5N11

Crystal structure of Human beta1-coronavirus OC43 NL/A/2005 Hemagglutinin-Esterase

Summary for 5N11

• Entry DOI: 10.2210/pdb5n11/pdb
• Descriptor: Hemagglutinin-esterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: hemagglutin, esterase, hepatitis virus, coronavirus, viral protein, sialic acid
• Biological source: Human coronavirus OC43 (HCoV-OC43)
• Total number of polymer chains: 2
• Total formula weight: 92969.91

Authors

Bakkers, M.J.G.,Feitsma, L.J.,de Groot, R.J.,Huizinga, E.G. (deposition date: 2017-02-04, release date: 2017-03-22, Last modification date: 2024-01-17)

• Primary citation: Bakkers, M.J.,Lang, Y.,Feitsma, L.J.,Hulswit, R.J.,de Poot, S.A.,van Vliet, A.L.,Margine, I.,de Groot-Mijnes, J.D.,van Kuppeveld, F.J.,Langereis, M.A.,Huizinga, E.G.,de Groot, R.J.; Betacoronavirus Adaptation to Humans Involved Progressive Loss of Hemagglutinin-Esterase Lectin Activity.; Cell Host Microbe, 21:356-366, 2017; PubMed: 28279346; DOI: 10.1016/j.chom.2017.02.008

Experimental method

X-RAY DIFFRACTION (2.45 Å)