7Z3P
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![BU of 7z3p by Molmil](/molmil-images/mine/7z3p) | Crystal structure of the mouse leptin:LepR-CRH2 encounter complex to 1.95 A resolution. | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, Leptin, ... | 著者 | Tsirigotaki, A, Verschueren, K, Savvides, S.N, Verstraete, K. | 登録日 | 2022-03-02 | 公開日 | 2023-03-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.943 Å) | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
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7Z3R
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![BU of 7z3r by Molmil](/molmil-images/mine/7z3r) | Crystal structure of the mouse leptin:LepR-IgCRH2 complex to 2.95 A resolution. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor | 著者 | Verstraete, K, Verschueren, K, Savvides, S.N, Tsirigotaki, A. | 登録日 | 2022-03-02 | 公開日 | 2023-03-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.951 Å) | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
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8AV2
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![BU of 8av2 by Molmil](/molmil-images/mine/8av2) | Crystal structure for the FnIII module of mouse LEP-R in complex with the anti-LEP-R nanobody VHH-4.80 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin receptor, SULFATE ION, ... | 著者 | Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. | 登録日 | 2022-08-26 | 公開日 | 2023-04-05 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
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8AVC
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![BU of 8avc by Molmil](/molmil-images/mine/8avc) | Mouse leptin:LEP-R complex cryoEM structure (3:3 model) | 分子名称: | Leptin, Leptin receptor, NICKEL (II) ION | 著者 | Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. | 登録日 | 2022-08-26 | 公開日 | 2023-04-05 | 最終更新日 | 2023-04-26 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
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8AVD
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![BU of 8avd by Molmil](/molmil-images/mine/8avd) | Cryo-EM structure for a 3:3 complex between mouse leptin and the mouse LEP-R ectodomain (local refinement) | 分子名称: | Leptin, Leptin receptor, NICKEL (II) ION | 著者 | Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. | 登録日 | 2022-08-26 | 公開日 | 2023-04-05 | 最終更新日 | 2023-04-26 | 実験手法 | ELECTRON MICROSCOPY (4.42 Å) | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
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8AVO
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![BU of 8avo by Molmil](/molmil-images/mine/8avo) | Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (open 3:3 model). | 分子名称: | Leptin, Leptin receptor | 著者 | Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. | 登録日 | 2022-08-26 | 公開日 | 2023-04-05 | 最終更新日 | 2023-04-26 | 実験手法 | ELECTRON MICROSCOPY (6.84 Å) | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
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8AVE
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![BU of 8ave by Molmil](/molmil-images/mine/8ave) | Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (2:2 model) | 分子名称: | Leptin, Leptin receptor | 著者 | Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. | 登録日 | 2022-08-26 | 公開日 | 2023-04-05 | 最終更新日 | 2023-04-26 | 実験手法 | ELECTRON MICROSCOPY (5.62 Å) | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
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8AVF
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![BU of 8avf by Molmil](/molmil-images/mine/8avf) | Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (closed 3:3 model) | 分子名称: | Leptin, Leptin receptor | 著者 | Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. | 登録日 | 2022-08-26 | 公開日 | 2023-04-05 | 最終更新日 | 2023-04-26 | 実験手法 | ELECTRON MICROSCOPY (6.45 Å) | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
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8AVB
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![BU of 8avb by Molmil](/molmil-images/mine/8avb) | Cryo-EM structure for mouse leptin in complex with the mouse LEP-R ectodomain (1:2 mLEP:mLEPR model). | 分子名称: | Leptin, Leptin receptor | 著者 | Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. | 登録日 | 2022-08-26 | 公開日 | 2023-04-05 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (4.43 Å) | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
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8B7Q
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![BU of 8b7q by Molmil](/molmil-images/mine/8b7q) | Cryo-EM structure for the mouse LEPR-CRH2:Leptin:LEPR-Ig complex following symmetry expansion in combination with local refinement | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor | 著者 | Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A. | 登録日 | 2022-09-30 | 公開日 | 2023-04-05 | 最終更新日 | 2023-04-26 | 実験手法 | ELECTRON MICROSCOPY (4.02 Å) | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
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7Z3Q
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![BU of 7z3q by Molmil](/molmil-images/mine/7z3q) | Crystal structure of the human leptin:LepR-CRH2 encounter complex to 3.6 A resolution. | 分子名称: | Leptin, Leptin receptor | 著者 | Verstraete, K, Verschueren, K, Alexandra, T, Savvides, S.N. | 登録日 | 2022-03-02 | 公開日 | 2023-03-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.617 Å) | 主引用文献 | Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023
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