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1RQF
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BU of 1rqf by Molmil
Structure of CK2 beta subunit crystallized in the presence of a p21WAF1 peptide
分子名称: Casein kinase II beta chain, Disordered segment of Cyclin-dependent kinase inhibitor 1, UNKNOWN, ...
著者Bertrand, L, Sayed, M.F, Pei, X.-Y, Parisini, E, Dhanaraj, V, Bolanos-Garcia, V.M, Allende, J.E, Blundell, T.L.
登録日2003-12-05
公開日2004-10-05
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Structure of the regulatory subunit of CK2 in the presence of a p21WAF1 peptide demonstrates flexibility of the acidic loop.
Acta Crystallogr.,Sect.D, 60, 2004
8VEJ
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BU of 8vej by Molmil
De novo designed cholic acid binder: CHD_buttress
分子名称: CHD_buttress, CHOLIC ACID
著者Bera, A.K, Tran, L, Kang, A, Baker, D.
登録日2023-12-19
公開日2024-07-17
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (3.59 Å)
主引用文献Binding and sensing diverse small molecules using shape-complementary pseudocycles.
Science, 385, 2024
5M1W
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BU of 5m1w by Molmil
Structure of a stable G-hairpin
分子名称: DNA (5'-D(*GP*TP*GP*TP*GP*GP*GP*TP*GP*TP*G)-3')
著者Gajarsky, M, Zivkovic, M.L, Stadlbauer, P, Pagano, B, Fiala, R, Amato, J, Tomaska, L, Sponer, J, Plavec, J, Trantirek, L.
登録日2016-10-11
公開日2017-03-01
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of a Stable G-Hairpin.
J. Am. Chem. Soc., 139, 2017
6R8E
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BU of 6r8e by Molmil
SC14 G-hairpin
分子名称: DNA (5'-D(*GP*TP*GP*TP*GP*TP*GP*GP*GP*TP*GP*TP*GP*T)-3')
著者Lenarcic Zivkovic, M, Trantirek, L, Plavec, J.
登録日2019-04-01
公開日2021-02-03
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Insight into formation propensity of pseudocircular DNA G-hairpins.
Nucleic Acids Res., 49, 2021
8BZU
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BU of 8bzu by Molmil
Double-ion dependent DNA quadruplex structure formed by C.elegans telomeric sequence
分子名称: DNA (5'-D(*GP*GP*CP*TP*TP*AP*GP*GP*CP*TP*TP*AP*GP*GP*CP*TP*TP*AP*GP*GP*C)-3')
著者Lenarcic Zivkovic, M, Trantirek, L.
登録日2022-12-15
公開日2024-03-13
実験手法SOLUTION NMR
主引用文献DNA Quadruplex Structure with a Unique Cation Dependency.
Angew.Chem.Int.Ed.Engl., 63, 2024
2M21
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BU of 2m21 by Molmil
Solution structure of the Tetrahymena telomerase RNA stem IV terminal loop
分子名称: 5'-R(*GP*GP*CP*GP*AP*UP*AP*CP*AP*CP*UP*AP*UP*UP*UP*AP*UP*CP*GP*CP*C)-3'
著者Cash, D.D, Richards, R.J, Wu, H, Trantirek, L, O'Connor, C.M, Feigon, J, Collins, K.
登録日2012-12-11
公開日2013-03-20
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural study of elements of Tetrahymena telomerase RNA stem-loop IV domain important for function.
Rna, 12, 2006
2YLY
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BU of 2yly by Molmil
Sulfonamides as selective Estrogen Receptor beta Agonists.
分子名称: ESTROGEN RECEPTOR BETA, N-cyclopropyl-4-oxidanyl-N-[(2R)-2-oxidanyl-2-phenyl-propyl]benzenesulfonamide, SULFATE ION
著者Roberts, L.R, Armour, D, Barker, C, Bazin, R, Bess, K, Brown, A, Favor, D, Ellis, D, MacKenny, M, Pullen, N, Stennett, A, Strand, L, Styles, M, Phillips, C.
登録日2011-06-06
公開日2012-06-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Sulfonamides as Selective Oestrogen Receptor Beta Agonists.
Bioorg.Med.Chem.Lett., 21, 2011
2GID
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BU of 2gid by Molmil
Crystal structures of trypanosoma bruciei MRP1/MRP2
分子名称: mitochondrial RNA-binding protein 1, mitochondrial RNA-binding protein 2
著者Schumacher, M.A, Karamooz, E, Zikova, A, Trantirek, L, Lukes, J.
登録日2006-03-28
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Crystal Structures of T. brucei MRP1/MRP2 Guide-RNA Binding Complex Reveal RNA Matchmaking Mechanism.
Cell(Cambridge,Mass.), 126, 2006
2GIA
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BU of 2gia by Molmil
Crystal structures of trypanosoma bruciei MRP1/MRP2
分子名称: ACETIC ACID, mitochondrial RNA-binding protein 1, mitochondrial RNA-binding protein 2
著者Schumacher, M.A, Karamooz, E, Zikova, A, Trantirek, L, Lukes, J.
登録日2006-03-28
公開日2006-09-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal Structures of T. brucei MRP1/MRP2 Guide-RNA Binding Complex Reveal RNA Matchmaking Mechanism.
Cell(Cambridge,Mass.), 126, 2006
2GJE
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BU of 2gje by Molmil
Structure of a guideRNA-binding protein complex bound to a gRNA
分子名称: RNA tetramer, guide RNA 40-mer, mitochondrial RNA-binding protein 1, ...
著者Schumacher, M.A, Karamooz, E, Zikova, A, Trantirek, L, Lukes, J.
登録日2006-03-30
公開日2006-09-05
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.37 Å)
主引用文献Crystal Structures of T. brucei MRP1/MRP2 Guide-RNA Binding Complex Reveal RNA Matchmaking Mechanism.
Cell(Cambridge,Mass.), 126, 2006
1NA2
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BU of 1na2 by Molmil
Solution structure of the p2b hairpin from human telomerase RNA
分子名称: telomerase RNA p2b hairpin
著者Theimer, C.A, Finger, L.D, Trantirek, L, Feigon, J.
登録日2002-11-26
公開日2003-01-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA
Proc.Natl.Acad.Sci.USA, 100, 2003
1QWB
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BU of 1qwb by Molmil
NMR structure of 5'-r(GGACACGAAAUCCCGAAGUAGUGUCC)-3' : an RNA hairpin containing the in vitro selected consensus sequence for nucleolin RBD12
分子名称: sNRE26
著者Finger, L.D, Trantirek, L, Johansson, C, Feigon, J.
登録日2003-09-01
公開日2003-11-25
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution Structures of Stem-loop RNAs that Bind the Two N-terminal RNA-binding Domains of Nucleolin
Nucleic Acids Res., 31, 2003
1QWA
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BU of 1qwa by Molmil
NMR structure of 5'-r(GGAUGCCUCCCGAGUGCAUCC): an RNA hairpin derived from the mouse 5'ETS that binds nucleolin RBD12.
分子名称: 18S ribosomal RNA, 5'ETS
著者Finger, L.D, Trantirek, L, Johansson, C, Feigon, J.
登録日2003-09-01
公開日2003-11-25
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution Strucutres of Stem-loop RNAs that Bind to the Two N-terminal RNA Binding Domains of Nucleolin
Nucleic Acids Res., 31, 2003
1RKJ
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BU of 1rkj by Molmil
Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target
分子名称: 5'-R(*GP*GP*AP*UP*GP*CP*CP*UP*CP*CP*CP*GP*AP*GP*UP*GP*CP*AP*UP*CP*C)-3', Nucleolin
著者Johansson, C, Finger, L.D, Trantirek, L, Mueller, T.D, Kim, S, Laird-Offringa, I.A, Feigon, J.
登録日2003-11-21
公開日2004-04-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target.
J.Mol.Biol., 337, 2004
4YDJ
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BU of 4ydj by Molmil
Crystal structure of broadly and potently neutralizing antibody 44-VRC13.01 in complex with HIV-1 clade AE strain 93TH057 gp120
分子名称: (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Zhou, T, Moquin, S, Kwong, P.D.
登録日2015-02-22
公開日2015-06-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.308 Å)
主引用文献Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
4YDL
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BU of 4ydl by Molmil
Crystal structure of broadly and potently neutralizing antibody C38-VRC18.02 in complex with HIV-1 clade AE strain 93TH057gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Envelope glycoprotein gp160,Envelope glycoprotein gp160, ...
著者Zhou, T, Srivatsan, S, Kwong, P.D.
登録日2015-02-22
公開日2015-06-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
4YFL
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BU of 4yfl by Molmil
Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 1B2530 in complex with HIV-1 clade A/E 93TH057 gp120
分子名称: 1B2530 Light chain, 1B2530 heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Acharya, P, Zhou, T, Moquin, S, Kwong, P.D.
登録日2015-02-25
公開日2015-06-03
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.387 Å)
主引用文献Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
4YDI
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BU of 4ydi by Molmil
Crystal structure of broad and potently neutralizing VRC01-class antibody Z258-VRC27.01, isolated from human donor Z258, in complex with HIV-1 gp120 from clade A strain Q23.17
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
著者Zhou, T, Srivatsan, S, Kwong, P.D.
登録日2015-02-22
公開日2015-06-03
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.452 Å)
主引用文献Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
4YDK
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BU of 4ydk by Molmil
Crystal structure of broadly and potently neutralizing antibody C38-VRC16.01 in complex with HIV-1 clade AE strain 93TH057 gp120
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Zhou, T, Moquin, S, Zheng, A, Kwong, P.D.
登録日2015-02-22
公開日2015-06-03
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.051 Å)
主引用文献Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
4YE4
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BU of 4ye4 by Molmil
Crystal Structure of Neutralizing Antibody HJ16 in Complex with HIV-1 gp120
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HT593.1 gp120, Heavy chain human antibody HJ16, ...
著者Kwong, P.D, Chen, L, Zhou, T.
登録日2015-02-23
公開日2015-07-22
最終更新日2022-03-30
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell, 161, 2015
8VEI
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BU of 8vei by Molmil
De novo designed colic acid binder CHD_r1
分子名称: CHD_r1
著者Bera, A.K, An, L, Baker, D.
登録日2023-12-19
公開日2024-07-17
最終更新日2024-07-31
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Binding and sensing diverse small molecules using shape-complementary pseudocycles.
Science, 385, 2024
8EQF
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BU of 8eqf by Molmil
cryoEM structure of a broadly neutralizing anti-SARS-CoV-2 antibody STI-9167
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ...
著者Bajic, G.
登録日2022-10-07
公開日2023-10-11
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献An in vitro experimental pipeline to characterize the epitope of a SARS-CoV-2 neutralizing antibody.
Mbio, 15, 2024
4RX4
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BU of 4rx4 by Molmil
Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC134 in complex with HIV-1 clade A Q842.d12 gp120
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC134 Heavy chain, ...
著者Zhou, T, Acharya, P, Moquin, S, Kwong, P.D.
登録日2014-12-08
公開日2015-07-01
最終更新日2021-06-02
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell(Cambridge,Mass.), 161, 2015
4RWY
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BU of 4rwy by Molmil
Crystal structure of VH1-46 germline-derived CD4-binding site-directed antibody 8ANC131 in complex with HIV-1 clade B YU2 gp120
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
著者Acharya, P, Luongo, T.S, Kwong, P.D.
登録日2014-12-08
公開日2015-07-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.128 Å)
主引用文献Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Cell(Cambridge,Mass.), 161, 2015
5I2C
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BU of 5i2c by Molmil
Arginine-bound CASTOR1 from Homo sapiens
分子名称: ACETATE ION, ARGININE, GATS-like protein 3
著者Saxton, R.A, Knockenhauer, K.E, Schwartz, T.U.
登録日2016-02-08
公開日2016-08-10
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.801 Å)
主引用文献Mechanism of arginine sensing by CASTOR1 upstream of mTORC1.
Nature, 536, 2016

 

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