2IDK
 
 | | Crystal Structure of Rat Glycine N-Methyltransferase Complexed With Folate | | 分子名称: | 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, Glycine N-methyltransferase | | 著者 | Luka, Z, Pakhomova, S, Loukachevitch, L.V, Egli, M, Newcomer, M.E, Wagner, C. | | 登録日 | 2006-09-15 | | 公開日 | 2006-12-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | 5-methyltetrahydrofolate is bound in intersubunit areas of rat liver folate-binding protein glycine N-methyltransferase.
J.Biol.Chem., 282, 2007
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2IDJ
 | | Crystal Structure of Rat Glycine N-Methyltransferase Apoprotein, Monoclinic Form | | 分子名称: | CALCIUM ION, Glycine N-methyltransferase | | 著者 | Luka, Z, Pakhomova, S, Loukachevitch, L.V, Egli, M, Newcomer, M.E, Wagner, C. | | 登録日 | 2006-09-15 | | 公開日 | 2006-12-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | 5-methyltetrahydrofolate is bound in intersubunit areas of rat liver folate-binding protein glycine N-methyltransferase.
J.Biol.Chem., 282, 2007
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2YN3
 | | Structural insight into the giant calcium-binding adhesin SiiE: implications for the adhesion of Salmonella enterica to polarized epithelial cells | | 分子名称: | CALCIUM ION, IODIDE ION, PHOSPHATE ION, ... | | 著者 | Griessl, M.H, Schmid, B, Kassler, K, Braunsmann, C, Ritter, R, Barlag, B, Sturm, K.U, Danzer, C, Wagner, C, Schaeffer, T.E, Sticht, H, Hensel, M, Muller, Y.A. | | 登録日 | 2012-10-11 | | 公開日 | 2013-04-03 | | 最終更新日 | 2013-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Structural Insight Into the Giant Ca(2+)-Binding Adhesin Siie: Implications for the Adhesion of Salmonella Enterica to Polarized Epithelial Cells.
Structure, 21, 2013
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2YN5
 | | Structural insight into the giant calcium-binding adhesin SiiE: implications for the adhesion of Salmonella enterica to polarized epithelial cells | | 分子名称: | CALCIUM ION, PUTATIVE INNER MEMBRANE PROTEIN | | 著者 | Griessl, M.H, Schmid, B, Kassler, K, Braunsmann, C, Ritter, R, Barlag, B, Sturm, K.U, Danzer, C, Wagner, C, Schaeffer, T.E, Sticht, H, Hensel, M, Muller, Y.A. | | 登録日 | 2012-10-12 | | 公開日 | 2013-04-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural Insight Into the Giant Ca(2+)-Binding Adhesin Siie: Implications for the Adhesion of Salmonella Enterica to Polarized Epithelial Cells.
Structure, 21, 2013
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4S1D
 | | Structure of IgG1 Fab fragment in complex with Biotincytidinamide | | 分子名称: | MAB M33 FAB FRAGMENT, heavy chain, light chain, ... | | 著者 | Dengl, S, Hoffmann, E, Grote, M, Wagner, C, Mundigl, O, Georges, G, Theorey, I, Stubenrauch, K.-G, Bujotzek, A, Josel, H.-P, Dziadek, S, Benz, J, Brinkmann, U. | | 登録日 | 2015-01-13 | | 公開日 | 2015-03-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Hapten-directed spontaneous disulfide shuffling: a universal technology for site-directed covalent coupling of payloads to antibodies.
Faseb J., 29, 2015
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4PAA
 | | Crystal structure of the mature form of rat DMGDH complexed with tetrahydrofolate | | 分子名称: | (6S)-5,6,7,8-TETRAHYDROFOLATE, Dimethylglycine dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Luka, Z, Pakhomova, S, Loukachevitch, L.V, Newcomer, M.E, Wagner, C. | | 登録日 | 2014-04-07 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Folate in demethylation: The crystal structure of the rat dimethylglycine dehydrogenase complexed with tetrahydrofolate.
Biochem.Biophys.Res.Commun., 449, 2014
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4PAB
 | | Crystal structure of the precursor form of rat DMGDH complexed with tetrahydrofolate | | 分子名称: | (6S)-5,6,7,8-TETRAHYDROFOLATE, Dimethylglycine dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Luka, Z, Pakhomova, S, Loukachevitch, L.V, Newcomer, M.E, Wagner, C. | | 登録日 | 2014-04-07 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Folate in demethylation: The crystal structure of the rat dimethylglycine dehydrogenase complexed with tetrahydrofolate.
Biochem.Biophys.Res.Commun., 449, 2014
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4P9S
 | | Crystal structure of the mature form of rat DMGDH | | 分子名称: | Dimethylglycine dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Luka, Z, Pakhomova, S, Loukachevitch, L.V, Newcomer, M.E, Wagner, C. | | 登録日 | 2014-04-04 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Folate in demethylation: The crystal structure of the rat dimethylglycine dehydrogenase complexed with tetrahydrofolate.
Biochem.Biophys.Res.Commun., 449, 2014
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4KUM
 | | Structure of LSD1-CoREST-Tetrahydrofolate complex | | 分子名称: | (6S)-5,6,7,8-TETRAHYDROFOLATE, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Luka, Z, Pakhomova, S, Loukachevitch, L.V, Calcutt, M.W, Newcomer, M.E, Wagner, C. | | 登録日 | 2013-05-22 | | 公開日 | 2014-05-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Crystal structure of the histone lysine specific demethylase LSD1 complexed with tetrahydrofolate.
Protein Sci., 23, 2014
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4LID
 | | A100, A DNA binding scaffold from Sulfolobus spindle-shape virus 1 | | 分子名称: | A-100 | | 著者 | Eilers, B.J, Wagner, C, Thomas, M.M, Lawrence, C.M, Young, M.J. | | 登録日 | 2013-07-02 | | 公開日 | 2014-09-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | A100, A DNA binding scaffold from Sulfolobus spindle-shape virus 1
To be Published
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3THS
 | | Crystal structure of rat native liver Glycine N-methyltransferase complexed with 5-methyltetrahydrofolate pentaglutamate | | 分子名称: | 5-methyltetrahydrofolate pentaglutamate, BETA-MERCAPTOETHANOL, Glycine N-methyltransferase, ... | | 著者 | Luka, Z, Pakhomova, S, Loukachevitch, L.V, Newcomer, M.E, Wagner, C. | | 登録日 | 2011-08-19 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Differences in folate-protein interactions result in differing inhibition of native rat liver and recombinant glycine N-methyltransferase by 5-methyltetrahydrofolate.
Biochim.Biophys.Acta, 1824, 2011
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3THR
 | | Crystal structure of rat native liver Glycine N-methyltransferase complexed with 5-methyltetrahydrofolate monoglutamate | | 分子名称: | 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, Glycine N-methyltransferase, TRIS(HYDROXYETHYL)AMINOMETHANE | | 著者 | Luka, Z, Pakhomova, S, Loukachevitch, L.V, Newcomer, M.E, Wagner, C. | | 登録日 | 2011-08-19 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Differences in folate-protein interactions result in differing inhibition of native rat liver and recombinant glycine N-methyltransferase by 5-methyltetrahydrofolate.
Biochim.Biophys.Acta, 1824, 2011
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2AZT
 | | Crystal structure of H176N mutant of human Glycine N-Methyltransferase | | 分子名称: | BETA-MERCAPTOETHANOL, CHLORIDE ION, CITRIC ACID, ... | | 著者 | Luka, Z, Pakhomova, S, Luka, Y, Newcomer, M.E, Wagner, C. | | 登録日 | 2005-09-12 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Destabilization of human glycine N-methyltransferase by H176N mutation.
Protein Sci., 16, 2007
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1R8Y
 | | Crystal Structure of Mouse Glycine N-Methyltransferase (Monoclinic Form) | | 分子名称: | BETA-MERCAPTOETHANOL, glycine N-methyltransferase | | 著者 | Pakhomova, S, Luka, Z, Wagner, C, Newcomer, M.E. | | 登録日 | 2003-10-28 | | 公開日 | 2004-09-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.
Proteins, 57, 2004
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1R74
 | | Crystal Structure of Human Glycine N-Methyltransferase | | 分子名称: | BETA-MERCAPTOETHANOL, CITRIC ACID, Glycine N-methyltransferase | | 著者 | Pakhomova, S, Luka, Z, Wagner, C, Newcomer, M.E. | | 登録日 | 2003-10-17 | | 公開日 | 2004-09-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.
Proteins, 57, 2004
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1R8X
 | | Crystal Structure of Mouse Glycine N-Methyltransferase (Tetragonal Form) | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-MERCAPTOETHANOL, glycine N-methyltransferase | | 著者 | Pakhomova, S, Luka, Z, Wagner, C, Newcomer, M.E. | | 登録日 | 2003-10-28 | | 公開日 | 2004-09-21 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Glycine N-methyltransferases: a comparison of the crystal structures and kinetic properties of recombinant human, mouse and rat enzymes.
Proteins, 57, 2004
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1BHJ
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7U4C
 | | Borrelia burgdorferi HtpG N-terminal domain (1-228) in complex with BX-2819 | | 分子名称: | Chaperone protein HtpG, ethyl (4-{3-[2,4-dihydroxy-5-(1-methylethyl)phenyl]-5-sulfanyl-4H-1,2,4-triazol-4-yl}benzyl)carbamate | | 著者 | Kowalewski, M.E, Lietzan, A, Haystead, T, Redinbo, M.R. | | 登録日 | 2022-02-28 | | 公開日 | 2023-03-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Targeting Borrelia burgdorferi HtpG with a berserker molecule, a strategy for anti-microbial development.
Cell Chem Biol, 2023
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3ZNS
 | | HDAC7 bound with TFMO inhibitor tmp942 | | 分子名称: | HISTONE DEACETYLASE 7, N-{[1-methyl-4-(4-phenyl-1,3-thiazol-2-yl)piperidin-4-yl]methyl}-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, POTASSIUM ION, ... | | 著者 | Lobera, M, Madauss, K.P, Pohlhaus, D.T, Trump, R.P, Nolan, M.A. | | 登録日 | 2013-02-15 | | 公開日 | 2013-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Selective Class Iia Histone Deacetylase Inhibition Via a Non-Chelating Zinc Binding Group
Nat.Chem.Biol., 9, 2013
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3ZNR
 | | HDAC7 bound with inhibitor TMP269 | | 分子名称: | HISTONE DEACETYLASE 7, N-{[4-(4-phenyl-1,3-thiazol-2-yl)tetrahydro-2H-pyran-4-yl]methyl}-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide, POTASSIUM ION, ... | | 著者 | Lobera, m, madauss, k, pohlhaus, d, trump, r, nolan, m. | | 登録日 | 2013-02-15 | | 公開日 | 2013-03-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Selective Class Iia Histone Deacetylase Inhibition Via a Non-Chelating Zinc Binding Group
Nat.Chem.Biol., 9, 2013
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6NT2
 | | type 1 PRMT in complex with the inhibitor GSK3368715 | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, N~1~-({5-[4,4-bis(ethoxymethyl)cyclohexyl]-1H-pyrazol-4-yl}methyl)-N~1~,N~2~-dimethylethane-1,2-diamine, ... | | 著者 | Concha, N.O. | | 登録日 | 2019-01-28 | | 公開日 | 2019-07-10 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss.
Cancer Cell, 36, 2019
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6E9V
 | | DHF79 filament | | 分子名称: | DHF79 filament | | 著者 | Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D. | | 登録日 | 2018-08-01 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | | 主引用文献 | De novo design of self-assembling helical protein filaments.
Science, 362, 2018
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6E9Y
 | | DHF38 filament | | 分子名称: | DHF38 filament | | 著者 | Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D. | | 登録日 | 2018-08-01 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | De novo design of self-assembling helical protein filaments.
Science, 362, 2018
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6E9X
 | | DHF91 filament | | 分子名称: | DHF91 filament | | 著者 | Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D. | | 登録日 | 2018-08-01 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | | 主引用文献 | De novo design of self-assembling helical protein filaments.
Science, 362, 2018
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6E9Z
 | | DHF119 filament | | 分子名称: | DHF119 filament | | 著者 | Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D. | | 登録日 | 2018-08-01 | | 公開日 | 2018-11-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | De novo design of self-assembling helical protein filaments.
Science, 362, 2018
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