2AZT

Crystal structure of H176N mutant of human Glycine N-Methyltransferase

Summary for 2AZT

• Entry DOI: 10.2210/pdb2azt/pdb
• Related: 1R74
• Descriptor: Glycine N-methyltransferase, BETA-MERCAPTOETHANOL, CITRIC ACID, ... (5 entities in total)
• Functional Keywords: glycine n-methyltransferase, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q14749
• Total number of polymer chains: 2
• Total formula weight: 66330.79

Authors

Luka, Z.,Pakhomova, S.,Luka, Y.,Newcomer, M.E.,Wagner, C. (deposition date: 2005-09-12, release date: 2006-09-26, Last modification date: 2023-08-23)

• Primary citation: Luka, Z.,Pakhomova, S.,Luka, Y.,Newcomer, M.E.,Wagner, C.; Destabilization of human glycine N-methyltransferase by H176N mutation.; Protein Sci., 16:1957-1964, 2007; PubMed: 17660255; DOI: 10.1110/ps.072921507

Experimental method

X-RAY DIFFRACTION (2.7 Å)