4S1D

Structure of IgG1 Fab fragment in complex with Biotincytidinamide

Summary for 4S1D

• Entry DOI: 10.2210/pdb4s1d/pdb
• Descriptor: MAB M33 FAB FRAGMENT, heavy chain, MAB M33 FAB FRAGMENT, light chain, N~6~-{5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoyl}-L-lysinamide, ... (5 entities in total)
• Functional Keywords: antibody, fab fragment, hapten, mab_m33_fab_fragment, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 8
• Total formula weight: 191160.23

Authors

Dengl, S.,Hoffmann, E.,Grote, M.,Wagner, C.,Mundigl, O.,Georges, G.,Theorey, I.,Stubenrauch, K.-G.,Bujotzek, A.,Josel, H.-P.,Dziadek, S.,Benz, J.,Brinkmann, U. (deposition date: 2015-01-13, release date: 2015-03-04, Last modification date: 2024-04-03)

• Primary citation: Dengl, S.,Hoffmann, E.,Grote, M.,Wagner, C.,Mundigl, O.,Georges, G.,Thorey, I.,Stubenrauch, K.G.,Bujotzek, A.,Josel, H.P.,Dziadek, S.,Benz, J.,Brinkmann, U.; Hapten-directed spontaneous disulfide shuffling: a universal technology for site-directed covalent coupling of payloads to antibodies.; Faseb J., 29:1763-1779, 2015; PubMed: 25670234; DOI: 10.1096/fj.14-263665

Experimental method

X-RAY DIFFRACTION (2.5 Å)