) | Cite: | Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016
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1Q71
| The structure of microcin J25 is a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone | Descriptor: | microcin J25 | Authors: | Rosengren, K.J, Clark, R, Daly, N.L, Goransson, U, Jones, A, Craik, D.J. | Deposit date: | 2003-08-14 | Release date: | 2003-12-16 | Last modified: | 2012-12-12 | Method: | SOLUTION NMR | Cite: | Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone. J.Am.Chem.Soc., 125, 2003
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1QLR
| CRYSTAL STRUCTURE OF THE FAB FRAGMENT OF A HUMAN MONOCLONAL IgM COLD AGGLUTININ | Descriptor: | IGM FAB REGION IV-J(H4)-C (KAU COLD AGGLUTININ), IGM KAPPA CHAIN V-III (KAU COLD AGGLUTININ), alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Carvalho, J.G, Cauerhff, A, Goldbaum, F, Leoni, J, Polikarpov, I. | Deposit date: | 1999-09-11 | Release date: | 2000-09-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Three-dimensional structure of the Fab from a human IgM cold agglutinin. J Immunol., 165, 2000
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8PF2
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7OAJ
| Crystal structure of pseudokinase CASK in complex with compound 7 | Descriptor: | 1,2-ETHANEDIOL, 4-(cyclopentylamino)-2-[(3,4-dichlorophenyl)methylamino]-N-[3-(2-oxidanylidenepyrrolidin-1-yl)propyl]pyrimidine-5-carboxamide, Peripheral plasma membrane protein CASK | Authors: | Chaikuad, A, Russ, N, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2021-04-19 | Release date: | 2021-05-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Design and Development of a Chemical Probe for Pseudokinase Ca 2+ /calmodulin-Dependent Ser/Thr Kinase. J.Med.Chem., 64, 2021
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7OAI
| Crystal structure of pseudokinase CASK in complex with PFE-PKIS12 | Descriptor: | 1,2-ETHANEDIOL, 4-(Cyclopentylamino)-2-[(2,5-dichlorophenyl)methylamino]-N-[3-(2-oxo-1,3-oxazolidin-3-yl)propyl]pyrimidine-5-carboxamide, Peripheral plasma membrane protein CASK | Authors: | Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2021-04-19 | Release date: | 2021-05-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Design and Development of a Chemical Probe for Pseudokinase Ca 2+ /calmodulin-Dependent Ser/Thr Kinase. J.Med.Chem., 64, 2021
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