2LSP
 
 | | solution structures of BRD4 second bromodomain with NF-kB-K310ac peptide | | 分子名称: | Bromodomain-containing protein 4, NF-kB-K310ac peptide | | 著者 | Zhang, G, Liu, R, Zhong, Y, Plotnikov, A.N, Zhang, W, Rusinova, E, Gerona-Nevarro, G, Moshkina, N, Joshua, J, Chuang, P.Y, Ohlmeyer, M, He, J, Zhou, M.-M. | | 登録日 | 2012-05-03 | | 公開日 | 2012-07-18 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Down-regulation of NF-kappa B transcriptional activity in HIV-associated kidney disease by BRD4 inhibition.
J.Biol.Chem., 287, 2012
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1SWV
 | | Crystal structure of the D12A mutant of phosphonoacetaldehyde hydrolase complexed with magnesium | | 分子名称: | MAGNESIUM ION, phosphonoacetaldehyde hydrolase | | 著者 | Zhang, G, Morais, M.C, Dai, J, Zhang, W, Dunaway-Mariano, D, Allen, K.N. | | 登録日 | 2004-03-30 | | 公開日 | 2004-10-05 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Investigation of metal ion binding in phosphonoacetaldehyde hydrolase identifies sequence markers for metal-activated enzymes of the HAD enzyme superfamily
Biochemistry, 43, 2004
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1SWW
 | | Crystal structure of the phosphonoacetaldehyde hydrolase D12A mutant complexed with magnesium and substrate phosphonoacetaldehyde | | 分子名称: | MAGNESIUM ION, PHOSPHONOACETALDEHYDE, phosphonoacetaldehyde hydrolase | | 著者 | Zhang, G, Morais, M.C, Dai, J, Zhang, W, Dunaway-Mariano, D, Allen, K.N. | | 登録日 | 2004-03-30 | | 公開日 | 2004-10-05 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Investigation of metal ion binding in phosphonoacetaldehyde hydrolase identifies sequence markers for metal-activated enzymes of the HAD enzyme superfamily
Biochemistry, 43, 2004
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1PTQ
 | | PROTEIN KINASE C DELTA CYS2 DOMAIN | | 分子名称: | PROTEIN KINASE C DELTA TYPE, ZINC ION | | 著者 | Zhang, G, Hurley, J.H. | | 登録日 | 1995-05-11 | | 公開日 | 1995-07-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester.
Cell(Cambridge,Mass.), 81, 1995
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1PTR
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1ZOL
 | | native beta-PGM | | 分子名称: | MAGNESIUM ION, beta-phosphoglucomutase | | 著者 | Zhang, G, Tremblay, L.W, Dai, J, Wang, L, Dunaway-Mariano, D, Allen, K.N. | | 登録日 | 2005-05-13 | | 公開日 | 2005-08-30 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Catalytic cycling in beta-phosphoglucomutase: a kinetic and structural analysis
Biochemistry, 44, 2005
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1AB8
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1BDF
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7F0X
 | | A SARS-CoV-2 neutralizing antibody | | 分子名称: | Antibody, Spike protein S1 | | 著者 | Zhang, G, Li, X, Guo, Y, Wang, Y, Yuan, S. | | 登録日 | 2021-06-07 | | 公開日 | 2022-06-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A SARS-CoV-2 neutralizing
antibody
To Be Published
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7F12
 | | A SARS-CoV-2 neutralizing antibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody, Spike protein S1 | | 著者 | Zhang, G, Li, X, Guo, Y, Wang, Y, Yuan, S. | | 登録日 | 2021-06-07 | | 公開日 | 2022-06-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | A SARS-CoV-2 neutralizing
antibody
To Be Published
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7F15
 | | A SARS-CoV-2 neutralizing antibody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody, Spike protein S1 | | 著者 | Zhang, G, Li, X, Guo, Y, Wang, Y, Yuan, S. | | 登録日 | 2021-06-07 | | 公開日 | 2022-06-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | A SARS-CoV-2 neutralizing
antibody
To Be Published
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1OQD
 | | Crystal structure of sTALL-1 and BCMA | | 分子名称: | Tumor necrosis factor ligand superfamily member 13B, soluble form, Tumor necrosis factor receptor superfamily member 17 | | 著者 | Zhang, G. | | 登録日 | 2003-03-07 | | 公開日 | 2003-05-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Ligand-receptor binding revealed by the TNF family member TALL-1.
Nature, 423, 2003
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1OQE
 | | Crystal structure of sTALL-1 with BAFF-R | | 分子名称: | Tumor necrosis factor ligand superfamily member 13B, soluble form, Tumor necrosis factor receptor superfamily member 13C | | 著者 | Zhang, G. | | 登録日 | 2003-03-07 | | 公開日 | 2003-05-13 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Ligand-receptor binding revealed by the TNF family member TALL-1.
Nature, 423, 2003
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8IL3
 | | Cryo-EM structure of CD38 in complex with FTL004 | | 分子名称: | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Heavy chain, Light chain | | 著者 | Yang, J, Wang, Y, Zhang, G. | | 登録日 | 2023-03-01 | | 公開日 | 2023-03-29 | | 実験手法 | ELECTRON MICROSCOPY (3.86 Å) | | 主引用文献 | FTL004, an anti-CD38 mAb with negligible RBC binding and enhanced pro-apoptotic activity, is a novel candidate for treatments of multiple myeloma and non-Hodgkin lymphoma.
J Hematol Oncol, 15, 2022
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1HSJ
 | | SARR MBP FUSION STRUCTURE | | 分子名称: | FUSION PROTEIN CONSISTING OF STAPHYLOCOCCUS ACCESSORY REGULATOR PROTEIN R AND MALTOSE BINDING PROTEIN, alpha-D-glucopyranose | | 著者 | Zhang, G. | | 登録日 | 2000-12-26 | | 公開日 | 2001-06-06 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the SarR protein from Staphylococcus aureus.
Proc.Natl.Acad.Sci.USA, 98, 2001
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2P5B
 | | The complex structure of JMJD2A and trimethylated H3K36 peptide | | 分子名称: | FE (II) ION, Histone H3, JmjC domain-containing histone demethylation protein 3A, ... | | 著者 | Zhang, G, Chen, Z, Zang, J, Hong, X, Shi, Y. | | 登録日 | 2007-03-14 | | 公開日 | 2007-06-12 | | 最終更新日 | 2013-11-27 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Structural basis of the recognition of a methylated histone tail by JMJD2A.
Proc.Natl.Acad.Sci.USA, 104, 2007
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6R8I
 | | PP4R3A EVH1 domain bound to FxxP motif | | 分子名称: | SER-LEU-PRO-PHE-THR-PHE-LYS-VAL-PRO-ALA-PRO-PRO-PRO-SER-LEU-PRO-PRO-SER, Serine/threonine-protein phosphatase 4 regulatory subunit 3A | | 著者 | Ueki, Y, Kruse, T, Weisser, M.B, Sundell, G.N, Yoo Larsen, M.S, Lopez Mendez, B, Jenkins, N.P, Garvanska, D.H, Cressey, L, Zhang, G, Davey, N, Montoya, G, Ivarsson, Y, Kettenbach, A, Nilsson, J. | | 登録日 | 2019-04-02 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.517 Å) | | 主引用文献 | A Consensus Binding Motif for the PP4 Protein Phosphatase.
Mol.Cell, 76, 2019
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7DEU
 | | Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody scFv | | 著者 | Zhang, Z, Zhang, G, Li, X, Rao, Z, Guo, Y. | | 登録日 | 2020-11-05 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes.
Plos Biol., 19, 2021
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7DEO
 | | Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Spike protein S1, ... | | 著者 | Fu, D, Zhang, G, Li, X, Rao, Z, Guo, Y. | | 登録日 | 2020-11-04 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes.
Plos Biol., 19, 2021
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7DET
 | | Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody scFv | | 著者 | Wang, Y, Zhang, G, Li, X, Rao, Z, Guo, Y. | | 登録日 | 2020-11-05 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes.
Plos Biol., 19, 2021
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2GDL
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5HRJ
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1FEZ
 | | THE CRYSTAL STRUCTURE OF BACILLUS CEREUS PHOSPHONOACETALDEHYDE HYDROLASE COMPLEXED WITH TUNGSTATE, A PRODUCT ANALOG | | 分子名称: | MAGNESIUM ION, PHOSPHONOACETALDEHYDE HYDROLASE, TUNGSTATE(VI)ION | | 著者 | Morais, M.C, Zhang, W, Baker, A.S, Zhang, G, Dunaway-Mariano, D, Allen, K.N. | | 登録日 | 2000-07-24 | | 公開日 | 2000-10-04 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The crystal structure of bacillus cereus phosphonoacetaldehyde hydrolase: insight into catalysis of phosphorus bond cleavage and catalytic diversification within the HAD enzyme superfamily.
Biochemistry, 39, 2000
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2W7X
 | | Cellular inhibition of checkpoint kinase 2 and potentiation of cytotoxic drugs by novel Chk2 inhibitor PV1019 | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, N-[4-[(E)-N-carbamimidamido-C-methyl-carbonimidoyl]phenyl]-7-nitro-1H-indole-2-carboxamide, ... | | 著者 | Jobson, A.G, Lountos, G.T, Lorenzi, P.L, Llamas, J, Connelly, J, Tropea, J.E, Onda, A, Kondapaka, S, Zhang, G, Caplen, N.J, Caredellina, J.H, Monks, A, Self, C, Waugh, D.S, Shoemaker, R.H, Pommier, Y. | | 登録日 | 2009-01-06 | | 公開日 | 2009-09-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Cellular Inhibition of Chk2 Kinase and Potentiation of Camptothecins and Radiation by the Novel Chk2 Inhibitor Pv1019.
J.Pharmacol.Exp.Ther., 331, 2009
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6LM2
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