NMR structure of CBP TAZ1/CITED2 complex

Summary for 1R8U

DescriptorCbp/p300-interacting transactivator 2, CREB-binding protein, ZINC ION (3 entities in total)
Functional Keywordszinc-binding motifs, protein-protein complex, taz zinc finger, transcription-transcription activator complex, transcription/transcription activator
Biological sourceHomo sapiens (human)
Cellular locationNucleus Q99967
Total number of polymer chains2
Total molecular weight17375.13
De Guzman, R.N.,Martinez-Yamout, M.,Dyson, H.J.,Wright, P.E. (deposition date: 2003-10-28, release date: 2004-03-23, Last modification date: 2011-07-13)
Primary citation
De Guzman, R.N.,Martinez-Yamout, M.A.,Dyson, H.J.,Wright, P.E.
Interaction of the TAZ1 domain of the CREB-binding protein with the activation domain of CITED2: regulation by competition between intrinsically unstructured ligands for non-identical binding sites.
J.Biol.Chem., 279:3042-3049, 2004
PubMed: 14594809 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M310348200
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers01.5%7.7%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation report