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7WP6
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BU of 7wp6 by Molmil
Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK in complex with three neutralizing antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 36H6 heavy chain, ...
Authors:Zheng, Q, Sun, H, Yuan, Q, Li, S, Xia, N.
Deposit date:2022-01-23
Release date:2023-03-01
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.81 Å)
Cite:Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine.
Cell Host Microbe, 30, 2022
7WP8
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BU of 7wp8 by Molmil
Cryo-EM structure of SARS-CoV-2 recombinant spike protein STFK1628x in complex with three neutralizing antibodies
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 heavy chain, ...
Authors:Zheng, Q, Sun, H, Yuan, Q, Li, S, Xia, N.
Deposit date:2022-01-23
Release date:2023-03-08
Last modified:2023-09-13
Method:ELECTRON MICROSCOPY (3.88 Å)
Cite:Lineage-mosaic and mutation-patched spike proteins for broad-spectrum COVID-19 vaccine.
Cell Host Microbe, 30, 2022
6NPJ
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BU of 6npj by Molmil
Structure of the NKCC1 CTD
Descriptor: Sodium-potassium-chloride cotransporter 1
Authors:Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
Deposit date:2019-01-17
Release date:2019-07-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
6WW9
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BU of 6ww9 by Molmil
Crystal structure of human REV7(R124A)-SHLD3(35-58) complex
Descriptor: Mitotic spindle assembly checkpoint protein MAD2B, Shieldin complex subunit 3
Authors:Xie, W, Patel, D.J.
Deposit date:2020-05-08
Release date:2021-03-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular mechanisms of assembly and TRIP13-mediated remodeling of the human Shieldin complex.
Proc.Natl.Acad.Sci.USA, 118, 2021
7LUS
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BU of 7lus by Molmil
IgG2 Fc Charge Pair Mutation version 1 (CPMv1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin heavy constant gamma 2
Authors:Sudom, A, Whittington, D, Garces, F, Wang, Z.
Deposit date:2021-02-23
Release date:2021-09-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Next generation Fc scaffold for multispecific antibodies.
Iscience, 24, 2021
7LUR
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BU of 7lur by Molmil
Stable Effector Functionless 2 (SEFL2) IgG1 Fc Scaffold Bound to a Minimized Version of the B-domain (Mini-Z) from Protein A Called Z34C
Descriptor: Immunoglobulin heavy constant gamma 1, Mini Z domain
Authors:Sudom, A, Garces, F, Wang, Z.
Deposit date:2021-02-23
Release date:2021-09-15
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Next generation Fc scaffold for multispecific antibodies.
Iscience, 24, 2021
3PL9
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BU of 3pl9 by Molmil
Crystal structure of spinach minor light-harvesting complex CP29 at 2.80 angstrom resolution
Descriptor: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ...
Authors:Pan, X.W, Li, M, Wan, T, Wang, L.F, Jia, C.J, Hou, Z.Q, Zhao, X.L, Zhang, J.P, Chang, W.R.
Deposit date:2010-11-14
Release date:2011-02-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into energy regulation of light-harvesting complex CP29 from spinach.
Nat.Struct.Mol.Biol., 18, 2011
8FTI
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BU of 8fti by Molmil
Cryo-EM structure of the Cas13bt3-crRNA-target RNA ternary complex in activated state
Descriptor: Integrase, crRNA-linker-target hairpin RNA
Authors:Gao, Y, Deng, X.
Deposit date:2023-01-12
Release date:2023-09-27
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for the activation of a compact CRISPR-Cas13 nuclease.
Nat Commun, 14, 2023
7U87
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BU of 7u87 by Molmil
Product of 13mer primer with activated G monomer diastereomer 1
Descriptor: 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LCC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*(G46)P*(G46))-3')
Authors:Fang, Z, Szostak, J.W.
Deposit date:2022-03-08
Release date:2023-03-15
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension.
J.Am.Chem.Soc., 2024
7U88
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BU of 7u88 by Molmil
Product of 13mer primer with activated G monomer diastereomer 2
Descriptor: 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*(G46)P*(G46))-3'), SULFATE ION
Authors:Fang, Z, Szostak, J.W.
Deposit date:2022-03-08
Release date:2023-03-15
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension.
J.Am.Chem.Soc., 2024
7U89
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BU of 7u89 by Molmil
Product of 14mer primer with activated G monomer diastereomer 1
Descriptor: 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*(G46))-3')
Authors:Fang, Z, Szostak, J.W.
Deposit date:2022-03-08
Release date:2023-03-15
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension.
J.Am.Chem.Soc., 2024
7U8A
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BU of 7u8a by Molmil
Product of 14mer primer with activated G monomer diastereomer 2
Descriptor: 5'-O-[(R)-(2-amino-1H-imidazol-1-yl)(sulfanyl)phosphoryl]guanosine, MAGNESIUM ION, RNA (5'-R(*(LKC)P*(LCC)P*(LCC)P*(LCG)P*AP*CP*UP*UP*AP*AP*GP*UP*CP*GP*(G46))-3')
Authors:Fang, Z, Szostak, J.W.
Deposit date:2022-03-08
Release date:2023-03-15
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension.
J.Am.Chem.Soc., 2024
6KEY
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BU of 6key by Molmil
Structural basis for the regulation of inducible nitric oxide synthase (iNOS) by the SPRY domain-containing SOCS box protein 2 (SPSB2)
Descriptor: Nitric oxide synthase, inducible, SPRY domain-containing SOCS box protein 2
Authors:Li, K, Kuang, Z.
Deposit date:2019-07-05
Release date:2020-07-01
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Structural basis for the regulation of inducible nitric oxide synthase by the SPRY domain-containing SOCS box protein SPSB2, an E3 ubiquitin ligase.
Nitric Oxide, 113-114, 2021
6X7V
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BU of 6x7v by Molmil
Crystal Structure of the Human Nudix Hydrolase Nudt16
Descriptor: CHLORIDE ION, MANGANESE (II) ION, U8 snoRNA-decapping enzyme
Authors:Hamilton, K, Tong, L.
Deposit date:2020-05-30
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mammalian Nudix proteins cleave nucleotide metabolite caps on RNAs.
Nucleic Acids Res., 48, 2020
6NPL
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BU of 6npl by Molmil
Cryo-EM structure of NKCC1
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ...
Authors:Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
Deposit date:2019-01-17
Release date:2019-07-31
Last modified:2019-08-28
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
7PB8
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BU of 7pb8 by Molmil
Crystal structure of the CENP-OPQUR complex
Descriptor: Centromere protein O, Centromere protein P, Centromere protein Q, ...
Authors:Bellini, D, Yatskevich, S, Muir, K.W, Barford, D.
Deposit date:2021-07-31
Release date:2022-04-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.68 Å)
Cite:Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
7PB4
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BU of 7pb4 by Molmil
Cenp-HIK 3-protein complex
Descriptor: Centromere protein H, Centromere protein I, Centromere protein K
Authors:Bellini, D, Yatskevich, S, Muir, W.K, Barford, D.
Deposit date:2021-07-30
Release date:2022-04-27
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
6NPH
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BU of 6nph by Molmil
Structure of NKCC1 TM domain
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ...
Authors:Feng, L, Liao, M.F, Orlando, B, Zhang, J.R.
Deposit date:2019-01-17
Release date:2019-07-31
Last modified:2020-01-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure and mechanism of the cation-chloride cotransporter NKCC1.
Nature, 572, 2019
8WMI
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BU of 8wmi by Molmil
Cryo-EM structure of DiCas7-11 mutant in complex with crRNA
Descriptor: CRISPR-associated RAMP family protein, ZINC ION, crRNA (39-MER)
Authors:Ma, H.Y, Tang, X.D.
Deposit date:2023-10-03
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.
Signal Transduct Target Ther, 9, 2024
4WY4
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BU of 4wy4 by Molmil
Crystal structure of autophagic SNARE complex
Descriptor: Synaptosomal-associated protein 29, Syntaxin-17, Vesicle-associated membrane protein 8
Authors:Zhao, M, Brunger, A.T.
Deposit date:2014-11-15
Release date:2015-02-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes.
Nature, 520, 2015
6X7U
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BU of 6x7u by Molmil
Crystal Structure of the Human Nudix Hydrolase Nudt16 in complex with FAD
Descriptor: ADENOSINE MONOPHOSPHATE, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ...
Authors:Hamilton, K, Tong, L.
Deposit date:2020-05-30
Release date:2020-07-01
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mammalian Nudix proteins cleave nucleotide metabolite caps on RNAs.
Nucleic Acids Res., 48, 2020
8W2O
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BU of 8w2o by Molmil
Yeast U1 snRNP with humanized U1C Zinc-Finger domain
Descriptor: 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA, Pre-mRNA-processing factor 39, ...
Authors:Shi, S.S, Kuang, Z.L, Zhao, R.
Deposit date:2024-02-20
Release date:2024-05-15
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Selected humanization of yeast U1 snRNP leads to global suppression of pre-mRNA splicing and mitochondrial dysfunction in the budding yeast.
Rna, 30, 2024
8WM4
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BU of 8wm4 by Molmil
Cryo-EM structure of DiCas7-11 in complex with crRNA
Descriptor: CRISPR-associated RAMP family protein, ZINC ION, crRNA (38-MER)
Authors:Ma, H.Y, Tang, X.D.
Deposit date:2023-10-02
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (2.93 Å)
Cite:Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.
Signal Transduct Target Ther, 9, 2024
8WML
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BU of 8wml by Molmil
Cryo-EM structure of Cas7-11-crRNA bound to N-terminal of TPR-CHAT
Descriptor: CHAT domain-containing protein, CRISPR-associated RAMP family protein, ZINC ION, ...
Authors:Ma, H.Y, Tang, X.D.
Deposit date:2023-10-03
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.
Signal Transduct Target Ther, 9, 2024
8WMC
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BU of 8wmc by Molmil
Cryo-EM structure of DiCas7-11-crRNA in complex with regulator
Descriptor: CHAT domain-containing protein, CRISPR-associated RAMP family protein, RNA (38-MER), ...
Authors:Ma, H.Y, Tang, X.D.
Deposit date:2023-10-03
Release date:2024-05-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of negative regulation of CRISPR-Cas7-11 by TPR-CHAT.
Signal Transduct Target Ther, 9, 2024

223532

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