6UNA

Crystal structure of inactive p38gamma

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000165	biological_process	MAPK cascade
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0004672	molecular_function	protein kinase activity
A	0004674	molecular_function	protein serine/threonine kinase activity
A	0004707	molecular_function	MAP kinase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005829	cellular_component	cytosol
A	0006468	biological_process	protein phosphorylation
A	0007165	biological_process	signal transduction
A	0007517	biological_process	muscle organ development
A	0016301	molecular_function	kinase activity
A	0016504	molecular_function	peptidase activator activity
A	0016740	molecular_function	transferase activity
A	0033554	biological_process	cellular response to stress
A	0035556	biological_process	intracellular signal transduction
A	0042770	biological_process	signal transduction in response to DNA damage
A	0045445	biological_process	myoblast differentiation
A	0045786	biological_process	negative regulation of cell cycle
A	0046872	molecular_function	metal ion binding
A	0051149	biological_process	positive regulation of muscle cell differentiation
A	0051726	biological_process	regulation of cell cycle
A	0106310	molecular_function	protein serine kinase activity
B	0000165	biological_process	MAPK cascade
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0004672	molecular_function	protein kinase activity
B	0004674	molecular_function	protein serine/threonine kinase activity
B	0004707	molecular_function	MAP kinase activity
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005829	cellular_component	cytosol
B	0006468	biological_process	protein phosphorylation
B	0007165	biological_process	signal transduction
B	0007517	biological_process	muscle organ development
B	0016301	molecular_function	kinase activity
B	0016504	molecular_function	peptidase activator activity
B	0016740	molecular_function	transferase activity
B	0033554	biological_process	cellular response to stress
B	0035556	biological_process	intracellular signal transduction
B	0042770	biological_process	signal transduction in response to DNA damage
B	0045445	biological_process	myoblast differentiation
B	0045786	biological_process	negative regulation of cell cycle
B	0046872	molecular_function	metal ion binding
B	0051149	biological_process	positive regulation of muscle cell differentiation
B	0051726	biological_process	regulation of cell cycle
B	0106310	molecular_function	protein serine kinase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue GOL A 401

Chain	Residue
A	GLY126
A	GLU127
A	ASP128
A	ARG129

---

site_id	AC2
Number of Residues	5
Details	binding site for residue SO4 A 402

Chain	Residue
A	LEU119
A	GLU123
A	ASN162
A	CYS165
B	GLU312

---

site_id	AC3
Number of Residues	4
Details	binding site for residue GOL B 401

Chain	Residue
B	GLY126
B	GLU127
B	ASP128
B	ARG129

---

site_id	AC4
Number of Residues	6
Details	binding site for residue SO4 B 402

Chain	Residue
B	LEU119
B	GLU123
B	ARG129
B	ASN162
B	GLU163
B	CYS165

---

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	25
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGSGAYGAVCsAvdgrtgakv.........AIKK

Chain	Residue	Details
A	VAL33-LYS57

---

site_id	PS01351
Number of Residues	104
Details	MAPK MAP kinase signature. FqselfakrayRElrllkhmrhenviglldvftpdetlddftdfylvmpfmgtdlgklmkheklgedriqflvyqmlkglryihaagiih.........RDlKpgnlavnedC

Chain	Residue	Details
A	PHE62-CYS165

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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