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7L7S
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Human mitochondrial chaperonin mHsp60
分子名称: 60 kDa heat shock protein, mitochondrial
著者Chen, L, Wang, J.C.Y.
登録日2020-12-30
公開日2021-08-25
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis for the structural dynamics of human mitochondrial chaperonin mHsp60.
Sci Rep, 11, 2021
8GCR
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HPV16 E6-E6AP-p53 complex
分子名称: Cellular tumor antigen p53, Maltose/maltodextrin-binding periplasmic protein,Protein E6, Ubiquitin-protein ligase E3A, ...
著者Bratkowski, M.A, Wang, J.C.K, Hao, Q, Nile, A.H.
登録日2023-03-02
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.38 Å)
主引用文献Structure of the p53 degradation complex from HPV16.
Nat Commun, 15, 2024
7TUK
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Small hepatitis B virus surface protein without cytosolic and antigenic loops
分子名称: SAg protein
著者Liu, H, Wang, J.C.Y.
登録日2022-02-02
公開日2022-08-24
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Cryo-EM structures of human hepatitis B and woodchuck hepatitis virus small spherical subviral particles.
Sci Adv, 8, 2022
7TUL
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Woodchuck hepatitis small surface protein without cytosolic and antigenic loops
分子名称: Large envelope protein
著者Liu, H, Wang, J.C.Y.
登録日2022-02-02
公開日2022-08-24
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Cryo-EM structures of human hepatitis B and woodchuck hepatitis virus small spherical subviral particles.
Sci Adv, 8, 2022
8GHS
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Empty HBV Cp183 capsid with importin-beta, subparticle reconstruction at 2-fold location
分子名称: Capsid protein
著者Kim, C, Schlicksup, C.J, Hadden-Perilla, J.A, Wang, J.C.-Y, Zlotnick, A.
登録日2023-03-10
公開日2023-08-09
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure of the Hepatitis B virus capsid quasi-6-fold with a trapped C-terminal domain reveals capsid movements associated with domain exit.
J.Biol.Chem., 299, 2023
6WFS
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Cryo-EM Structure of Hepatitis B virus T=4 capsid in complex with the antiviral molecule DBT1
分子名称: 11-oxo-N-[2-(4-sulfamoylphenyl)ethyl]-10,11-dihydrodibenzo[b,f][1,4]thiazepine-8-carboxamide, Capsid protein
著者Schlicksup, C, Laughlin, P, Dunkelbarger, S, Wang, J.C, Zlotnick, A.
登録日2020-04-03
公開日2020-06-03
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Local Stabilization of Subunit-Subunit Contacts Causes Global Destabilization of Hepatitis B Virus Capsids.
Acs Chem.Biol., 15, 2020
1ECL
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AMINO TERMINAL 67KDA DOMAIN OF ESCHERICHIA COLI DNA TOPOISOMERASE I (RESIDUES 2-590 OF MATURE PROTEIN) CLONING ARTIFACT ADDS TWO RESIDUES TO THE AMINO-TERMINUS WHICH WERE NOT OBSERVED IN THE EXPERIMENTAL ELECTRON DENSITY (GLY-2, SER-1).
分子名称: ESCHERICHIA COLI TOPOISOMERASE I
著者Lima, C.D, Wang, J.C, Mondragon, A.
登録日1995-05-05
公開日1995-07-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Three-dimensional structure of the 67K N-terminal fragment of E. coli DNA topoisomerase I.
Nature, 367, 1994
6EDJ
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Cryo-EM structure of Woodchuck hepatitis virus capsid
分子名称: External core antigen
著者Zhao, Z, Wang, J.C, Zlotnick, A.
登録日2018-08-09
公開日2019-05-01
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.52 Å)
主引用文献Structural Differences between the Woodchuck Hepatitis Virus Core Protein in the Dimer and Capsid States Are Consistent with Entropic and Conformational Regulation of Assembly.
J.Virol., 93, 2019
1OIS
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BU of 1ois by Molmil
YEAST DNA TOPOISOMERASE I, N-TERMINAL FRAGMENT
分子名称: DNA TOPOISOMERASE I
著者Lue, N, Sharma, A, Mondragon, A, Wang, J.C.
登録日1996-09-14
公開日1997-03-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A 26 kDa yeast DNA topoisomerase I fragment: crystallographic structure and mechanistic implications.
Structure, 3, 1995
1BGW
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TOPOISOMERASE RESIDUES 410-1202,
分子名称: TOPOISOMERASE
著者Berger, J.M, Gamblin, S.J, Harrison, S.C, Wang, J.C.
登録日1996-02-20
公開日1996-07-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and mechanism of DNA topoisomerase II.
Nature, 379, 1996
6BVF
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Cryo-EM Structure of Hepatitis B virus T=4 capsid in complex with the fluorescent allosteric modulator HAP-TAMRA
分子名称: Capsid protein, Heteroaryldihydropyrimidine tetramethylrodamine
著者Schlicksup, C, Wang, J.C, Zlotnick, A.
登録日2017-12-12
公開日2018-02-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Hepatitis B virus core protein allosteric modulators can distort and disrupt intact capsids.
Elife, 7, 2018
6BVN
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BU of 6bvn by Molmil
Cryo-EM Structure of Hepatitis B virus T=3 capsid in complex with the fluorescent allosteric modulator HAP-TAMRA
分子名称: Capsid protein, Heteroaryldihydropyrimidine tetramethylrodamine
著者Schlicksup, C, Wang, J.C, Zlotnick, A.
登録日2017-12-13
公開日2018-02-07
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Hepatitis B virus core protein allosteric modulators can distort and disrupt intact capsids.
Elife, 7, 2018
8D8O
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BU of 8d8o by Molmil
Cryo-EM structure of substrate unbound PAPP-A
分子名称: Pappalysin-1, ZINC ION
著者Judge, R.A, Jain, R, Hao, Q, Ouch, C, Sridar, J, Smith, C.L, Wang, J.C.K, Eaton, D.
登録日2022-06-08
公開日2022-09-28
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition
Nat Commun, 13, 2022
7UFG
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Cryo-EM structure of PAPP-A in complex with IGFBP5
分子名称: Insulin-like growth factor-binding protein 5, Pappalysin-1, ZINC ION
著者Judge, R.A, Jain, R, Hao, Q, Ouch, C, Sridar, J, Smith, C.L, Wang, J.C.K, Eaton, D.
登録日2022-03-22
公開日2022-09-28
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献Structure of the PAPP-ABP5 complex reveals mechanism of substrate recognition
Nat Commun, 13, 2022
6LYW
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Structural insight into the biological functions of Arabidopsis thaliana ACHT1
分子名称: GLYCEROL, SULFATE ION, Thioredoxin-like 2-1, ...
著者Wang, J.C, Pan, W.M, Wang, M.Z, Zhang, M.
登録日2020-02-16
公開日2020-05-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural insight into the biological functions of Arabidopsis thaliana ACHT1.
Int.J.Biol.Macromol., 158, 2020
6LYX
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Crystal structure of oxidized ACHT1
分子名称: GLYCEROL, SULFATE ION, Thioredoxin-like 2-1, ...
著者Wang, J.C, Pan, W.M, Cai, W.G, Wang, M.Z, Zhang, M.
登録日2020-02-16
公開日2020-05-13
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.696 Å)
主引用文献Structural insight into the biological functions of Arabidopsis thaliana ACHT1.
Int.J.Biol.Macromol., 158, 2020
6OM2
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Crystal structure of atypical integrin alphaV beta8 with proTGF-beta1 ligand peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Wang, J.C, Springer, T.A.
登録日2019-04-17
公開日2019-12-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献General structural features that regulate integrin affinity revealed by atypical alpha V beta 8.
Nat Commun, 10, 2019
6OM1
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Crystal structure of an atypical integrin
分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Wang, J.C, Springer, T.A.
登録日2019-04-17
公開日2019-12-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献General structural features that regulate integrin affinity revealed by atypical alpha V beta 8.
Nat Commun, 10, 2019
4NS5
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Crystal structure of human BS69 Bromo-Zinc finger-PWWP
分子名称: ZINC ION, Zinc finger MYND domain-containing protein 11
著者Wang, J.C, Qin, S, Li, F.D, Li, S, Zhang, W, Wu, J.H, Shi, Y.Y.
登録日2013-11-28
公開日2014-04-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human BS69 Bromo-ZnF-PWWP reveals its role in H3K36me3 nucleosome binding.
Cell Res., 24, 2014
6VZP
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HBV wild type capsid
分子名称: Capsid protein
著者Zhao, Z, Wang, J, Zlotnick, A.
登録日2020-02-28
公開日2020-09-30
最終更新日2020-12-30
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The Integrity of the Intradimer Interface of the Hepatitis B Virus Capsid Protein Dimer Regulates Capsid Self-Assembly.
Acs Chem.Biol., 15, 2020
6W0K
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HBV D78S mutant capsid
分子名称: Capsid protein
著者Zhao, Z, Wang, J, Zlotnick, A.
登録日2020-03-01
公開日2020-09-30
最終更新日2020-12-30
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献The Integrity of the Intradimer Interface of the Hepatitis B Virus Capsid Protein Dimer Regulates Capsid Self-Assembly.
Acs Chem.Biol., 15, 2020
8URQ
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Spo11 core complex with gapped DNA
分子名称: Antiviral protein SKI8, MAGNESIUM ION, Meiosis-specific protein SPO11, ...
著者Yu, Y, Patel, D.J.
登録日2023-10-26
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structure of the yeast Spo11 core complex bound to DNA
To Be Published
8URU
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Spo11 core complex with hairpin DNA
分子名称: Antiviral protein SKI8, Hairpin DNA, MAGNESIUM ION, ...
著者Yu, Y, Patel, D.J.
登録日2023-10-26
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of the yeast Spo11 core complex bound to DNA
To Be Published
6JEA
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crystal structure of a beta-N-acetylhexosaminidase
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-N-acetylhexosaminidase, ZINC ION
著者Chen, X, Wang, J.C, Liu, M.J, Yang, W.Y, Wang, Y.Z, Tang, R.P, Zhang, M.
登録日2019-02-04
公開日2019-03-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.275 Å)
主引用文献Crystallographic evidence for substrate-assisted catalysis of beta-N-acetylhexosaminidas from Akkermansia muciniphila.
Biochem. Biophys. Res. Commun., 511, 2019
6JE8
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crystal structure of a beta-N-acetylhexosaminidase
分子名称: Beta-N-acetylhexosaminidase, FORMIC ACID, GLYCEROL, ...
著者Chen, X, Wang, J.C, Liu, M.J, Yang, W.Y, Wang, Y.Z, Tang, R.P, Zhang, M.
登録日2019-02-04
公開日2019-03-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.798 Å)
主引用文献Crystallographic evidence for substrate-assisted catalysis of beta-N-acetylhexosaminidas from Akkermansia muciniphila.
Biochem. Biophys. Res. Commun., 511, 2019

 

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