9CKV
| Cryo-EM structure of alpha5beta1 integrin in complex with NeoNectin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Werther, R, Nguyen, A, Estrada Alamo, K.A, Wang, X, Campbell, M.G. | 登録日 | 2024-07-09 | 公開日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | 主引用文献 | De Novo Design of Integrin alpha5beta1 Modulating Proteins for Regenerative Medicine To Be Published
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7JTA
| Crystal structure of a putative nuclease with anti-Cas9 activity from an uncultured Clostridia bacterium | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, NITRATE ION, NTF2-like nuclease/anti-CRISPR | 著者 | Werther, R, Forsberg, K.J, Stoddard, B.L. | 登録日 | 2020-08-17 | 公開日 | 2021-09-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | 主引用文献 | The novel anti-CRISPR AcrIIA22 relieves DNA torsion in target plasmids and impairs SpyCas9 activity. Plos Biol., 19, 2021
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5T2O
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5T2H
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5T2N
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6UVW
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6UWK
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6UWJ
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6UWH
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6UWG
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6UW0
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5V0Q
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5T8D
| Engineered variant of I-OnuI meganuclease targeting the HIV integrase gene; harbors 47 point mutations relative to wild-type I-OnuI | 分子名称: | CALCIUM ION, DNA (26-MER), I-OnuI_e-vHIVInt_v2 | 著者 | Stoddard, B.L, Werther, R, Lambert, A.R. | 登録日 | 2016-09-07 | 公開日 | 2017-05-03 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses. Protein Eng.Des.Sel., 30, 2017
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5THG
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8EMC
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8EMH
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8EIL
| C-Terminal Domain of BrxL from Acinetobacter BREX type I phage restriction system | 分子名称: | MALONIC ACID, Protease Lon-related BREX system protein BrxL, SUCCINIC ACID | 著者 | Doyle, L.A, Stoddard, B.L, Kaiser, B. | 登録日 | 2022-09-15 | 公開日 | 2023-02-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure, substrate binding and activity of a unique AAA+ protein: the BrxL phage restriction factor. Nucleic Acids Res., 51, 2023
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