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6XCA
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BU of 6xca by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C105
Descriptor: C105 Heavy Chain, C105 Light Chain, SULFATE ION
Authors:Sharaf, N.G, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-06-08
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Cell, 182, 2020
6XCN
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BU of 6xcn by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-06-08
Release date:2020-07-01
Last modified:2020-09-02
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Cell, 182, 2020
7RYV
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BU of 7ryv by Molmil
Anti-HIV neutralizing antibody Ab1573 Fab isolated from sequentially immunized macaques
Descriptor: Ab1573 Fab heavy chain, Ab1573 Fab light chain
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2021-08-26
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7RYU
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BU of 7ryu by Molmil
Anti-HIV neutralizing antibody Ab1303 Fab isolated from sequentially immunized mcaques
Descriptor: Ab1303 Fab heavy chain, Ab1303 Fab light chain
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2021-08-26
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7TFN
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BU of 7tfn by Molmil
Cryo-EM structure of CD4bs antibody Ab1303 in complex with HIV-1 Env trimer BG505 SOSIP.664
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-HIV-1 CD4bs antibody Fab Ab1303 - Heavy chain, ...
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2022-01-06
Release date:2022-01-19
Last modified:2022-02-23
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
7TFO
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BU of 7tfo by Molmil
Cryo-EM structure of HIV-1 Env trimer BG505 SOSIP.664 in complex with CD4bs antibody Ab1573
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD4 binding site antibody Ab1573 - Fab heavy chain, ...
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2022-01-06
Release date:2022-01-26
Last modified:2022-02-23
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Neutralizing antibodies induced in immunized macaques recognize the CD4-binding site on an occluded-open HIV-1 envelope trimer.
Nat Commun, 13, 2022
5VJ6
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BU of 5vj6 by Molmil
BG505 SOSIP.664 in complex with broadly neutralizing antibodies PG9 and 8ANC195
Descriptor: 8ANC195 Fab heavy chain, 8ANC195 Fab light chain, Envelope glycoprotein gp160, ...
Authors:Wang, H, Bjorkman, P.J.
Deposit date:2017-04-18
Release date:2017-06-21
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies.
Elife, 6, 2017
5VIY
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BU of 5viy by Molmil
BG505 SOSIP.664 in complex with broadly neutralizing antibodies BG1 and 8ANC195
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 Fab heavy chain, ...
Authors:Wang, H, Bjorkman, P.J.
Deposit date:2017-04-17
Release date:2017-06-21
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies.
Elife, 6, 2017
5THR
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BU of 5thr by Molmil
Cryo-EM structure of a BG505 Env-sCD4-17b-8ANC195 complex
Descriptor: 17b Fab VH domain, 17b Fab VL domain, 8ANC195 G52K5 VH domain, ...
Authors:Wang, H, Bjorkman, P.J.
Deposit date:2016-09-30
Release date:2016-11-16
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:Cryo-EM structure of a CD4-bound open HIV-1 envelope trimer reveals structural rearrangements of the gp120 V1V2 loop.
Proc.Natl.Acad.Sci.USA, 113, 2016
5UD9
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BU of 5ud9 by Molmil
Crystal structure of 354BG18 Fab
Descriptor: Fab heavy chain, Light chain
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2016-12-23
Release date:2017-02-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller.
Sci Transl Med, 9, 2017
7UGN
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BU of 7ugn by Molmil
Cryo-EM structure of BG24 inferred germline Fabs with germline CDR3s and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 - Class 1
Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dam, K.A, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-10-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGO
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BU of 7ugo by Molmil
Cryo-EM structure of BG24 inferred germline Fabs with mature CDR3s and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1
Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dam, K.A, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-10-26
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGM
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BU of 7ugm by Molmil
Crystal Structure of BG24-iGL CDR3mat Fab
Descriptor: BG24-iGL CDR3mat Fab heavy chain, BG24-iGL CDR3mat Fab light chain
Authors:Dam, K.A, Barnes, C.O, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGQ
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BU of 7ugq by Molmil
Cryo-EM structure of BG24 Fabs with an inferred germline CDRL1 and 10-1074 Fabs in complex with HIV-1 Env 6405-SOSIP.664
Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dam, K.A, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-11-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
7UGP
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BU of 7ugp by Molmil
Cryo-EM structure of BG24 Fabs with an inferred germline light chain and 10-1074 Fabs in complex with HIV-1 Env immunogen BG505-SOSIPv4.1-GT1 containing the N276 gp120 glycan- Class 1
Descriptor: 10-1074 Fab heavy chain, 10-1074 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Dam, K.A, Bjorkman, P.J.
Deposit date:2022-03-25
Release date:2022-11-09
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:HIV-1 CD4-binding site germline antibody-Env structures inform vaccine design.
Nat Commun, 13, 2022
6U0N
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BU of 6u0n by Molmil
Asymmetrically open conformational state (Class II) of HIV-1 Env trimer BG505 SOSIP.664 in complex with sCD4 and E51 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E51 Fab heavy chain, ...
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2019-08-14
Release date:2019-12-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody.
Nat.Struct.Mol.Biol., 26, 2019
6U0L
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BU of 6u0l by Molmil
Asymmetrically open conformational state (Class I) of HIV-1 Env trimer BG505 SOSIP.664 in complex with sCD4 and E51 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, E51 Fab heavy chain, ...
Authors:Yang, Z, Bjorkman, P.J.
Deposit date:2019-08-14
Release date:2019-12-11
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Asymmetric opening of HIV-1 Env bound to CD4 and a coreceptor-mimicking antibody.
Nat.Struct.Mol.Biol., 26, 2019
7K8T
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BU of 7k8t by Molmil
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, C002 (State 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C002 Fab Heavy Chain, ...
Authors:Malyutin, A.G, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8N
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BU of 7k8n by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C102
Descriptor: C102 Fab Heavy Chain, C102 Fab Light Chain, DI(HYDROXYETHYL)ETHER, ...
Authors:Jette, C.A, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8X
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BU of 7k8x by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C121 Fab Heavy chain, C121 Fab Light chain, ...
Authors:Abernathy, M.E, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8Q
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BU of 7k8q by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C121
Descriptor: C121 Fab Heavy Chain, C121 Fab Light Chain, GLYCEROL
Authors:Abernathy, M.E, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8Y
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BU of 7k8y by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C121 (State 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, C121 Fab Heavy chain, C121 Fab Light chain, ...
Authors:Abernathy, M.E, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8P
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BU of 7k8p by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C110
Descriptor: C110 Fab Heavy Chain, C110 Fab Light Chain
Authors:Dam, K.A, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8S
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BU of 7k8s by Molmil
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, C002 (state 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C002 Fab Heavy Chain, ...
Authors:Barnes, C.O, Malyutin, A.G, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2021-01-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020
7K8R
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BU of 7k8r by Molmil
Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C135
Descriptor: C135 Fab Heavy Chain, C135 Fab Light Chain, GLYCEROL
Authors:Jette, C.A, Barnes, C.O, Bjorkman, P.J.
Deposit date:2020-09-27
Release date:2020-10-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Nature, 588, 2020

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