2GIF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2gif by Molmil](/molmil-images/mine/2gif) | Asymmetric structure of trimeric AcrB from Escherichia coli | 分子名称: | Acriflavine resistance protein B, CITRATE ANION | 著者 | Seeger, M.A, Schiefner, A, Eicher, T, Verrey, F, Diederichs, K, Pos, K.M. | 登録日 | 2006-03-28 | 公開日 | 2006-09-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism. Science, 313, 2006
|
|
2HRT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2hrt by Molmil](/molmil-images/mine/2hrt) | Asymmetric structure of trimeric AcrB from Escherichia coli | 分子名称: | Acriflavine resistance protein B, CITRATE ANION | 著者 | Seeger, M.A, Schiefner, A, Eicher, T, Verrey, F, Diederichs, K, Pos, K.M. | 登録日 | 2006-07-20 | 公開日 | 2006-09-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism. Science, 313, 2006
|
|
4J7W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4j7w by Molmil](/molmil-images/mine/4j7w) | E3_5 DARPin L86A mutant | 分子名称: | DARPin_E3_5_L86A | 著者 | Seeger, M.A, Gruetter, M.G. | 登録日 | 2013-02-14 | 公開日 | 2013-08-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Design, construction, and characterization of a second-generation DARPin library with reduced hydrophobicity. Protein Sci., 22, 2013
|
|
4J8Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4j8y by Molmil](/molmil-images/mine/4j8y) | E3_5 DARPin D77S mutant | 分子名称: | DARPin_E3_5_D77S | 著者 | Seeger, M.A, Gruetter, M.G. | 登録日 | 2013-02-15 | 公開日 | 2013-08-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Design, construction, and characterization of a second-generation DARPin library with reduced hydrophobicity. Protein Sci., 22, 2013
|
|
4JB8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4jb8 by Molmil](/molmil-images/mine/4jb8) | Caspase-7 in Complex with DARPin C7_16 | 分子名称: | Caspase-7 subunit p11, Caspase-7 subunit p20, DARPin C7_16 | 著者 | Fluetsch, A, Seeger, M.A, Gruetter, M.G. | 登録日 | 2013-02-19 | 公開日 | 2013-08-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Design, construction, and characterization of a second-generation DARPin library with reduced hydrophobicity. Protein Sci., 22, 2013
|
|
4Q7K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4q7k by Molmil](/molmil-images/mine/4q7k) | |
4Q7L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4q7l by Molmil](/molmil-images/mine/4q7l) | Structure of NBD288 of TM287/288 | 分子名称: | NICKEL (II) ION, Uncharacterized ABC transporter ATP-binding protein TM_0288 | 著者 | Bukowska, M.A, Hohl, M, Gruetter, M.G, Seeger, M.A. | 登録日 | 2014-04-25 | 公開日 | 2015-05-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | A Transporter Motor Taken Apart: Flexibility in the Nucleotide Binding Domains of a Heterodimeric ABC Exporter. Biochemistry, 54, 2015
|
|
4Q7M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4q7m by Molmil](/molmil-images/mine/4q7m) | |
4Q4A
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4q4a by Molmil](/molmil-images/mine/4q4a) | Improved model of AMP-PNP bound TM287/288 | 分子名称: | ABC transporter, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Hohl, M, Gruetter, M.G, Seeger, M.A. | 登録日 | 2014-04-14 | 公開日 | 2014-07-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4Q4J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4q4j by Molmil](/molmil-images/mine/4q4j) | Structure of crosslinked TM287/288_S498C_S520C mutant | 分子名称: | ABC transporter, Uncharacterized ABC transporter ATP-binding protein TM_0288 | 著者 | Hohl, M, Schoeppe, J, Gruetter, M.G, Seeger, M.A. | 登録日 | 2014-04-14 | 公開日 | 2014-07-16 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4Q4H
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4q4h by Molmil](/molmil-images/mine/4q4h) | TM287/288 in its apo state | 分子名称: | ABC transporter, Uncharacterized ABC transporter ATP-binding protein TM_0288 | 著者 | Hohl, M, Gruetter, M.G, Seeger, M.A. | 登録日 | 2014-04-14 | 公開日 | 2014-07-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.527 Å) | 主引用文献 | Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
6ZBV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zbv by Molmil](/molmil-images/mine/6zbv) | Inward-open structure of human glycine transporter 1 in complex with a benzoylisoindoline inhibitor and sybody Sb_GlyT1#7 | 分子名称: | Sodium- and chloride-dependent glycine transporter 1,Sodium- and chloride-dependent glycine transporter 1, Sybody Sb_GlyT1#7, [5-fluoranyl-6-(oxan-4-yloxy)-1,3-dihydroisoindol-2-yl]-[5-methylsulfonyl-2-[2,2,3,3,3-pentakis(fluoranyl)propoxy]phenyl]methanone | 著者 | Shahsavar, A, Stohler, P, Bourenkov, G, Zimmermann, I, Siegrist, M, Guba, W, Pinard, E, Sinning, S, Seeger, M.A, Schneider, T.R, Dawson, R.J.P, Nissen, P. | 登録日 | 2020-06-09 | 公開日 | 2021-03-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural insights into the inhibition of glycine reuptake. Nature, 591, 2021
|
|
9FZC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9fzc by Molmil](/molmil-images/mine/9fzc) | |
9FZD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 9fzd by Molmil](/molmil-images/mine/9fzd) | |
6OEI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oei by Molmil](/molmil-images/mine/6oei) | Yeast Spc42 N-terminal coiled-coil fused to PDB: 3K2N | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Spindle pole body component SPC42,Sigma-54-dependent transcriptional regulator | 著者 | Drennan, A.C, Krishna, S, Seeger, M.A, Andreas, M.P, Gardner, J.M, Sether, E.K.R, Jaspersen, S.L, Rayment, I. | 登録日 | 2019-03-27 | 公開日 | 2019-04-24 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Structure and function of Spc42 coiled-coils in yeast centrosome assembly and duplication. Mol.Biol.Cell, 30, 2019
|
|
6OEC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oec by Molmil](/molmil-images/mine/6oec) | Yeast Spc42 Trimeric Coiled-Coil Amino Acids 181-211 fused to PDB: 3H5I | 分子名称: | CALCIUM ION, Response regulator/sensory box protein/GGDEF domain protein,Spindle pole body component SPC42 | 著者 | Drennan, A.C, Shivaani, K, Seeger, M.A, Andreas, M.P, Gardner, J.M, Sether, E.K.R, Jasperson, S.L, Rayment, I. | 登録日 | 2019-03-27 | 公開日 | 2019-04-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.514 Å) | 主引用文献 | Structure and function of Spc42 coiled-coils in yeast centrosome assembly and duplication. Mol.Biol.Cell, 30, 2019
|
|
8PNL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8pnl by Molmil](/molmil-images/mine/8pnl) | Outward-open conformation of a Major Facilitator Superfamily (MFS) transporter MHAS2168, a homologue of Rv1410 from M. tuberculosis, in complex with an alpaca nanobody | 分子名称: | Nb_H2, Putative triacylglyceride transporter | 著者 | Remm, S, Schoeppe, J, Hutter, C.A.J, Gonda, I, Seeger, M.A. | 登録日 | 2023-06-30 | 公開日 | 2023-10-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for triacylglyceride extraction from mycobacterial inner membrane by MFS transporter Rv1410. Nat Commun, 14, 2023
|
|
6OD2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6od2 by Molmil](/molmil-images/mine/6od2) | Yeast Spc42 C-terminal Antiparallel Coiled-Coil | 分子名称: | Spindle pole body component SPC42 | 著者 | Drennan, A.C, Krishna, S, Seeger, M.A, Andreas, M.P, Gardner, J.M, Sether, E.K.R, Jaspersen, S.L, Rayment, I. | 登録日 | 2019-03-25 | 公開日 | 2019-04-24 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2.435 Å) | 主引用文献 | Structure and function of Spc42 coiled-coils in yeast centrosome assembly and duplication. Mol.Biol.Cell, 30, 2019
|
|
6SY9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6sy9 by Molmil](/molmil-images/mine/6sy9) | Structure of the Legionella pneumophila response regulator LqsR | 分子名称: | Response regulator | 著者 | Hochstrasser, R, Hutter, C.A.J, Arnold, F.M, Baerlocher, K, Seeger, M.A, Hilbi, H. | 登録日 | 2019-09-27 | 公開日 | 2020-02-05 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The structure of the Legionella response regulator LqsR reveals amino acids critical for phosphorylation and dimerization. Mol.Microbiol., 113, 2020
|
|
6TEJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tej by Molmil](/molmil-images/mine/6tej) | Structure of apo IrtAB devoid SID in complex with sybody Syb_NL5 | 分子名称: | DECYL-BETA-D-MALTOPYRANOSIDE, Drug ABC transporter ATP-binding protein, NICKEL (II) ION, ... | 著者 | Gonda, I, Arnold, F.M, Hutter, C.A.J, Weber, M.S, Seeger, M.A, Hurlimann, L.M. | 登録日 | 2019-11-12 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The ABC exporter IrtAB imports and reduces mycobacterial siderophores. Nature, 580, 2020
|
|
6TEK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tek by Molmil](/molmil-images/mine/6tek) | Structure of siderophore interaction domain of IrtAB | 分子名称: | Drug ABC transporter ATP-binding protein, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Arnold, F.M, Gonda, I, Hutter, C.A.J, Seeger, M.A, Hurlimann, L.M. | 登録日 | 2019-11-12 | 公開日 | 2020-04-01 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The ABC exporter IrtAB imports and reduces mycobacterial siderophores. Nature, 580, 2020
|
|
7PH3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ph3 by Molmil](/molmil-images/mine/7ph3) | AMP-PNP bound nanodisc reconstituted MsbA with nanobodies, spin-labeled at position A60C | 分子名称: | (1~{R},4~{R},11~{S},14~{S},19~{Z})-19-[2-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]ethylimino]-7,8,17,18-tetraoxa-1,4,11,14-tetrazatricyclo[12.6.2.2^{4,11}]tetracosane-6,9,16-trione, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ATP-dependent lipid A-core flippase, ... | 著者 | Parey, K, Januliene, D, Galazzo, L, Meier, G, Vecchis, D, Striednig, B, Hilbi, H, Schaefer, L.V, Kuprov, I, Bordignon, E, Seeger, M.A, Moeller, A. | 登録日 | 2021-08-16 | 公開日 | 2022-08-24 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells. Sci Adv, 8, 2022
|
|
7PH7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ph7 by Molmil](/molmil-images/mine/7ph7) | Nanodisc reconstituted MsbA in complex with nanobodies, spin-labeled at position T68C | 分子名称: | (1~{R},4~{R},11~{S},14~{S},19~{Z})-19-[2-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]ethylimino]-7,8,17,18-tetraoxa-1,4,11,14-tetrazatricyclo[12.6.2.2^{4,11}]tetracosane-6,9,16-trione, (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{S},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3,5-bis(oxidanyl)oxan-2-yl]oxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-4-[(3~{R})-3-nonanoyloxytetradecanoyl]oxy-5-[[(3~{R})-3-octanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{S},5~{S},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanylnonanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-oxan-2-yl]methoxy]-5-oxidanyl-oxane-2-carboxylic acid, ATP-binding transport protein multicopy suppressor of htrB, ... | 著者 | Parey, K, Januliene, D, Galazzo, L, Meier, G, Vecchis, D, Striednig, B, Hilbi, H, Schaefer, L.V, Kuprov, I, Bordignon, E, Seeger, M.A, Moeller, A. | 登録日 | 2021-08-16 | 公開日 | 2022-08-24 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells. Sci Adv, 8, 2022
|
|
7PH2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ph2 by Molmil](/molmil-images/mine/7ph2) | Nanodisc reconstituted MsbA in complex with nanobodies, spin-labeled at position A60C | 分子名称: | (1~{R},4~{R},11~{S},14~{S},19~{Z})-19-[2-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]ethylimino]-7,8,17,18-tetraoxa-1,4,11,14-tetrazatricyclo[12.6.2.2^{4,11}]tetracosane-6,9,16-trione, (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{S},5~{R},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-4-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3,5-bis(oxidanyl)oxan-2-yl]oxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-4-[(3~{R})-3-nonanoyloxytetradecanoyl]oxy-5-[[(3~{R})-3-octanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{S},5~{S},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanylnonanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-oxan-2-yl]methoxy]-5-oxidanyl-oxane-2-carboxylic acid, ATP-dependent lipid A-core flippase, ... | 著者 | Januliene, D, Parey, K, Galazzo, L, Meier, G, Vecchis, D, Striednig, B, Hilbi, H, Schaefer, L.V, Kuprov, I, Bordignon, E, Seeger, M.A, Moeller, A. | 登録日 | 2021-08-16 | 公開日 | 2022-08-24 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells. Sci Adv, 8, 2022
|
|
7PH4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ph4 by Molmil](/molmil-images/mine/7ph4) | AMP-PNP bound nanodisc reconstituted MsbA with nanobodies, spin-labeled at position T68C | 分子名称: | (1~{R},4~{R},11~{S},14~{S},19~{Z})-19-[2-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]ethylimino]-7,8,17,18-tetraoxa-1,4,11,14-tetrazatricyclo[12.6.2.2^{4,11}]tetracosane-6,9,16-trione, ATP-dependent lipid A-core flippase, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Parey, K, Januliene, D, Galazzo, L, Meier, G, Vecchis, D, Striednig, B, Hilbi, H, Schaefer, L.V, Kuprov, I, Bordignon, E, Seeger, M.A, Moeller, A. | 登録日 | 2021-08-16 | 公開日 | 2022-08-24 | 最終更新日 | 2022-10-26 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells. Sci Adv, 8, 2022
|
|