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7Z3P
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BU of 7z3p by Molmil
Crystal structure of the mouse leptin:LepR-CRH2 encounter complex to 1.95 A resolution.
分子名称: CALCIUM ION, DI(HYDROXYETHYL)ETHER, Leptin, ...
著者Tsirigotaki, A, Verschueren, K, Savvides, S.N, Verstraete, K.
登録日2022-03-02
公開日2023-03-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.943 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
7Z3R
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BU of 7z3r by Molmil
Crystal structure of the mouse leptin:LepR-IgCRH2 complex to 2.95 A resolution.
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor
著者Verstraete, K, Verschueren, K, Savvides, S.N, Tsirigotaki, A.
登録日2022-03-02
公開日2023-03-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.951 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
8AV2
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BU of 8av2 by Molmil
Crystal structure for the FnIII module of mouse LEP-R in complex with the anti-LEP-R nanobody VHH-4.80
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin receptor, SULFATE ION, ...
著者Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
登録日2022-08-26
公開日2023-04-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
8AVC
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BU of 8avc by Molmil
Mouse leptin:LEP-R complex cryoEM structure (3:3 model)
分子名称: Leptin, Leptin receptor, NICKEL (II) ION
著者Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
登録日2022-08-26
公開日2023-04-05
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
8AVD
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BU of 8avd by Molmil
Cryo-EM structure for a 3:3 complex between mouse leptin and the mouse LEP-R ectodomain (local refinement)
分子名称: Leptin, Leptin receptor, NICKEL (II) ION
著者Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
登録日2022-08-26
公開日2023-04-05
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (4.42 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
8AVO
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BU of 8avo by Molmil
Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (open 3:3 model).
分子名称: Leptin, Leptin receptor
著者Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
登録日2022-08-26
公開日2023-04-05
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (6.84 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
8AVE
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BU of 8ave by Molmil
Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (2:2 model)
分子名称: Leptin, Leptin receptor
著者Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
登録日2022-08-26
公開日2023-04-05
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (5.62 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
8AVF
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BU of 8avf by Molmil
Human leptin in complex with the human LEP-R ectodomain fused to a C-terminal trimeric isoleucine GCN4 zipper (closed 3:3 model)
分子名称: Leptin, Leptin receptor
著者Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
登録日2022-08-26
公開日2023-04-05
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (6.45 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
8AVB
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BU of 8avb by Molmil
Cryo-EM structure for mouse leptin in complex with the mouse LEP-R ectodomain (1:2 mLEP:mLEPR model).
分子名称: Leptin, Leptin receptor
著者Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
登録日2022-08-26
公開日2023-04-05
最終更新日2023-07-26
実験手法ELECTRON MICROSCOPY (4.43 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
8B7Q
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BU of 8b7q by Molmil
Cryo-EM structure for the mouse LEPR-CRH2:Leptin:LEPR-Ig complex following symmetry expansion in combination with local refinement
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor
著者Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
登録日2022-09-30
公開日2023-04-05
最終更新日2023-04-26
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023
7Z3Q
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BU of 7z3q by Molmil
Crystal structure of the human leptin:LepR-CRH2 encounter complex to 3.6 A resolution.
分子名称: Leptin, Leptin receptor
著者Verstraete, K, Verschueren, K, Alexandra, T, Savvides, S.N.
登録日2022-03-02
公開日2023-03-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.617 Å)
主引用文献Mechanism of receptor assembly via the pleiotropic adipokine Leptin.
Nat.Struct.Mol.Biol., 30, 2023

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件を2024-06-12に公開中

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