4DKE
| Crystal Structure of Human Interleukin-34 Bound to FAb1.1 | 分子名称: | FAb1.1 Heavy Chain, FAb1.1 Light Chain, Interleukin-34, ... | 著者 | Ma, X, Chen, Y, Stawicki, S, Wu, Y, Bazan, J.F, Starovasnik, M.A. | 登録日 | 2012-02-03 | 公開日 | 2012-04-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R. Structure, 20, 2012
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4DKF
| Crystal Structure of Human Interleukin-34 Bound to FAb2 | 分子名称: | FAb2 Heavy Chain, FAb2 Light Chain, Interleukin-34, ... | 著者 | Ma, X, Chen, Y, Stawicki, S, Wu, Y, Bazan, J.F, Starovasnik, M.A. | 登録日 | 2012-02-03 | 公開日 | 2012-04-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R. Structure, 20, 2012
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3GRW
| FGFR3 in complex with a Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... | 著者 | Wiesmann, C. | 登録日 | 2009-03-26 | 公開日 | 2009-05-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice. J.Clin.Invest., 119, 2009
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3L95
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3P0Y
| anti-EGFR/HER3 Fab DL11 in complex with domain III of EGFR extracellular region | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ... | 著者 | Eigenbrot, C, Shia, S. | 登録日 | 2010-09-29 | 公開日 | 2011-10-26 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies. Cancer Cell, 20, 2011
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3P0V
| anti-EGFR/HER3 Fab DL11 alone | 分子名称: | CALCIUM ION, Fab DL11 heavy chain, Fab DL11 light chain | 著者 | Eigenbrot, C, Shia, S. | 登録日 | 2010-09-29 | 公開日 | 2011-10-19 | 最終更新日 | 2012-03-21 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | A two-in-one antibody against HER3 and EGFR has superior inhibitory activity compared with monospecific antibodies. Cancer Cell, 20, 2011
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3P11
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3G6J
| C3b in complex with a C3b specific Fab | 分子名称: | CALCIUM ION, Complement C3 alpha chain, Complement C3 beta chain, ... | 著者 | Wiesmann, C. | 登録日 | 2009-02-06 | 公開日 | 2009-03-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural and Functional Analysis of a C3b-specific Antibody That Selectively Inhibits the Alternative Pathway of Complement J.Biol.Chem., 284, 2009
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4DKC
| Crystal Structure of Human Interleukin-34 | 分子名称: | Interleukin-34, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Ma, X, Bazan, J.F, Starovasnik, M.A. | 登録日 | 2012-02-03 | 公開日 | 2012-04-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R. Structure, 20, 2012
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4DKD
| Crystal Structure of Human Interleukin-34 Bound to Human CSF-1R | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-34, ... | 著者 | Ma, X, Bazan, J.F, Starovasnik, M.A. | 登録日 | 2012-02-03 | 公開日 | 2012-04-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R. Structure, 20, 2012
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2R0L
| Short Form HGFA with Inhibitory Fab75 | 分子名称: | Hepatocyte growth factor activator, antibody heavy chain, Fab portion only, ... | 著者 | Eigenbrot, C, Shia, S. | 登録日 | 2007-08-20 | 公開日 | 2007-12-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural insight into distinct mechanisms of protease inhibition by antibodies. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2R0K
| Protease domain of HGFA with inhibitor Fab58 | 分子名称: | Hepatocyte growth factor activator, antibody heavy chain of Fab58, Fab portion only, ... | 著者 | Eigenbrot, C, Shia, S. | 登録日 | 2007-08-20 | 公開日 | 2007-12-25 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.51 Å) | 主引用文献 | Structural insight into distinct mechanisms of protease inhibition by antibodies. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2QQO
| Crystal Structure of the a2b1b2 Domains from Human Neuropilin-2 | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... | 著者 | Appleton, B.A, Wiesmann, C. | 登録日 | 2007-07-26 | 公開日 | 2007-11-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding Embo J., 26, 2007
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2QQM
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2QQN
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2QQK
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2QQI
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2QQL
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2QQJ
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