3BTX

X-ray structure of human ABH2 bound to dsDNA through active site cross-linking

Summary for 3BTX

• Entry DOI: 10.2210/pdb3btx/pdb
• Related: 2FD8 2IUW 3BTY 3BTZ 3BU0 3BUC
• Descriptor: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, DNA (5'-D(*CP*TP*GP*TP*AP*TP*(2YR)P*AP*TP*TP*GP*CP*G)-3'), DNA (5'-D(*DTP*DCP*DGP*DCP*DAP*DAP*DTP*DAP*DAP*DTP*DAP*DCP*DA)-3'), ... (5 entities in total)
• Functional Keywords: protein/dna interaction, human dioxygenase, dna repair, cross-linking, dna damage, iron, metal-binding, nucleus, oxidoreductase, oxidoreductase-dna complex, oxidoreductase/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: Q6NS38
• Total number of polymer chains: 3
• Total formula weight: 31121.05

Authors

Yang, C.-G.,Yi, C.,He, C. (deposition date: 2007-12-31, release date: 2008-04-22, Last modification date: 2021-10-20)

• Primary citation: Yang, C.G.,Yi, C.,Duguid, E.M.,Sullivan, C.T.,Jian, X.,Rice, P.A.,He, C.; Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.; Nature, 452:961-965, 2008; PubMed: 18432238; DOI: 10.1038/nature06889

Experimental method

X-RAY DIFFRACTION (2 Å)