6RS2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6rs2 by Molmil](/molmil-images/mine/6rs2) | Structure of the Bateman module of human CNNM4. | Descriptor: | Metal transporter CNNM4 | Authors: | Corral-Rodriguez, M.A, Stuiver, M, Gomez-Garcia, I, Oyenarte, I, Gimenez, P, Ereno-Orbea, J, Diercks, T, Muller, D, Martinez-Cruz, L.A. | Deposit date: | 2019-05-21 | Release date: | 2020-07-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.694 Å) | Cite: | Structural Insights into the Intracellular Region of the Human Magnesium Transport Mediator CNNM4. Int J Mol Sci, 20, 2019
|
|
6G52
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6g52 by Molmil](/molmil-images/mine/6g52) | CRYSTAL STRUCTURE OF THE CNMP BINDING DOMAIN OF THE MAGNESIUM TRANSPORTER CNNM4 | Descriptor: | Metal transporter CNNM4 | Authors: | Gimenez, P, Oyenarte, I, Hardy, S, Zubillaga, M, Merino, N, Blanco, F.J, Siliqi, D, Tremblay, M, Muller, D, Martinez-Cruz, L.A. | Deposit date: | 2018-03-28 | Release date: | 2019-04-10 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (3.691 Å) | Cite: | Structural Insights into the Intracellular Region of the Human Magnesium Transport Mediator CNNM4. Int J Mol Sci, 20, 2019
|
|
6P6F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6p6f by Molmil](/molmil-images/mine/6p6f) | BG505 SOSIP-I53-50NP | Descriptor: | I53-50A.1NT1, I53-50B.4PT1 | Authors: | Berndsen, Z.T, Ward, A.B. | Deposit date: | 2019-06-03 | Release date: | 2019-06-19 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle. Nat Commun, 10, 2019
|
|
7C3G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7c3g by Molmil](/molmil-images/mine/7c3g) | Crystal structure of human ALK2 kinase domain with R206H mutation in complex with a bicyclic pyrazole inhibitor RK-73134 | Descriptor: | 1,2-ETHANEDIOL, Activin receptor type-1, SULFATE ION, ... | Authors: | Sakai, N, Mishima-Tsumagari, C, Matsumoto, T, Shirouzu, M. | Deposit date: | 2020-05-12 | Release date: | 2021-03-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | Novel bicyclic pyrazoles as potent ALK2 (R206H) inhibitors for the treatment of fibrodysplasia ossificans progressiva. Bioorg.Med.Chem.Lett., 38, 2021
|
|
6O3G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o3g by Molmil](/molmil-images/mine/6o3g) | |
6O3K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o3k by Molmil](/molmil-images/mine/6o3k) | |
6O3D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o3d by Molmil](/molmil-images/mine/6o3d) | |
6O3J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o3j by Molmil](/molmil-images/mine/6o3j) | Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41) and phosphatidic acid (06:0 PA) | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, (4S)-2-METHYL-2,4-PENTANEDIOL, MPER peptide, ... | Authors: | Irimia, A, Wilson, I.A. | Deposit date: | 2019-02-26 | Release date: | 2019-12-04 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.416 Å) | Cite: | An MPER antibody neutralizes HIV-1 using germline features shared among donors. Nat Commun, 10, 2019
|
|
6O3L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o3l by Molmil](/molmil-images/mine/6o3l) | |
6O41
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o41 by Molmil](/molmil-images/mine/6o41) | |
6O42
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o42 by Molmil](/molmil-images/mine/6o42) | |
2E29
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2e29 by Molmil](/molmil-images/mine/2e29) | Solution structure of the GUCT domain from human ATP-dependent RNA helicase DDX50, DEAD box protein 50 | Descriptor: | ATP-dependent RNA helicase DDX50 | Authors: | Ohnishi, S, Paakkonen, K, Guntert, P, Sato, M, Koshiba, S, Harada, T, Watanabe, S, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-11-10 | Release date: | 2007-05-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the GUCT domain from human RNA helicase II/Gubeta reveals the RRM fold, but implausible RNA interactions Proteins, 74, 2008
|
|
6O3U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6o3u by Molmil](/molmil-images/mine/6o3u) | |
2D8B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2d8b by Molmil](/molmil-images/mine/2d8b) | Solution structure of the second tandem cofilin-domain of mouse twinfilin | Descriptor: | Twinfilin-1 | Authors: | Goroncy, A.K, Kigawa, T, Koshiba, S, Sato, M, Kobayashi, N, Tochio, N, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-12-02 | Release date: | 2006-06-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR solution structures of actin depolymerizing factor homology domains Protein Sci., 18, 2009
|
|
2DWV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2dwv by Molmil](/molmil-images/mine/2dwv) | Solution structure of the second WW domain from mouse salvador homolog 1 protein (mWW45) | Descriptor: | Salvador homolog 1 protein | Authors: | Ohnishi, S, Kigawa, T, Koshiba, S, Tomizawa, T, Sato, M, Tochio, N, Inoue, M, Harada, T, Watanabe, S, Guntert, P, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-08-17 | Release date: | 2007-02-17 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of an atypical WW domain in a novel beta-clam-like dimeric form Febs Lett., 581, 2007
|
|
2DWG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2dwg by Molmil](/molmil-images/mine/2dwg) | RUN domain of Rap2 interacting protein x, crystallized in P2(1)2(1)2(1) space group | Descriptor: | Protein RUFY3 | Authors: | Kukimoto-Niino, M, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-08-11 | Release date: | 2006-10-24 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.22 Å) | Cite: | Crystal Structure of the RUN Domain of the RAP2-interacting Protein x J.Biol.Chem., 281, 2006
|
|
6JUX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jux by Molmil](/molmil-images/mine/6jux) | Crystal structure of human ALK2 kinase domain with R206H mutation in complex with RK-71807 | Descriptor: | 4-(1-ethyl-3-pyridin-3-yl-pyrazol-4-yl)-~{N}-(4-piperazin-1-ylphenyl)pyrimidin-2-amine, Activin receptor type-1, SULFATE ION | Authors: | Sakai, N, Mishima-Tsumagari, C, Matsumoto, T, Shirouzu, M. | Deposit date: | 2019-04-15 | Release date: | 2020-04-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural Basis of Activin Receptor-Like Kinase 2 (R206H) Inhibition by Bis-heteroaryl Pyrazole-Based Inhibitors for the Treatment of Fibrodysplasia Ossificans Progressiva Identified by the Integration of Ligand-Based and Structure-Based Drug Design Approaches. Acs Omega, 5, 2020
|
|
6NZT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nzt by Molmil](/molmil-images/mine/6nzt) | |
2E63
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2e63 by Molmil](/molmil-images/mine/2e63) | Solution structure of the NEUZ domain in KIAA1787 protein | Descriptor: | KIAA1787 protein | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-12-25 | Release date: | 2007-06-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural and functional characterization of the NHR1 domain of the Drosophila neuralized E3 ligase in the notch signaling pathway. J.Mol.Biol., 393, 2009
|
|
2CXF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cxf by Molmil](/molmil-images/mine/2cxf) | RUN domain of Rap2 interacting protein x, crystallized in C2 space group | Descriptor: | rap2 interacting protein x | Authors: | Kukimoto-Niino, M, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-06-29 | Release date: | 2005-12-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.07 Å) | Cite: | Crystal Structure of the RUN Domain of the RAP2-interacting Protein x J.Biol.Chem., 281, 2006
|
|
2CXL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cxl by Molmil](/molmil-images/mine/2cxl) | RUN domain of Rap2 interacting protein x, crystallized in I422 space group | Descriptor: | rap2 interacting protein x | Authors: | Kukimoto-Niino, M, Umehara, T, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-06-30 | Release date: | 2005-12-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal Structure of the RUN Domain of the RAP2-interacting Protein x J.Biol.Chem., 281, 2006
|
|
3UMX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3umx by Molmil](/molmil-images/mine/3umx) | Crystal structure of Pim1 kinase in complex with inhibitor (Z)-2-[(1H-indol-3-yl)methylene]-7-(azepan-1-ylmethyl)-6-hydroxybenzofuran-3(2H)-one | Descriptor: | (2Z)-7-(azepan-1-ylmethyl)-6-hydroxy-2-(1H-indol-3-ylmethylidene)-1-benzofuran-3(2H)-one, Proto-oncogene serine/threonine-protein kinase pim-1, SULFATE ION | Authors: | Parker, L.J, Handa, N, Yokoyama, S. | Deposit date: | 2011-11-15 | Release date: | 2012-08-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Flexibility of the P-loop of Pim-1 kinase: observation of a novel conformation induced by interaction with an inhibitor Acta Crystallogr.,Sect.F, 68, 2012
|
|
3UIX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3uix by Molmil](/molmil-images/mine/3uix) | |
2E5S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2e5s by Molmil](/molmil-images/mine/2e5s) | Solution structure of the zf-CCCHx2 domain of muscleblind-like 2, isoform 1 [Homo sapiens] | Descriptor: | OTTHUMP00000018578, ZINC ION | Authors: | Dang, W, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-12-22 | Release date: | 2007-06-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the RNA binding domain in the human muscleblind-like protein 2 Protein Sci., 18, 2009
|
|
2DWK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2dwk by Molmil](/molmil-images/mine/2dwk) | Crystal structure of the RUN domain of mouse Rap2 interacting protein x | Descriptor: | Protein RUFY3 | Authors: | Kukimoto-Niino, M, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2006-08-15 | Release date: | 2006-08-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of the RUN Domain of the RAP2-interacting Protein x J.Biol.Chem., 281, 2006
|
|