6NQ1
 
 | | Cryo-EM structure of human TPC2 channel in the apo state | | 分子名称: | Two pore calcium channel protein 2 | | 著者 | She, J, Zeng, W, Guo, J, Chen, Q, Bai, X, Jiang, Y. | | 登録日 | 2019-01-18 | | 公開日 | 2019-03-27 | | 最終更新日 | 2019-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural mechanisms of phospholipid activation of the human TPC2 channel.
Elife, 8, 2019
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6NQ0
 | | Cryo-EM structure of human TPC2 channel in the ligand-bound open state | | 分子名称: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Two pore calcium channel protein 2 | | 著者 | She, J, Zeng, W, Guo, J, Chen, Q, Bai, X, Jiang, Y. | | 登録日 | 2019-01-18 | | 公開日 | 2019-03-27 | | 最終更新日 | 2019-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural mechanisms of phospholipid activation of the human TPC2 channel.
Elife, 8, 2019
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6C9A
 | | Cryo-EM structure of mouse TPC1 channel in the PtdIns(3,5)P2-bound state | | 分子名称: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | She, J, Guo, J, Chen, Q, Bai, X, Jiang, Y. | | 登録日 | 2018-01-25 | | 公開日 | 2018-04-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into the voltage and phospholipid activation of the mammalian TPC1 channel.
Nature, 556, 2018
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6C96
 | | Cryo-EM structure of mouse TPC1 channel in the apo state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SODIUM ION, ... | | 著者 | She, J, Guo, J, Chen, Q, Bai, X, Jiang, Y. | | 登録日 | 2018-01-25 | | 公開日 | 2018-04-04 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural insights into the voltage and phospholipid activation of the mammalian TPC1 channel.
Nature, 556, 2018
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8IOW
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8J6F
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6NQ2
 | | Cryo-EM structure of human TPC2 channel in the ligand-bound closed state | | 分子名称: | (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,4,6-trihydroxy-3,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dioctanoate, Two pore calcium channel protein 2 | | 著者 | She, J, Zeng, W, Guo, J, Chen, Q, Bai, X, Jiang, Y. | | 登録日 | 2019-01-18 | | 公開日 | 2019-03-27 | | 最終更新日 | 2019-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural mechanisms of phospholipid activation of the human TPC2 channel.
Elife, 8, 2019
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5JJD
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6WF2
 | | Crystal structure of mouse SCD1 with a diiron center | | 分子名称: | Acyl-CoA desaturase 1, FE (III) ION, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name) | | 著者 | Shen, J, Zhou, M. | | 登録日 | 2020-04-03 | | 公開日 | 2020-06-17 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.51 Å) | | 主引用文献 | Structure and Mechanism of a Unique Diiron Center in Mammalian Stearoyl-CoA Desaturase.
J.Mol.Biol., 432, 2020
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8HZ5
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8HZ4
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8G3G
 | | CryoEM structure of yeast recombination mediator Rad52 | | 分子名称: | DNA repair and recombination protein RAD52 | | 著者 | Deveryshetty, J, Basore, K, Rau, M, Fitzpatrick, J.A.J, Antony, E. | | 登録日 | 2023-02-07 | | 公開日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Yeast Rad52 is a homodecamer and possesses BRCA2-like bipartite Rad51 binding modes.
Nat Commun, 14, 2023
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7S8U
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8DL6
 | | Cryo-EM structure of human ferroportin/slc40 bound to Ca2+ in nanodisc | | 分子名称: | 11F9 heavy-chain, 11F9 light-chain, CALCIUM ION, ... | | 著者 | Shen, J, Wilbon, A.S, Pan, Y, Zhou, M. | | 登録日 | 2022-07-07 | | 公開日 | 2023-01-25 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mechanism of Ca 2+ transport by ferroportin.
Elife, 12, 2023
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4U38
 | | RNA duplex containing UU mispair | | 分子名称: | RNA (5'-R(*GP*GP*UP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*UP*CP*C)-3') | | 著者 | Sheng, J, Larsen, A, Heuberger, B, Blain, J.C, Szostak, J.W. | | 登録日 | 2014-07-18 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs.
J.Am.Chem.Soc., 136, 2014
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4U34
 | | Crystal Structures of RNA Duplexes Containing 2-thio-Uridine | | 分子名称: | RNA (5'-R(*GP*GP*AP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*(SUR)P*CP*C-3') | | 著者 | Sheng, J, Larsen, A, Heuberger, B, Blain, J.C, Szostak, J.W. | | 登録日 | 2014-07-18 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs.
J.Am.Chem.Soc., 136, 2014
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4U35
 | | Crystal Structures of RNA Duplexes Containing 2-thio-Uridine | | 分子名称: | RNA (5'-R(*GP*GP*UP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*(SUR)P*CP*C-3') | | 著者 | Sheng, J, Larsen, A, Heuberger, B, Blain, J.C, Szostak, J.W. | | 登録日 | 2014-07-18 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs.
J.Am.Chem.Soc., 136, 2014
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4U37
 | | Native 7mer-RNA duplex | | 分子名称: | RNA (5'-R(*GP*GP*AP*GP*CP*UP*A)-3'), RNA (5'-R(*UP*AP*GP*CP*UP*CP*C)-3') | | 著者 | Sheng, J, Larsen, A, Heuberger, B, Blain, J.C, Szostak, J.W. | | 登録日 | 2014-07-18 | | 公開日 | 2014-08-13 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal Structure Studies of RNA Duplexes Containing s(2)U:A and s(2)U:U Base Pairs.
J.Am.Chem.Soc., 136, 2014
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5H7P
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4MSB
 | | RNA 10mer duplex with two 2'-5'-linkages | | 分子名称: | RNA 10mer duplex with two 2'-5'-linkages, STRONTIUM ION | | 著者 | Sheng, J, Li, L, Engelhart, A.E, Gan, J, Wang, J, Szostak, J.W. | | 登録日 | 2013-09-18 | | 公開日 | 2014-02-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural insights into the effects of 2'-5' linkages on the RNA duplex.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4MSR
 | | RNA 10mer duplex with six 2'-5'-linkages | | 分子名称: | RNA 10mer duplex with six 2'-5'-linkages, STRONTIUM ION | | 著者 | Sheng, J, Li, L, Engelhart, A.E, Gan, J, Wang, J, Szostak, J.W. | | 登録日 | 2013-09-18 | | 公開日 | 2014-02-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structural insights into the effects of 2'-5' linkages on the RNA duplex.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4MS9
 | | Native RNA-10mer Structure: ccggcgccgg | | 分子名称: | Native RNA duplex 10mer, STRONTIUM ION | | 著者 | Sheng, J, Li, L, Engelhart, A.E, Gan, J, Wang, J, Szostak, J.W. | | 登録日 | 2013-09-18 | | 公開日 | 2014-02-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | Structural insights into the effects of 2'-5' linkages on the RNA duplex.
Proc.Natl.Acad.Sci.USA, 111, 2014
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7F6H
 | | Cryo-EM structure of human bradykinin receptor BK2R in complex Gq proteins and bradykinin | | 分子名称: | Bradykinin, Bradykinin receptor BK2R, CHOLESTEROL, ... | | 著者 | Shen, J, Zhang, D, Fu, Y, Chen, A, Zhang, H. | | 登録日 | 2021-06-25 | | 公開日 | 2022-01-05 | | 最終更新日 | 2023-01-18 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Cryo-EM structures of human bradykinin receptor-G q proteins complexes.
Nat Commun, 13, 2022
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7F6I
 | | Cryo-EM structure of human bradykinin receptor BK2R in complex Gq proteins and kallidin | | 分子名称: | Bradykinin receptor BK2R, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Shen, J, Zhang, D, Fu, Y, Chen, A, Zhang, H. | | 登録日 | 2021-06-25 | | 公開日 | 2022-01-05 | | 最終更新日 | 2023-01-18 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures of human bradykinin receptor-G q proteins complexes.
Nat Commun, 13, 2022
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5E36
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