8VEJ

De novo designed cholic acid binder: CHD_buttress

Summary for 8VEJ

• Entry DOI: 10.2210/pdb8vej/pdb
• Descriptor: CHD_buttress, CHOLIC ACID (2 entities in total)
• Functional Keywords: de novo designed protein, cholic acid, small molecule binder, de novo protein
• Biological source: synthetic construct
• Total number of polymer chains: 2
• Total formula weight: 55766.08

Authors

Bera, A.K.,Tran, L.,Kang, A.,Baker, D. (deposition date: 2023-12-19, release date: 2024-07-17, Last modification date: 2024-07-31)

• Primary citation: An, L.,Said, M.,Tran, L.,Majumder, S.,Goreshnik, I.,Lee, G.R.,Juergens, D.,Dauparas, J.,Anishchenko, I.,Coventry, B.,Bera, A.K.,Kang, A.,Levine, P.M.,Alvarez, V.,Pillai, A.,Norn, C.,Feldman, D.,Zorine, D.,Hicks, D.R.,Li, X.,Sanchez, M.G.,Vafeados, D.K.,Salveson, P.J.,Vorobieva, A.A.,Baker, D.; Binding and sensing diverse small molecules using shape-complementary pseudocycles.; Science, 385:276-282, 2024; PubMed: 39024436; DOI: 10.1126/science.adn3780

Experimental method