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4DKE
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BU of 4dke by Molmil
Crystal Structure of Human Interleukin-34 Bound to FAb1.1
分子名称: FAb1.1 Heavy Chain, FAb1.1 Light Chain, Interleukin-34, ...
著者Ma, X, Chen, Y, Stawicki, S, Wu, Y, Bazan, J.F, Starovasnik, M.A.
登録日2012-02-03
公開日2012-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
4DKF
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BU of 4dkf by Molmil
Crystal Structure of Human Interleukin-34 Bound to FAb2
分子名称: FAb2 Heavy Chain, FAb2 Light Chain, Interleukin-34, ...
著者Ma, X, Chen, Y, Stawicki, S, Wu, Y, Bazan, J.F, Starovasnik, M.A.
登録日2012-02-03
公開日2012-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
3GRW
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BU of 3grw by Molmil
FGFR3 in complex with a Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ...
著者Wiesmann, C.
登録日2009-03-26
公開日2009-05-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice.
J.Clin.Invest., 119, 2009
3L95
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BU of 3l95 by Molmil
Crystal structure of the human Notch1 Negative Regulatory Region (NRR) bound to the fab fragment of an antagonist antibody
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neurogenic locus notch homolog protein 1, ...
著者Hymowitz, S.G, de Leon, G.P.
登録日2010-01-04
公開日2010-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Therapeutic antibody targeting of individual Notch receptors.
Nature, 464, 2010
3P0Y
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BU of 3p0y by Molmil
anti-EGFR/HER3 Fab DL11 in complex with domain III of EGFR extracellular region
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
著者Eigenbrot, C, Shia, S.
登録日2010-09-29
公開日2011-10-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.
Cancer Cell, 20, 2011
3P0V
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BU of 3p0v by Molmil
anti-EGFR/HER3 Fab DL11 alone
分子名称: CALCIUM ION, Fab DL11 heavy chain, Fab DL11 light chain
著者Eigenbrot, C, Shia, S.
登録日2010-09-29
公開日2011-10-19
最終更新日2012-03-21
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.
Cancer Cell, 20, 2011
3P11
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BU of 3p11 by Molmil
anti-EGFR/HER3 Fab DL11 in complex with domains I-III of the HER3 extracellular region
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab DL11 heavy chain, ...
著者Eigenbrot, C, Shia, S.
登録日2010-09-29
公開日2011-10-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies.
Cancer Cell, 20, 2011
3G6J
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BU of 3g6j by Molmil
C3b in complex with a C3b specific Fab
分子名称: CALCIUM ION, Complement C3 alpha chain, Complement C3 beta chain, ...
著者Wiesmann, C.
登録日2009-02-06
公開日2009-03-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of Complement
J.Biol.Chem., 284, 2009
4DKC
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BU of 4dkc by Molmil
Crystal Structure of Human Interleukin-34
分子名称: Interleukin-34, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Ma, X, Bazan, J.F, Starovasnik, M.A.
登録日2012-02-03
公開日2012-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
4DKD
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BU of 4dkd by Molmil
Crystal Structure of Human Interleukin-34 Bound to Human CSF-1R
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-34, ...
著者Ma, X, Bazan, J.F, Starovasnik, M.A.
登録日2012-02-03
公開日2012-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
2R0L
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BU of 2r0l by Molmil
Short Form HGFA with Inhibitory Fab75
分子名称: Hepatocyte growth factor activator, antibody heavy chain, Fab portion only, ...
著者Eigenbrot, C, Shia, S.
登録日2007-08-20
公開日2007-12-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural insight into distinct mechanisms of protease inhibition by antibodies.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2R0K
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BU of 2r0k by Molmil
Protease domain of HGFA with inhibitor Fab58
分子名称: Hepatocyte growth factor activator, antibody heavy chain of Fab58, Fab portion only, ...
著者Eigenbrot, C, Shia, S.
登録日2007-08-20
公開日2007-12-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.51 Å)
主引用文献Structural insight into distinct mechanisms of protease inhibition by antibodies.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2QQO
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BU of 2qqo by Molmil
Crystal Structure of the a2b1b2 Domains from Human Neuropilin-2
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ...
著者Appleton, B.A, Wiesmann, C.
登録日2007-07-26
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26, 2007
2QQM
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BU of 2qqm by Molmil
Crystal Structure of the a2b1b2 Domains from Human Neuropilin-1
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Appleton, B.A, Wiesmann, C.
登録日2007-07-26
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26, 2007
2QQN
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BU of 2qqn by Molmil
Neuropilin-1 b1 Domain in Complex with a VEGF-Blocking Fab
分子名称: 1,2-ETHANEDIOL, Antibody heavy chain, Antibody light chain, ...
著者Appleton, B.A, Wiesmann, C.
登録日2007-07-26
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26, 2007
2QQK
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BU of 2qqk by Molmil
Neuropilin-2 a1a2b1b2 Domains in Complex with a Semaphorin-Blocking Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Heavy Chain, Antibody Light Chain, ...
著者Appleton, B.A, Wiesmann, C.
登録日2007-07-26
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26, 2007
2QQI
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BU of 2qqi by Molmil
Crystal Structure of the b1b2 Domains from Human Neuropilin-1
分子名称: GLYCEROL, Neuropilin-1
著者Appleton, B.A, Desmarais, W, Wiesmann, C.
登録日2007-07-26
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26, 2007
2QQL
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BU of 2qql by Molmil
Neuropilin-2 a1a2b1b2 Domains in Complex with a Semaphorin-Blocking Fab
分子名称: Antibody Heavy Chain, Antibody Light Chain, Neuropilin-2
著者Appleton, B.A, Wiesmann, C.
登録日2007-07-26
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26, 2007
2QQJ
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BU of 2qqj by Molmil
Crystal Structure of the b1b2 Domains from Human Neuropilin-2
分子名称: GLYCEROL, Neuropilin-2
著者Appleton, B.A, Wiesmann, C.
登録日2007-07-26
公開日2007-11-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26, 2007

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