7VKC
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7VKB
| Crystal structure of the a bacterial kinase complex | 分子名称: | DI(HYDROXYETHYL)ETHER, HipA (Persistence to inhibition of murein or DNA biosynthesis), HipA_C domain-containing protein, ... | 著者 | Zhen, X, Ouyang, S.Y. | 登録日 | 2021-09-29 | 公開日 | 2022-06-29 | 最終更新日 | 2022-08-03 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila. Nat Commun, 13, 2022
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8IFO
| Crystal structure of estrogen related receptor-gamma DNA binding domain complexed with Pla2g12b promoter | 分子名称: | DNA (5'-D(*GP*AP*GP*GP*AP*CP*AP*AP*AP*GP*GP*TP*GP*AP*AP*AP*C)-3'), DNA (5'-D(*GP*TP*TP*TP*CP*AP*CP*CP*TP*TP*TP*GP*TP*CP*CP*TP*C)-3'), Estrogen-related receptor gamma, ... | 著者 | Xu, T, Zhen, X, Liu, J. | 登録日 | 2023-02-19 | 公開日 | 2023-03-29 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | ERR gamma-DBD undergoes dimerization and conformational rearrangement upon binding to the downstream site of the DR1 element. Biochem.Biophys.Res.Commun., 656, 2023
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5H5P
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6IPX
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7D55
| Crystal structure of lys170 CBD | 分子名称: | Putative N-acetylmuramoyl-L-alanine amidase | 著者 | Zhen, X. | 登録日 | 2020-09-25 | 公開日 | 2021-06-09 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.397 Å) | 主引用文献 | Structural and biochemical analyses of the tetrameric cell binding domain of Lys170 from enterococcal phage F170/08. Eur.Biophys.J., 50, 2021
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8JL0
| Cryo-EM structure of the prokaryotic SPARSA system complex | 分子名称: | DNA (5'-D(P*AP*CP*GP*AP*CP*GP*TP*CP*TP*AP*AP*GP*AP*AP*AP*CP*CP*AP*TP*TP*AP*T)-3'), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Piwi domain protein, ... | 著者 | Xu, X, Zhen, X, Long, F. | 登録日 | 2023-06-02 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of antiphage immunity generated by a prokaryotic Argonaute-associated SPARSA system. Nat Commun, 15, 2024
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8JKZ
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7XUX
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7W54
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7WCF
| Crystal structure of the kinase with AMP-PNP | 分子名称: | HipA_C domain-containing protein, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | 著者 | Ouyang, S.Y, Zhen, X. | 登録日 | 2021-12-20 | 公開日 | 2022-06-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.3636 Å) | 主引用文献 | Molecular mechanism of toxin neutralization in the HipBST toxin-antitoxin system of Legionella pneumophila. Nat Commun, 13, 2022
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6IM4
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7BXO
| Crystal structure of the toxin-antitoxin with AMP-PNP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Toxin-antitoxin system antidote Mnt family, ... | 著者 | Ouyang, S.Y, Zhen, X.K. | 登録日 | 2020-04-20 | 公開日 | 2020-09-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.77 Å) | 主引用文献 | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system. Nucleic Acids Res., 48, 2020
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6L00
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6M6U
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6M6W
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6M6V
| Crystal structure the toxin-antitoxin MntA-HepT | 分子名称: | RNA (5'-R(P*AP*AP*A)-3'), Toxin-antitoxin system antidote Mnt family, Toxin-antitoxin system toxin HepN family | 著者 | Ouyang, S.Y, Zhen, X.K. | 登録日 | 2020-03-16 | 公開日 | 2020-09-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | 主引用文献 | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system. Nucleic Acids Res., 48, 2020
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8X3S
| Crystal structure of human WDR5 in complex with PTEN | 分子名称: | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, WD repeat-containing protein 5 | 著者 | Liu, Y, Huang, X, Shang, X. | 登録日 | 2023-11-14 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | The NTE domain of PTEN alpha / beta promotes cancer progression by interacting with WDR5 via its SSSRRSS motif. Cell Death Dis, 15, 2024
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6V9T
| Tudor domain of TDRD3 in complex with a small molecule | 分子名称: | 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, Tudor domain-containing protein 3, UNKNOWN ATOM OR ION | 著者 | Li, W, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2019-12-16 | 公開日 | 2019-12-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.154 Å) | 主引用文献 | A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nat Commun, 13, 2022
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8X3R
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7BU0
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4QQ6
| Crystal Structure of tudor domain of SMN1 in complex with a small organic molecule | 分子名称: | 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, Survival motor neuron protein, UNKNOWN ATOM OR ION | 著者 | Liu, Y, Tempel, W, Iqbal, A, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2014-06-26 | 公開日 | 2014-08-06 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nat Commun, 13, 2022
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4QQD
| Crystal Structure of tandem tudor domains of UHRF1 in complex with a small organic molecule | 分子名称: | 4-methyl-2,3,4,5,6,7-hexahydrodicyclopenta[b,e]pyridin-8(1H)-imine, E3 ubiquitin-protein ligase UHRF1, UNKNOWN ATOM OR ION | 著者 | Liu, Y, Tempel, W, Iqbal, A, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2014-06-27 | 公開日 | 2014-08-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nat Commun, 13, 2022
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7YP6
| Crystal structure of elaiophylin glycosyltransferase in complex with UDP | 分子名称: | Glycosyltransferase, R-1,2-PROPANEDIOL, URIDINE-5'-DIPHOSPHATE | 著者 | Xu, T, Liu, Q, Gan, Q, Liu, J. | 登録日 | 2022-08-02 | 公開日 | 2022-11-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Substrate-induced dimerization of elaiophylin glycosyltransferase reveals a novel self-activating form of glycosyltransferase for symmetric glycosylation. Acta Crystallogr D Struct Biol, 78, 2022
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7YP3
| Crystal structure of elaiophylin glycosyltransferase in complex with elaiophylin | 分子名称: | ACETATE ION, Elaiophylin, GLYCEROL, ... | 著者 | Xu, T, Liu, Q, Gan, Q, Liu, J. | 登録日 | 2022-08-02 | 公開日 | 2022-11-02 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Substrate-induced dimerization of elaiophylin glycosyltransferase reveals a novel self-activating form of glycosyltransferase for symmetric glycosylation. Acta Crystallogr D Struct Biol, 78, 2022
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