6AHD
 
 | | The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Brr2, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... | | 著者 | Zhan, X, Yan, C, Zhang, X, Shi, Y. | | 登録日 | 2018-08-17 | | 公開日 | 2018-11-14 | | 最終更新日 | 2021-06-30 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018
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7EVN
 | | The cryo-EM structure of the DDX42-SF3b complex | | 分子名称: | ATP-dependent RNA helicase DDX42, PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, ... | | 著者 | Zhang, X, Zhan, X, Shi, Y. | | 登録日 | 2021-05-21 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural insights into branch site proofreading by human spliceosome
Nat.Struct.Mol.Biol., 2024
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7EVO
 | | The cryo-EM structure of the human 17S U2 snRNP | | 分子名称: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, RNA helicase, ... | | 著者 | Zhang, X, Zhan, X, Shi, Y. | | 登録日 | 2021-05-21 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Structural insights into branch site proofreading by human spliceosome.
Nat.Struct.Mol.Biol., 2024
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5Z58
 | | Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | | 登録日 | 2018-01-17 | | 公開日 | 2018-09-19 | | 最終更新日 | 2020-10-14 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
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5Z56
 | | cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | | 登録日 | 2018-01-17 | | 公開日 | 2018-09-19 | | 最終更新日 | 2020-10-14 | | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | | 主引用文献 | Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
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5Z57
 | | Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ALANINE, BUD13 homolog, ... | | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | | 登録日 | 2018-01-17 | | 公開日 | 2018-09-19 | | 最終更新日 | 2020-10-14 | | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | | 主引用文献 | Structure of the human activated spliceosome in three conformational states.
Cell Res., 28, 2018
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5YZG
 | | The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Zhan, X, Yan, C, Zhang, X, Lei, J, Shi, Y. | | 登録日 | 2017-12-14 | | 公開日 | 2018-08-08 | | 最終更新日 | 2020-10-14 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structure of a human catalytic step I spliceosome
Science, 359, 2018
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6AH0
 | | The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | | 著者 | Zhan, X, Yan, C, Zhang, X, Shi, Y. | | 登録日 | 2018-08-15 | | 公開日 | 2018-11-14 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | | 主引用文献 | Structures of the human pre-catalytic spliceosome and its precursor spliceosome.
Cell Res., 28, 2018
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6ID1
 | | Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | | 著者 | Zhang, X, Zhan, X, Yan, C, Shi, Y. | | 登録日 | 2018-09-07 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-10-14 | | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | | 主引用文献 | Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
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6ID0
 | | Cryo-EM structure of a human intron lariat spliceosome prior to Prp43 loaded (ILS1 complex) at 2.9 angstrom resolution | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | | 著者 | Zhang, X, Zhan, X, Yan, C, Shi, Y. | | 登録日 | 2018-09-07 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-10-14 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
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6ICZ
 | | Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | | 著者 | Zhang, X, Zhan, X, Yan, C, Shi, Y. | | 登録日 | 2018-09-07 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-10-14 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
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8HMY
 | | Cryo-EM structure of the human pre-catalytic TSEN/pre-tRNA complex | | 分子名称: | Chromosome 1 open reading frame 19, isoform CRA_a, MAGNESIUM ION, ... | | 著者 | Zhang, X, Yang, F, Zhan, X, Shi, Y. | | 登録日 | 2022-12-06 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease.
Mol.Cell, 83, 2023
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8HMZ
 | | Cryo-EM structure of the human post-catalytic TSEN/pre-tRNA complex | | 分子名称: | Chromosome 1 open reading frame 19, isoform CRA_a, MAGNESIUM ION, ... | | 著者 | Zhang, X, Yang, F, Zhan, X, Shi, Y. | | 登録日 | 2022-12-06 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of pre-tRNA intron removal by human tRNA splicing endonuclease.
Mol.Cell, 83, 2023
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7VPX
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7W5B
 | | The cryo-EM structure of human C* complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | | 著者 | Zhan, X, Lu, Y, Shi, Y. | | 登録日 | 2021-11-29 | | 公開日 | 2022-06-22 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
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7W5A
 | | The cryo-EM structure of human pre-C*-II complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | | 著者 | Zhan, X, Lu, Y, Shi, Y. | | 登録日 | 2021-11-29 | | 公開日 | 2022-06-22 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
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7W59
 | | The cryo-EM structure of human pre-C*-I complex | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent RNA helicase DHX8, ... | | 著者 | Zhan, X, Lu, Y, Shi, Y. | | 登録日 | 2021-11-29 | | 公開日 | 2022-06-22 | | 最終更新日 | 2022-08-17 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Mechanism of exon ligation by human spliceosome.
Mol.Cell, 82, 2022
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4GJT
 | | complex structure of nectin-4 bound to MV-H | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin glycoprotein, Poliovirus receptor-related protein 4 | | 著者 | Zhang, X, Lu, G, Qi, J, Li, Y, He, Y, Xu, X, Shi, J, Zhang, C, Yan, J, Gao, G.F. | | 登録日 | 2012-08-10 | | 公開日 | 2012-10-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.1001 Å) | | 主引用文献 | Structure of measles virus hemagglutinin bound to its epithelial receptor nectin-4
Nat.Struct.Mol.Biol., 20, 2013
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5HWL
 | | Human glutathione s-transferase Mu2 complexed with BDEA, monoclinic crystal form | | 分子名称: | GLUTATHIONE, Glutathione S-transferase Mu 2, N,N'-(butane-1,4-diyl)bis{2-[2,3-dichloro-4-(2-methylidenebutanoyl)phenoxy]acetamide} | | 著者 | Zhang, X, Wei, J, Wu, S, Zhang, H.P, Luo, M, Yang, X.L, Liao, F, Wang, D.Q. | | 登録日 | 2016-01-29 | | 公開日 | 2017-11-08 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Human glutathione s-transferase Mu2 complexed with BDEA, monoclinic crystal form
To Be Published
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2RF9
 | | Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide | | 分子名称: | ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor | | 著者 | Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J. | | 登録日 | 2007-09-28 | | 公開日 | 2007-12-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.
Nature, 450, 2007
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2RFE
 | | Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide | | 分子名称: | ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor | | 著者 | Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J. | | 登録日 | 2007-09-28 | | 公開日 | 2007-12-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.
Nature, 450, 2007
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2GS6
 | | Crystal Structure of the active EGFR kinase domain in complex with an ATP analog-peptide conjugate | | 分子名称: | CHLORIDE ION, Epidermal growth factor receptor, Peptide, ... | | 著者 | Zhang, X, Gureasko, J, Shen, K, Cole, P.A, Kuriyan, J. | | 登録日 | 2006-04-25 | | 公開日 | 2006-06-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor
Cell(Cambridge,Mass.), 125, 2006
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1ML9
 | | Structure of the Neurospora SET domain protein DIM-5, a histone lysine methyltransferase | | 分子名称: | Histone H3 methyltransferase DIM-5, UNKNOWN, ZINC ION | | 著者 | Zhang, X, Tamaru, H, Khan, S.I, Horton, J.R, Keefe, L.J, Selker, E.U, Cheng, X. | | 登録日 | 2002-08-30 | | 公開日 | 2002-10-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structure of the Neurospora SET domain protein DIM-5,
a histone H3 lysine methyltransferase
Cell(Cambridge,Mass.), 111, 2002
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1F3L
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1KJS
 | | NMR SOLUTION STRUCTURE OF C5A AT PH 5.2, 303K, 20 STRUCTURES | | 分子名称: | C5A | | 著者 | Zhang, X, Boyar, W, Toth, M, Wennogle, L, Gonnella, N.C. | | 登録日 | 1997-01-09 | | 公開日 | 1997-05-15 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural definition of the C5a C terminus by two-dimensional nuclear magnetic resonance spectroscopy.
Proteins, 28, 1997
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