3BTY
Crystal structure of human ABH2 bound to dsDNA containing 1meA through cross-linking away from active site
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | DNA (5'-D(*DCP*DTP*DGP*DTP*DAP*DTP*(MA7)P*DAP*DCP*DTP*DGP*DCP*DG)-3') | polymer | 13 | 3981.6 | 1 | |||
| 2 | B (C) | DNA (5'-D(*DTP*DCP*DGP*DCP*DAP*DGP*DTP*DTP*DAP*DTP*DAP*DCP*DA)-3') | polymer | 13 | 3950.6 | 1 | |||
| 3 | C (A) | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 | polymer | 203 | 23136.4 | 1 | UniProt (Q6NS38) Pfam (PF13532) | Homo sapiens (human) | Alkylated DNA repair protein alkB homolog 2, Oxy DC1 |
| 4 | D (B) | propane-1-thiol | non-polymer | 76.2 | 1 | Chemie (XL3) | |||
| 5 | E, F, G (B, C, A) | water | water | 18.0 | 124 | Chemie (HOH) |
Sequence modifications
A: 56 - 258 (UniProt: Q6NS38)
| PDB | External Database | Details |
|---|---|---|
| Ser 67 | Cys 67 | engineered mutation |
| Ser 165 | Cys 165 | engineered mutation |
| Cys 169 | Gly 169 | engineered mutation |
| Ser 192 | Cys 192 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 31068.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 76.2 | |
| All* | Total formula weight | 31144.8 |
