1HKL
 
 | | FREE AND LIGANDED FORM OF AN ESTEROLYTIC CATALYTIC ANTIBODY | | 分子名称: | 48G7 FAB | | 著者 | Wedemayer, G.J, Wang, L.H, Patten, P.A, Schultz, P.G, Stevens, R.C. | | 登録日 | 1996-12-20 | | 公開日 | 1997-03-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Crystal structures of the free and liganded form of an esterolytic catalytic antibody.
J.Mol.Biol., 268, 1997
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2AG6
 | | Crystal structure of p-bromo-l-phenylalanine-tRNA sythetase in complex with p-bromo-l-phenylalanine | | 分子名称: | 4-BROMO-L-PHENYLALANINE, Tyrosyl-tRNA synthetase | | 著者 | Turner, J.M, Graziano, J, Spraggon, G, Schultz, P.G. | | 登録日 | 2005-07-26 | | 公開日 | 2006-04-04 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural plasticity of an aminoacyl-tRNA synthetase active site
Proc.Natl.Acad.Sci.Usa, 103, 2006
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2RCS
 | | IMMUNOGLOBULIN 48G7 GERMLINE FAB-AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY | | 分子名称: | IMMUNOGLOBULIN 48G7 GERMLINE FAB | | 著者 | Wedemayer, G.J, Wang, L.H, Patten, P.A, Schultz, P.G, Stevens, R.C. | | 登録日 | 1997-05-14 | | 公開日 | 1997-11-12 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural insights into the evolution of an antibody combining site.
Science, 276, 1997
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2PW8
 | | Crystal structure of sulfo-hirudin complexed to thrombin | | 分子名称: | Hirudin variant-1, NICKEL (II) ION, SODIUM ION, ... | | 著者 | Liu, C.C, Brustad, E, Liu, W, Schultz, P.G. | | 登録日 | 2007-05-10 | | 公開日 | 2007-08-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Crystal structure of a biosynthetic sulfo-hirudin complexed to thrombin.
J.Am.Chem.Soc., 129, 2007
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1AJ7
 | | IMMUNOGLOBULIN 48G7 GERMLINE FAB ANTIBODY COMPLEXED WITH HAPTEN 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID. AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY | | 分子名称: | 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID, IMMUNOGLOBULIN 48G7 FAB (HEAVY CHAIN), IMMUNOGLOBULIN 48G7 FAB (LIGHT CHAIN) | | 著者 | Wedemayer, G.J, Wang, L.H, Patten, P.A, Schultz, P.G, Stevens, R.C. | | 登録日 | 1997-05-15 | | 公開日 | 1997-11-12 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural insights into the evolution of an antibody combining site.
Science, 276, 1997
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6X94
 | | An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical amino acid mutagenesis in Escherichia coli | | 分子名称: | 5'-O-(N-(L-SERYL)-SULFAMOYL)ADENOSINE, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Zambaldo, C, Koh, M, Nasertorabi, F, Han, G.W, Chatterjee, A, Stevens, R.C, Schultz, P.G. | | 登録日 | 2020-06-02 | | 公開日 | 2020-11-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical amino acid mutagenesis in Escherichia coli.
Bioorg.Med.Chem., 28, 2020
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1JES
 | | Crystal Structure of a Copper-Mediated Base Pair in DNA | | 分子名称: | 5'-D(*CP*GP*CP*GP*(DPY)P*AP*TP*(DRP)P*CP*GP*CP*G)-3', COPPER (II) ION | | 著者 | Atwell, S, Meggers, E, Spraggon, G, Schultz, P.G. | | 登録日 | 2001-06-18 | | 公開日 | 2001-11-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structure of a Copper-Mediated Base Pair in DNA
J.Am.Chem.Soc., 123, 2001
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6MTG
 | | A Single Reactive Noncanonical Amino Acid is Able to Dramatically Stabilize Protein Structure | | 分子名称: | DI(HYDROXYETHYL)ETHER, FORMIC ACID, GLYCEROL, ... | | 著者 | Li, J.C, Nasertorabi, F, Xuan, W, Han, G.W, Stevens, R.C, Schultz, P.G. | | 登録日 | 2018-10-19 | | 公開日 | 2019-06-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A Single Reactive Noncanonical Amino Acid Is Able to Dramatically Stabilize Protein Structure.
Acs Chem.Biol., 14, 2019
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1KEM
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1KEL
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1GAF
 | | 48G7 HYBRIDOMA LINE FAB COMPLEXED WITH HAPTEN 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID | | 分子名称: | 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID, CHIMERIC 48G7 FAB | | 著者 | Wedemayer, G.J, Patten, P.A, Stevens, R.C, Schultz, P.G. | | 登録日 | 1996-02-06 | | 公開日 | 1996-07-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | The immunological evolution of catalysis.
Science, 271, 1996
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3HWL
 | | Crystal Structure of T4 lysozyme with the unnatural amino acid p-Acetyl-L-Phenylalanine incorporated at position 131 | | 分子名称: | AZIDE ION, CHLORIDE ION, Lysozyme | | 著者 | Fleissner, M.R, Cascio, D, Schultz, P.G, Hubbell, W.L. | | 登録日 | 2009-06-17 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Site-directed spin labeling of a genetically encoded unnatural amino acid.
Proc.Natl.Acad.Sci.USA, 106, 2009
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1CKP
 | | HUMAN CYCLIN DEPENDENT KINASE 2 COMPLEXED WITH THE INHIBITOR PURVALANOL B | | 分子名称: | 1,2-ETHANEDIOL, PROTEIN (CYCLIN-DEPENDENT PROTEIN KINASE 2), PURVALANOL B | | 著者 | Gray, N.S, Thunnissen, A.M.W.H, Schultz, P.G, Kim, S.H. | | 登録日 | 1998-07-14 | | 公開日 | 1999-01-13 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.
Science, 281, 1998
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2HGZ
 | | Crystal structure of a p-benzoyl-L-phenylalanyl-tRNA synthetase | | 分子名称: | PARA-(BENZOYL)-PHENYLALANINE, Tyrosyl-tRNA synthetase | | 著者 | Liu, W, Alfonta, L, Mack, A.V, Schultz, P.G. | | 登録日 | 2006-06-27 | | 公開日 | 2007-06-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for the recognition of para-benzoyl-L-phenylalanine by evolved aminoacyl-tRNA synthetases.
Angew.Chem.Int.Ed.Engl., 46, 2007
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2PIS
 | | Efforts toward Expansion of the Genetic Alphabet: Structure and Replication of Unnatural Base Pairs | | 分子名称: | DNA (5'-D(*CP*GP*(CBR)P*GP*AP*AP*(FFD)P*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION | | 著者 | Matsuda, S, Fillo, J.D, Henry, A.A, Wilkins, S.J, Rai, P, Dwyer, T.J, Geierstanger, B.H, Wemmer, D.E, Schultz, P.G, Spraggon, G, Romesberg, F.E. | | 登録日 | 2007-04-13 | | 公開日 | 2007-10-30 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs.
J.Am.Chem.Soc., 129, 2007
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2PXH
 | | Crystal structure of a bipyridylalanyl-tRNA synthetase | | 分子名称: | 3-(2,2'-BIPYRIDIN-5-YL)-L-ALANINE, Tyrosyl-tRNA synthetase | | 著者 | Liu, W, Xie, J, Schultz, P.G. | | 登録日 | 2007-05-14 | | 公開日 | 2008-02-05 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | A genetically encoded bidentate, metal-binding amino acid.
Angew.Chem.Int.Ed.Engl., 46, 2007
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1FL6
 | | THE HAPTEN COMPLEXED GERMLINE PRECURSOR TO SULFIDE OXIDASE CATALYTIC ANTIBODY 28B4 | | 分子名称: | 1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO]METHYLPHOSPHONIC ACID, ANTIBODY GERMLINE PRECURSOR TO 28B4 | | 著者 | Yin, J, Mundorff, E.C, Yang, P.L, Wendt, K.U, Hanway, D, Stevens, R.C, Schultz, P.G. | | 登録日 | 2000-08-11 | | 公開日 | 2001-11-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A comparative analysis of the immunological evolution of antibody 28B4.
Biochemistry, 40, 2001
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1FL5
 | | THE UNLIGANDED GERMLINE PRECURSOR TO THE SULFIDE OXIDASE CATALYTIC ANTIBODY 28B4. | | 分子名称: | ANTIBODY GERMLINE PRECURSOR TO ANTIBODY 28B4, SULFATE ION | | 著者 | Yin, J, Mundorff, E.C, Yang, P.L, Wendt, K.U, Hanway, D, Stevens, R.C, Schultz, P.G. | | 登録日 | 2000-08-11 | | 公開日 | 2001-11-14 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A comparative analysis of the immunological evolution of antibody 28B4.
Biochemistry, 40, 2001
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3D6V
 | | Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase | | 分子名称: | 4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE, BETA-MERCAPTOETHANOL, Tyrosyl-tRNA synthetase | | 著者 | Liu, W, Tippmann, E, Mack, A.V, Schultz, P.G. | | 登録日 | 2008-05-20 | | 公開日 | 2008-05-27 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A genetically encoded diazirine photocrosslinker in Escherichia coli
ChemBioChem, 8, 2007
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3FCT
 | | MATURE METAL CHELATASE CATALYTIC ANTIBODY WITH HAPTEN | | 分子名称: | CADMIUM ION, CALCIUM ION, MAGNESIUM ION, ... | | 著者 | Romesberg, F.E, Santarsiero, B.D, Barnes, D, Yin, J, Spiller, B, Schultz, P.G, Stevens, R.C. | | 登録日 | 1999-06-13 | | 公開日 | 1999-06-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and kinetic evidence for strain in biological catalysis.
Biochemistry, 37, 1998
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3D6U
 | | Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase | | 分子名称: | 4-[3-(TRIFLUOROMETHYL)DIAZIRIDIN-3-YL]-L-PHENYLALANINE, BETA-MERCAPTOETHANOL, Tyrosyl-tRNA synthetase | | 著者 | Liu, W, Tippmann, E, Mack, A.V, Schultz, P.G. | | 登録日 | 2008-05-20 | | 公開日 | 2008-05-27 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A genetically encoded diazirine photocrosslinker in Escherichia coli
ChemBioChem, 8, 2007
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1PVP
 | | BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, ALSHG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7 | | 分子名称: | 34-MER, Recombinase cre | | 著者 | Baldwin, E.P, Martin, S.S, Abel, J, Gelato, K.A, Kim, H, Schultz, P.G, Santoro, S.W. | | 登録日 | 2003-06-28 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Chem.Biol., 10, 2003
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3FCA
 | | Genetic Incorporation of a Metal-ion Chelating Amino Acid into proteins as biophysical probe | | 分子名称: | Cysteine synthase, ZINC ION | | 著者 | Wang, F, Lee, H, Spraggon, G, Schultz, P.G. | | 登録日 | 2008-11-21 | | 公開日 | 2009-02-17 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.149 Å) | | 主引用文献 | Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe.
J.Am.Chem.Soc., 131, 2009
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1PVQ
 | | BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE ENGINEERED RECOGNITION SITE LOXM7 | | 分子名称: | DNA 34-MER, Recombinase cre | | 著者 | Baldwin, E.P, Martin, S.S, Abel, J, Gelato, K.A, Kim, H, Schultz, P.G, Santoro, S.W. | | 登録日 | 2003-06-28 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Chem.Biol., 10, 2003
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1PVR
 | | BASIS FOR A SWITCH IN SUBSTRATE SPECIFICITY: CRYSTAL STRUCTURE OF SELECTED VARIANT OF CRE SITE-SPECIFIC RECOMBINASE, LNSGG BOUND TO THE LOXP (WILDTYPE) RECOGNITION SITE | | 分子名称: | 34-MER, Recombinase CRE | | 著者 | Baldwin, E.P, Martin, S.S, Abel, J, Gelato, K.A, Kim, H, Schultz, P.G, Santoro, S.W. | | 登録日 | 2003-06-28 | | 公開日 | 2004-02-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | A specificity switch in selected cre recombinase variants is mediated by macromolecular plasticity and water.
Chem.Biol., 10, 2003
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