Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6IJX

Crystal Structure of AKR1C1 complexed with meclofenamic acid

Summary for 6IJX
Entry DOI10.2210/pdb6ijx/pdb
Related6A7A 6A7B
DescriptorAldo-keto reductase family 1 member C1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-[(2,6-dichloro-3-methyl-phenyl)amino]benzoic acid, ... (4 entities in total)
Functional Keywordsinhibitor, complex, oxidoreductase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight37878.89
Authors
Zheng, X.,Zhao, Y.,Zhang, L.,Zhang, H.,Chen, Y.,Hu, X. (deposition date: 2018-10-12, release date: 2019-10-16, Last modification date: 2023-11-22)
Primary citationZheng, X.,Jiang, Z.,Li, X.,Zhang, C.,Li, Z.,Wu, Y.,Wang, X.,Zhang, C.,Luo, H.B.,Xu, J.,Wu, D.
Screening, synthesis, crystal structure, and molecular basis of 6-amino-4-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles as novel AKR1C3 inhibitors.
Bioorg.Med.Chem., 26:5934-5943, 2018
Cited by
PubMed: 30429100
DOI: 10.1016/j.bmc.2018.10.044
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon