7V6K
 
 | | Crystal structure of Sortase A from Streptococcus pyogenes in complex with ML346 | | 分子名称: | 5-[3-(4-methoxyphenyl)prop-2-enylidene]-1,3-diazinane-2,4,6-trione, MAGNESIUM ION, Sortase | | 著者 | Yang, C.G, Gan, J. | | 登録日 | 2021-08-20 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Covalent sortase A inhibitor ML346 prevents Staphylococcus aureus infection of Galleria mellonella.
Rsc Med Chem, 13, 2022
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4MG2
 | | ALKBH2 F102A cross-linked to undamaged dsDNA | | 分子名称: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA-1, DNA-2, ... | | 著者 | Chen, B, Gan, J, Yang, C.G. | | 登録日 | 2013-08-28 | | 公開日 | 2014-02-26 | | 最終更新日 | 2014-06-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The complex structures of ALKBH2 mutants cross-linked to
dsDNA reveal the conformational swing of β-hairpin
Sci China Chem, 57, 2014
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4ZS3
 | | Structural complex of 5-aminofluorescein bound to the FTO protein | | 分子名称: | 2-OXOGLUTARIC ACID, 5-amino-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid, Alpha-ketoglutarate-dependent dioxygenase FTO, ... | | 著者 | Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X. | | 登録日 | 2015-05-13 | | 公開日 | 2015-11-04 | | 最終更新日 | 2015-11-18 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein
J.Am.Chem.Soc., 137, 2015
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4ZS2
 | | Structural complex of FTO/fluorescein | | 分子名称: | 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID, 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase FTO, ... | | 著者 | Wang, T, Hong, T, Huang, Y, Yang, C.G, Zhou, X. | | 登録日 | 2015-05-13 | | 公開日 | 2015-11-04 | | 最終更新日 | 2015-11-18 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein
J.Am.Chem.Soc., 137, 2015
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3OLJ
 | | Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) | | 分子名称: | Ribonucleoside-diphosphate reductase subunit M2, SODIUM ION | | 著者 | Chen, X.H, Xu, Z.J, Chen, B.E, Jiang, H.J, Yang, C.G, Zhu, W.L, Shao, J.M. | | 登録日 | 2010-08-26 | | 公開日 | 2011-08-31 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | hRRM2
To be Published
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4MGT
 | | ALKBH2 R110A cross-linked to undamaged dsDNA | | 分子名称: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA1, DNA2, ... | | 著者 | Chen, B, Gan, J, Yang, C.G. | | 登録日 | 2013-08-28 | | 公開日 | 2014-02-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The complex structures of ALKBH2 mutants cross-linked to
dsDNA reveal the conformational swing of β-hairpin
Sci China Chem, 57, 2014
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5HLG
 | | Structure of reduced AbfR bound to DNA | | 分子名称: | DNA (5'-D(*TP*AP*AP*CP*TP*CP*AP*AP*TP*CP*GP*CP*GP*CP*GP*CP*GP*AP*TP*TP*GP*AP*GP*T)-3'), MarR family transcriptional regulator | | 著者 | Liu, G, Liu, X, Gan, J, Yang, C.G. | | 登録日 | 2016-01-15 | | 公開日 | 2017-01-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural Insights into the Redox-Sensing Mechanism of MarR-Type Regulator AbfR.
J. Am. Chem. Soc., 139, 2017
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4QBA
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3BTY
 | | Crystal structure of human ABH2 bound to dsDNA containing 1meA through cross-linking away from active site | | 分子名称: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA (5'-D(*DCP*DTP*DGP*DTP*DAP*DTP*(MA7)P*DAP*DCP*DTP*DGP*DCP*DG)-3'), DNA (5'-D(*DTP*DCP*DGP*DCP*DAP*DGP*DTP*DTP*DAP*DTP*DAP*DCP*DA)-3'), ... | | 著者 | Yang, C.-G, Yi, C, He, C. | | 登録日 | 2007-12-31 | | 公開日 | 2008-04-22 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
Nature, 452, 2008
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3BTZ
 | | Crystal structure of human ABH2 cross-linked to dsDNA | | 分子名称: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA (5'-D(*AP*GP*GP*TP*GP*AP*(2YR)P*AP*AP*TP*GP*CP*G)-3'), DNA (5'-D(*DTP*DCP*DGP*DCP*DAP*DTP*DTP*DAP*DTP*DCP*DAP*DCP*DC)-3') | | 著者 | Yang, C.-G, Yi, C, He, C. | | 登録日 | 2007-12-31 | | 公開日 | 2008-04-22 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
Nature, 452, 2008
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3BUC
 | | X-ray structure of human ABH2 bound to dsDNA with Mn(II) and 2KG | | 分子名称: | 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA (5'-D(*DCP*DTP*DGP*DTP*DAP*DTP*(MA7)P*DAP*DCP*DTP*DGP*DCP*DG)-3'), ... | | 著者 | Yang, C.-G, Yi, C, He, C. | | 登録日 | 2008-01-02 | | 公開日 | 2008-04-22 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
Nature, 452, 2008
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3BI3
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3BTX
 | | X-ray structure of human ABH2 bound to dsDNA through active site cross-linking | | 分子名称: | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA (5'-D(*CP*TP*GP*TP*AP*TP*(2YR)P*AP*TP*TP*GP*CP*G)-3'), DNA (5'-D(*DTP*DCP*DGP*DCP*DAP*DAP*DTP*DAP*DAP*DTP*DAP*DCP*DA)-3'), ... | | 著者 | Yang, C.-G, Yi, C, He, C. | | 登録日 | 2007-12-31 | | 公開日 | 2008-04-22 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
Nature, 452, 2008
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3BU0
 | | crystal structure of human ABH2 cross-linked to dsDNA with cofactors | | 分子名称: | 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA (5'-D(*CP*TP*GP*TP*AP*TP*(2YR)P*AP*TP*TP*GP*CP*G)-3'), ... | | 著者 | Yang, C.-G, Yi, C, He, C. | | 登録日 | 2007-12-31 | | 公開日 | 2008-04-22 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
Nature, 452, 2008
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6IHR
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6IHS
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6IHL
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6IHW
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6IHT
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6IHU
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6IHV
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4RFR
 | | Complex structure of AlkB/rhein | | 分子名称: | 4,5-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid, Alpha-ketoglutarate-dependent dioxygenase AlkB, MANGANESE (II) ION | | 著者 | Li, Q, Huang, Y, Li, J.F, Yang, C.-G. | | 登録日 | 2014-09-27 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Rhein Inhibits AlkB Repair Enzymes and Sensitizes Cells to Methylated DNA Damage.
J.Biol.Chem., 291, 2016
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3O1U
 | | Iron-Catalyzed Oxidation Intermediates Captured in A DNA Repair Dioxygenase | | 分子名称: | Alpha-ketoglutarate-dependent dioxygenase AlkB, DNA (5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*TP*AP*AP*(MDV)P*AP*CP*CP*GP*T)-3'), ... | | 著者 | Yi, C, Jia, G, Hou, G, Dai, Q, Zhang, W, Zheng, G, Jian, X, Yang, C.-G, Cui, Q, He, C. | | 登録日 | 2010-07-22 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.
Nature, 468, 2010
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3O1S
 | | Iron-Catalyzed Oxidation Intermediates Captured in A DNA Repair Dioxygenase | | 分子名称: | Alpha-ketoglutarate-dependent dioxygenase AlkB, DNA (5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*TP*AP*AP*(MDQ)P*AP*CP*CP*GP*T)-3'), ... | | 著者 | Yi, C, Jia, G, Hou, G, Dai, Q, Zhang, W, Zheng, G, Jian, X, Yang, C.-G, Cui, Q, He, C. | | 登録日 | 2010-07-22 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.
Nature, 468, 2010
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3O1T
 | | Iron-Catalyzed Oxidation Intermediates Captured in A DNA Repair Dioxygenase | | 分子名称: | Alpha-ketoglutarate-dependent dioxygenase AlkB, DNA (5'-D(*AP*AP*CP*GP*GP*TP*AP*TP*TP*AP*CP*CP*T)-3'), DNA (5'-D(*AP*GP*GP*TP*AP*AP*(MDU)P*AP*CP*CP*GP*T)-3'), ... | | 著者 | Yi, C, Jia, G, Hou, G, Dai, Q, Zhang, W, Zheng, G, Jian, X, Yang, C.-G, Cui, Q, He, C. | | 登録日 | 2010-07-22 | | 公開日 | 2010-11-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.
Nature, 468, 2010
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