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1N66
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Structure of the pyrimidine-rich internal loop in the Y-domain of poliovirus 3'UTR
分子名称: internal loop in the Y-domain of poliovirus 3'UTR
著者Lescrinier, E.M, Tessari, M, van Kuppeveld, F.J, Melchers, W.J, Hilbers, C.W, Heus, H.A.
登録日2002-11-08
公開日2003-08-19
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the Pyrimidine-rich Internal Loop in the Poliovirus 3'-UTR: The Importance of Maintaining Pseudo-2-fold Symmetry in RNA Helices Containing Two Adjacent Non-canonical Base-pairs.
J.Mol.Biol., 331, 2003
7AKD
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Structure of the SARS-CoV-2 spike glycoprotein in complex with the 47D11 neutralizing antibody Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 47D11 neutralizing antibody heavy chain, ...
著者Fedry, J, Hurdiss, D.L, Wang, C, Li, W, Obal, G, Drulyte, I, Howes, S.C, van Kuppeveld, F.J.M, Foerster, F, Bosch, B.J.
登録日2020-09-30
公開日2021-05-19
最終更新日2021-06-16
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11.
Sci Adv, 7, 2021
7AKJ
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BU of 7akj by Molmil
Structure of the SARS-CoV spike glycoprotein in complex with the 47D11 neutralizing antibody Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Fedry, J, Hurdiss, D.L, Wang, C, Li, W, Obal, G, Drulyte, I, Howes, S.C, van Kuppeveld, F.J.M, Foerster, F, Bosch, B.J.
登録日2020-10-01
公開日2021-05-19
最終更新日2021-06-16
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11.
Sci Adv, 7, 2021
2GV4
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BU of 2gv4 by Molmil
Solution structure of the poliovirus 3'-UTR Y-stem
分子名称: Short RNA strand 5'-GGACCUCUCGAAAGAGUGGUCC-3'
著者Heus, H.A, Zoll, J, Tessari, M, van Kuppeveld, F.J.M, Melchers, W.J.G.
登録日2006-05-02
公開日2007-03-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Breaking pseudo-twofold symmetry in the poliovirus 3'-UTR Y-stem by restoring Watson-Crick base pairs.
Rna, 13, 2007
2GRW
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BU of 2grw by Molmil
Solution structure of the poliovirus 3'-UTR Y-stem
分子名称: 5'-GGACCUCUCGAAAGAGAUGUCC-3'
著者Heus, H.A, Zoll, J, Tessari, M, van Kuppeveld, F.J.M, Melchers, W.J.G.
登録日2006-04-25
公開日2007-03-06
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Breaking pseudo-twofold symmetry in the poliovirus 3'-UTR Y-stem by restoring Watson-Crick base pairs.
Rna, 13, 2007
4Y34
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BU of 4y34 by Molmil
Crystal Structure of Coxsackievirus B3 3D polymerase in complex with GPC-N143
分子名称: 2,2'-[(4-fluorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), 3D polymerase, GLYCEROL, ...
著者Vives-Adrian, L, Ferrer-Orta, C, Cerdaguer, N.
登録日2015-02-10
公開日2015-04-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
4Y3C
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I304V 3D polymerase mutant of EMCV
分子名称: 3D polymerase, CHLORIDE ION, GLYCEROL
著者Verdaguer, N, Ferrer-Orta, C, Vives-Adrian, L.
登録日2015-02-10
公開日2015-04-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
4Y2C
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M300V 3D polymerase mutant of EMCV
分子名称: GLYCEROL, Genome polyprotein
著者Verdaguer, N, Ferrer-Orta, C, Vives-Adrian, L.
登録日2015-02-09
公開日2015-04-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
4Y2A
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BU of 4y2a by Molmil
Crystal Structure of Coxsackie Virus B3 3D polymerase in complex with GPC-N114 inhibitor
分子名称: 2,2'-[(4-chlorobenzene-1,2-diyl)bis(oxy)]bis(5-nitrobenzonitrile), 3D polymerase, GLYCEROL, ...
著者Vives-Adrian, L, Ferrer-Orta, C, Verdaguer, N.
登録日2015-02-09
公開日2015-04-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The RNA Template Channel of the RNA-Dependent RNA Polymerase as a Target for Development of Antiviral Therapy of Multiple Genera within a Virus Family.
Plos Pathog., 11, 2015
5N11
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BU of 5n11 by Molmil
Crystal structure of Human beta1-coronavirus OC43 NL/A/2005 Hemagglutinin-Esterase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ...
著者Bakkers, M.J.G, Feitsma, L.J, de Groot, R.J, Huizinga, E.G.
登録日2017-02-04
公開日2017-03-22
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Betacoronavirus Adaptation to Humans Involved Progressive Loss of Hemagglutinin-Esterase Lectin Activity.
Cell Host Microbe, 21, 2017
8C8P
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BU of 8c8p by Molmil
Structure of the SARS-CoV-2 spike glycoprotein in complex with the 10D12 heavy-chain-only antibody (local refinement)
分子名称: Heavy-chain-only antibody 10D12, Spike glycoprotein,SARS-CoV-2 spike glycoprotein
著者Serna Martin, I, Hurdiss, D.L.
登録日2023-01-20
公開日2023-02-22
最終更新日2023-03-22
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Avidity engineering of human heavy-chain-only antibodies mitigates neutralization resistance of SARS-CoV-2 variants.
Front Immunol, 14, 2023
5CFC
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BU of 5cfc by Molmil
Crystal Structure of Human Cardiovirus SAFV-3
分子名称: VP1, VP2, VP3, ...
著者Mullapudi, E, Plevka, P.
登録日2015-07-08
公開日2016-06-15
最終更新日2018-04-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Genome Release Mechanism of the Human Cardiovirus Saffold Virus 3.
J.Virol., 90, 2016
5CFD
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Crystal Structure of DTT treated Human Cardiovirus SAFV-3
分子名称: VP1, VP2, VP3, ...
著者Mullapudi, E, Plevka, P.
登録日2015-07-08
公開日2016-06-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Genome Release Mechanism of the Human Cardiovirus Saffold Virus 3.
J.Virol., 90, 2016
8R9W
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BU of 8r9w by Molmil
PDCoV spike glycoprotein ectodomain in complex with the 22C10 antibody Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 22C10 antibody heavy chain, ...
著者Debski-Antoniak, O, Hurdiss, D.L.
登録日2023-11-30
公開日2024-06-05
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein.
Nat Commun, 15, 2024
8R9Y
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S1B domain of the PDCoV spike glycoprotein in complex with the 67B12 and 42H3 antibody Fab fragments
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 42H3 antibody heavy chain, ...
著者Debski-Antoniak, O, Hurdiss, D.L.
登録日2023-11-30
公開日2024-06-05
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein.
Nat Commun, 15, 2024
8R9Z
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BU of 8r9z by Molmil
S1B domain of the PDCoV spike glycoprotein in complex with the 67B12 and 46E6 antibody Fab fragments
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 46E6 antibody heavy chain, ...
著者Debski-Antoniak, O, Hurdiss, D.L.
登録日2023-11-30
公開日2024-06-05
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein.
Nat Commun, 15, 2024
8R9X
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BU of 8r9x by Molmil
Local refinement of the PDCoV spike glycoprotein ectodomain in complex with the 22C10 antibody Fab fragment
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Debski-Antoniak, O, Hurdiss, D.L.
登録日2023-11-30
公開日2024-06-05
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein.
Nat Commun, 15, 2024
5JIL
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BU of 5jil by Molmil
Crystal structure of rat coronavirus strain New-Jersey Hemagglutinin-Esterase in complex with 4N-acetyl sialic acid
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-esterase, ...
著者Bakkers, M.J.G, Feitsma, L.J, de Groot, R.J, Huizinga, E.G.
登録日2016-04-22
公開日2016-05-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Coronavirus receptor switch explained from the stereochemistry of protein-carbohydrate interactions and a single mutation.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JIF
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Crystal structure of mouse hepatitis virus strain DVIM Hemagglutinin-Esterase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Zeng, Q.H, Bakkers, M.J.G, Feitsma, L.J, de Groot, R.J, Huizinga, E.G.
登録日2016-04-22
公開日2016-05-11
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Coronavirus receptor switch explained from the stereochemistry of protein-carbohydrate interactions and a single mutation.
Proc.Natl.Acad.Sci.USA, 113, 2016
5BNO
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BU of 5bno by Molmil
Crystal structure of human enterovirus D68 in complex with 6'SLN
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Liu, Y, Sheng, J, Meng, G, Xiao, C, Rossmann, M.G.
登録日2015-05-26
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Sialic acid-dependent cell entry of human enterovirus D68.
Nat Commun, 6, 2015
5BNP
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BU of 5bnp by Molmil
Crystal structure of human enterovirus D68 in complex with 3'SLN
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Liu, Y, Sheng, J, Meng, G, Xiao, C, Rossmann, M.G.
登録日2015-05-26
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Sialic acid-dependent cell entry of human enterovirus D68.
Nat Commun, 6, 2015
5BNN
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Crystal structure of human enterovirus D68 in complex with 6'SL
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Liu, Y, Sheng, J, Meng, G, Xiao, C, Rossmann, M.G.
登録日2015-05-26
公開日2015-11-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Sialic acid-dependent cell entry of human enterovirus D68.
Nat Commun, 6, 2015
4NZ0
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The EMCV 3Dpol structure at 2.8A resolution
分子名称: CHLORIDE ION, GLYCEROL, Genome polyprotein
著者Vives-adrian, L, Ferrer-orta, C, Verdaguer, N.
登録日2013-12-11
公開日2014-03-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The crystal structure of a cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site
J.Virol., 88, 2014
4NYZ
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The EMCV 3Dpol structure with altered motif A conformation at 2.15A resolution
分子名称: GLUTAMINE, GLYCEROL, Genome polyprotein, ...
著者Vives-adrian, L, Lujan, C, Ferrer-orta, C, Verdaguer, N.
登録日2013-12-11
公開日2014-03-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The crystal structure of a cardiovirus RNA-dependent RNA polymerase reveals an unusual conformation of the polymerase active site
J.Virol., 88, 2014
6Y3Y
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Human Coronavirus HKU1 Haemagglutinin-Esterase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin-esterase, ...
著者Hurdiss, D.L, Drulyte, I, Pronker, M.F.
登録日2020-02-19
公開日2020-04-08
最終更新日2020-09-30
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Cryo-EM structure of coronavirus-HKU1 haemagglutinin esterase reveals architectural changes arising from prolonged circulation in humans.
Nat Commun, 11, 2020

 

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