7K8R

Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C135

Summary for 7K8R

• Entry DOI: 10.2210/pdb7k8r/pdb
• Descriptor: C135 Fab Heavy Chain, C135 Fab Light Chain, GLYCEROL, ... (4 entities in total)
• Functional Keywords: human neutralizing antibody, sars-cov-2, receptor binding domain, covid-19, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 47488.83

Authors

Jette, C.A.,Barnes, C.O.,Bjorkman, P.J. (deposition date: 2020-09-27, release date: 2020-10-21, Last modification date: 2023-10-18)

• Primary citation: Barnes, C.O.,Jette, C.A.,Abernathy, M.E.,Dam, K.A.,Esswein, S.R.,Gristick, H.B.,Malyutin, A.G.,Sharaf, N.G.,Huey-Tubman, K.E.,Lee, Y.E.,Robbiani, D.F.,Nussenzweig, M.C.,West Jr., A.P.,Bjorkman, P.J.; SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.; Nature, 588:682-687, 2020; PubMed: 33045718; DOI: 10.1038/s41586-020-2852-1

Experimental method

X-RAY DIFFRACTION (2 Å)