6UNA
Crystal structure of inactive p38gamma
Summary for 6UNA
| Entry DOI | 10.2210/pdb6una/pdb |
| Descriptor | Mitogen-activated protein kinase 12, GLYCEROL, SULFATE ION, ... (4 entities in total) |
| Functional Keywords | mapk, mitogen activated protein kinase, p38 gamma, mapk12, inactive kinase, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 83235.31 |
| Authors | Aoto, P.C.,Stanfield, R.L.,Wilson, I.A.,Dyson, H.J.,Wright, P.E. (deposition date: 2019-10-11, release date: 2019-12-18, Last modification date: 2023-10-11) |
| Primary citation | Aoto, P.C.,Stanfield, R.L.,Wilson, I.A.,Dyson, H.J.,Wright, P.E. A Dynamic Switch in Inactive p38 gamma Leads to an Excited State on the Pathway to an Active Kinase. Biochemistry, 58:5160-5172, 2019 Cited by PubMed: 31794659DOI: 10.1021/acs.biochem.9b00932 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.554 Å) |
Structure validation
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