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6WLH
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BU of 6wlh by Molmil
RNA complex of WT1 zinc finger transcription factor
分子名称: RNA (29-MER), Wilms tumor protein, ZINC ION
著者Wright, P.E, Dyson, H.J.
登録日2020-04-20
公開日2021-03-03
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献RNA Binding by the KTS Splice Variants of Wilms' Tumor Suppressor Protein WT1.
Biochemistry, 59, 2020
1F68
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BU of 1f68 by Molmil
NMR SOLUTION STRUCTURE OF THE BROMODOMAIN FROM HUMAN GCN5
分子名称: HISTONE ACETYLTRANSFERASE
著者Wright, P.E, Hudson, B.P, Dyson, H.J.
登録日2000-06-20
公開日2000-12-13
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure and acetyl-lysine binding activity of the GCN5 bromodomain.
J.Mol.Biol., 304, 2000
9PCY
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BU of 9pcy by Molmil
HIGH-RESOLUTION SOLUTION STRUCTURE OF REDUCED FRENCH BEAN PLASTOCYANIN AND COMPARISON WITH THE CRYSTAL STRUCTURE OF POPLAR PLASTOCYANIN
分子名称: COPPER (II) ION, PLASTOCYANIN
著者Moore, J.M, Lepre, C.A, Gippert, G.P, Chazin, W.J, Case, D.A, Wright, P.E.
登録日1991-03-18
公開日1993-10-31
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献High-resolution solution structure of reduced French bean plastocyanin and comparison with the crystal structure of poplar plastocyanin.
J.Mol.Biol., 221, 1991
1R8U
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BU of 1r8u by Molmil
NMR structure of CBP TAZ1/CITED2 complex
分子名称: CREB-binding protein, Cbp/p300-interacting transactivator 2, ZINC ION
著者De Guzman, R.N, Martinez-Yamout, M, Dyson, H.J, Wright, P.E.
登録日2003-10-28
公開日2004-03-23
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites.
J.Biol.Chem., 279, 2004
1XOB
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BU of 1xob by Molmil
THIOREDOXIN (REDUCED DITHIO FORM), NMR, 20 STRUCTURES
分子名称: THIOREDOXIN
著者Jeng, M.-F, Campbell, A.P, Begley, T, Holmgren, A, Case, D.A, Wright, P.E, Dyson, H.J.
登録日1995-11-28
公開日1996-06-10
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献High-resolution solution structures of oxidized and reduced Escherichia coli thioredoxin.
Structure, 2, 1994
1XOA
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BU of 1xoa by Molmil
THIOREDOXIN (OXIDIZED DISULFIDE FORM), NMR, 20 STRUCTURES
分子名称: THIOREDOXIN
著者Jeng, M.-F, Campbell, A.P, Begley, T, Holmgren, A, Case, D.A, Wright, P.E, Dyson, H.J.
登録日1995-11-28
公開日1996-06-10
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献High-resolution solution structures of oxidized and reduced Escherichia coli thioredoxin.
Structure, 2, 1994
1ZNF
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BU of 1znf by Molmil
THREE-DIMENSIONAL SOLUTION STRUCTURE OF A SINGLE ZINC FINGER DNA-BINDING DOMAIN
分子名称: 31ST ZINC FINGER FROM XFIN, ZINC ION
著者Lee, M.S, Gippert, G.P, Soman, K.V, Case, D.A, Wright, P.E.
登録日1989-09-25
公開日1991-07-15
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Three-dimensional solution structure of a single zinc finger DNA-binding domain.
Science, 245, 1989
8W2W
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BU of 8w2w by Molmil
Structure of transthyretin synthetic mutation A120L
分子名称: Transthyretin
著者Yang, K, Sun, X, Ferguson, J.A, Stanfield, R.L, Wright, P.E.
登録日2024-02-21
公開日2024-02-28
最終更新日2024-08-28
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Mispacking of the F87 sidechain drives aggregation-promoting conformational fluctuations in the subunit interfaces of the transthyretin tetramer.
Protein Sci., 33, 2024
8W1N
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BU of 8w1n by Molmil
Structure of transthyretin pathogenic mutation A120S
分子名称: Transthyretin
著者Ferguson, J.A, Stanfield, R.L, Wright, P.E.
登録日2024-02-16
公開日2024-02-28
最終更新日2024-08-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Mispacking of the F87 sidechain drives aggregation-promoting conformational fluctuations in the subunit interfaces of the transthyretin tetramer.
Protein Sci., 33, 2024
1MYF
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BU of 1myf by Molmil
SOLUTION STRUCTURE OF CARBONMONOXY MYOGLOBIN DETERMINED FROM NMR DISTANCE AND CHEMICAL SHIFT CONSTRAINTS
分子名称: CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
著者Osapay, K, Theriault, Y, Wright, P.E, Case, D.A.
登録日1994-12-02
公開日1995-02-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of carbonmonoxy myoglobin determined from nuclear magnetic resonance distance and chemical shift constraints.
J.Mol.Biol., 244, 1994
4NX7
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BU of 4nx7 by Molmil
single cryogenic temperature model of DHFR
分子名称: BETA-MERCAPTOETHANOL, Dihydrofolate reductase, FOLIC ACID, ...
著者Fenwick, R.B, van den Bedem, H, Fraser, J.S, Wright, P.E.
登録日2013-12-08
公開日2014-01-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR.
Proc.Natl.Acad.Sci.USA, 111, 2014
8T5X
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BU of 8t5x by Molmil
Probing the dissociation pathway of a kinetically labile transthyretin mutant (A25T)
分子名称: Transthyretin
著者Ferguson, J.A, Sun, X, Leach, B.I, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2023-06-14
公開日2023-08-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Probing the Dissociation Pathway of a Kinetically Labile Transthyretin Mutant.
J.Am.Chem.Soc., 146, 2024
4NX6
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BU of 4nx6 by Molmil
single room temperature model of DHFR
分子名称: BETA-MERCAPTOETHANOL, Dihydrofolate reductase, FOLIC ACID, ...
著者Fenwick, R.B, van den Bedem, H, Fraser, J.S, Wright, P.E.
登録日2013-12-08
公開日2014-01-15
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR.
Proc.Natl.Acad.Sci.USA, 111, 2014
1TF3
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BU of 1tf3 by Molmil
TFIIIA FINGER 1-3 BOUND TO DNA, NMR, 22 STRUCTURES
分子名称: 5S RNA GENE, TRANSCRIPTION FACTOR IIIA, ZINC ION
著者Foster, M.P, Wuttke, D.S, Radhakrishnan, I, Case, D.A, Gottesfeld, J.M, Wright, P.E.
登録日1997-07-01
公開日1997-09-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA.
Nat.Struct.Biol., 4, 1997
6UNA
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BU of 6una by Molmil
Crystal structure of inactive p38gamma
分子名称: GLYCEROL, Mitogen-activated protein kinase 12, SULFATE ION
著者Aoto, P.C, Stanfield, R.L, Wilson, I.A, Dyson, H.J, Wright, P.E.
登録日2019-10-11
公開日2019-12-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.554 Å)
主引用文献A Dynamic Switch in Inactive p38 gamma Leads to an Excited State on the Pathway to an Active Kinase.
Biochemistry, 58, 2019
6V8U
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BU of 6v8u by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with a modified Kaiso binding sequence (KBS)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*CP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*GP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2019-12-12
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.103 Å)
主引用文献A Conformational Switch in the Zinc Finger Protein Kaiso Mediates Differential Readout of Specific and Methylated DNA Sequences.
Biochemistry, 59, 2020
4F6N
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BU of 4f6n by Molmil
Crystal structure of Kaiso zinc finger DNA binding protein in complex with methylated CpG site DNA
分子名称: DNA (5'-D(*CP*GP*TP*AP*TP*AP*GP*AP*(5CM)P*GP*(5CM)P*GP*GP*TP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*AP*CP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*AP*TP*AP*CP*G)-3'), GLYCEROL, ...
著者Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E.
登録日2012-05-15
公開日2012-09-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012
4F6M
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BU of 4f6m by Molmil
Crystal structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA
分子名称: DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), Transcriptional regulator Kaiso, ...
著者Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E.
登録日2012-05-15
公開日2012-09-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012
4KJK
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BU of 4kjk by Molmil
Room Temperature WT DHFR
分子名称: CALCIUM ION, Dihydrofolate reductase, FOLIC ACID, ...
著者van den Bedem, H, Bhabha, G, Yang, K, Wright, P.E, Fraser, J.S.
登録日2013-05-03
公開日2013-08-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.351 Å)
主引用文献Automated identification of functional dynamic contact networks from X-ray crystallography.
Nat.Methods, 10, 2013
6DFA
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BU of 6dfa by Molmil
Kaiso (ZBTB33) E535A zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2018-05-14
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.908 Å)
主引用文献A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
6DMX
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BU of 6dmx by Molmil
HBZ56 in complex with KIX and c-Myb
分子名称: BZIP factor, CREB-binding protein, Transcriptional activator Myb
著者Yang, K, Wright, P.E, Stanfield, R.L.
登録日2018-06-05
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for cooperative regulation of KIX-mediated transcription pathways by the HTLV-1 HBZ activation domain.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DNQ
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BU of 6dnq by Molmil
HBZ77 in complex with KIX and c-Myb
分子名称: 1,2-ETHANEDIOL, BZIP factor, CREB-binding protein, ...
著者Yang, K, Wright, P.E, Stanfield, R.L.
登録日2018-06-07
公開日2018-09-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis for cooperative regulation of KIX-mediated transcription pathways by the HTLV-1 HBZ activation domain.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DF9
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BU of 6df9 by Molmil
Kaiso (ZBTB33) E535Q zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2018-05-14
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.319 Å)
主引用文献A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
6DF8
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BU of 6df8 by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS), pH 6.5
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2018-05-14
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.536 Å)
主引用文献A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020
6DF5
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BU of 6df5 by Molmil
Kaiso (ZBTB33) zinc finger DNA binding domain in complex with the specific Kaiso binding sequence (KBS)
分子名称: CHLORIDE ION, DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), ...
著者Nikolova, E.N, Stanfield, R.L, Dyson, H.J, Wright, P.E.
登録日2018-05-14
公開日2019-05-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.819 Å)
主引用文献A conformational switch in the zinc finger protein Kaiso mediates differential readout of specific and methylated DNA sequences.
Biochemistry, 2020

 

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