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2QQI

Crystal Structure of the b1b2 Domains from Human Neuropilin-1

Summary for 2QQI
Entry DOI10.2210/pdb2qqi/pdb
Related2QQJ 2QQK 2QQL 2QQM 2QQN 2QQO
DescriptorNeuropilin-1, GLYCEROL (3 entities in total)
Functional Keywordsvegf receptor, semaphorin receptor, angiogenesis, developmental protein, differentiation, glycoprotein, heparan sulfate, membrane, neurogenesis, proteoglycan, secreted, transmembrane, hormone, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: O14786
Total number of polymer chains1
Total formula weight36171.02
Authors
Appleton, B.A.,Desmarais, W.,Wiesmann, C. (deposition date: 2007-07-26, release date: 2007-11-20, Last modification date: 2023-08-30)
Primary citationAppleton, B.A.,Wu, P.,Maloney, J.,Yin, J.,Liang, W.C.,Stawicki, S.,Mortara, K.,Bowman, K.K.,Elliott, J.M.,Desmarais, W.,Bazan, J.F.,Bagri, A.,Tessier-Lavigne, M.,Koch, A.W.,Wu, Y.,Watts, R.J.,Wiesmann, C.
Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding
Embo J., 26:4902-4912, 2007
Cited by
PubMed: 17989695
DOI: 10.1038/sj.emboj.7601906
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

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