3BTY
Crystal structure of human ABH2 bound to dsDNA containing 1meA through cross-linking away from active site
Summary for 3BTY
| Entry DOI | 10.2210/pdb3bty/pdb |
| Related | 2FD8 2IUW 3BTX 3BTZ 3BU0 3BUC |
| Descriptor | DNA (5'-D(*DCP*DTP*DGP*DTP*DAP*DTP*(MA7)P*DAP*DCP*DTP*DGP*DCP*DG)-3'), DNA (5'-D(*DTP*DCP*DGP*DCP*DAP*DGP*DTP*DTP*DAP*DTP*DAP*DCP*DA)-3'), Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, ... (5 entities in total) |
| Functional Keywords | protein/dna interaction, human dioxygenase, dna repair, cross-linking, dna damage, iron, metal-binding, nucleus, oxidoreductase, oxidoreductase-dna complex, oxidoreductase/dna |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus: Q6NS38 |
| Total number of polymer chains | 3 |
| Total formula weight | 31144.80 |
| Authors | Yang, C.-G.,Yi, C.,He, C. (deposition date: 2007-12-31, release date: 2008-04-22, Last modification date: 2021-10-20) |
| Primary citation | Yang, C.G.,Yi, C.,Duguid, E.M.,Sullivan, C.T.,Jian, X.,Rice, P.A.,He, C. Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA. Nature, 452:961-965, 2008 Cited by PubMed: 18432238DOI: 10.1038/nature06889 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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